2012 Scientific Report - Queensland Children's Medical Research ...
2012 Scientific Report - Queensland Children's Medical Research ...
2012 Scientific Report - Queensland Children's Medical Research ...
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Eat Smart for Success: Investigating the use of pharmacotherapy in adolescents<br />
for weight loss maintenance: The role of appetite (Jennifer Batch)<br />
Eat Smart for Success aims to assist obese adolescents maintain weight loss after a dietary<br />
intervention. One of the major issues in obesity management is that patients who lose weight<br />
often regain all the weight in the following 1-2 years. This study is specifically designed to try to<br />
find a solution to this problem by adding metformin. We will study metformin’s effect on<br />
fullness (satiety) such that the drive to eat and the amount of food eaten are reduced. We will<br />
also study the effect of metformin on gut hormones produced in response to food in obese and<br />
healthy weight adolescents. We know that obese adolescents have a high risk of becoming<br />
obese adults with early cardiovascular disease. Assisting adolescents to maintain weight loss will<br />
help prevent cardiovascular disease in adult life.<br />
Awards<br />
‣ Karen Shann, Best New Poster Presenter, Australian Diabetes Educator Association<br />
<strong>2012</strong><br />
<strong>Research</strong> Grants and Contracts<br />
Years Grant Agency Chief<br />
Investigators<br />
2011-<br />
2013<br />
Children’s Health<br />
Foundation,<br />
Brisbane<br />
A/Prof L<br />
Conwell, Dr R<br />
Greer<br />
Title<br />
A clinical national framework for<br />
care of infants and children with<br />
hyperinsulinism of infancy (HI)<br />
Amount<br />
$77,000<br />
2009-<br />
2013<br />
Australian<br />
Paediatric<br />
Endocrine Group<br />
(APEG) / Merck<br />
Serono<br />
A/Prof L Conwell<br />
Characterisation of the<br />
metabonomic profile of<br />
adolescents with type 1 diabetes<br />
and assessment of association<br />
with cardiovascular risk factors.<br />
$15,000<br />
2009-<br />
2013<br />
Children’s Health<br />
Foundation,<br />
Brisbane / QCMRI<br />
A/Prof L Conwell<br />
Metabonomics, heart and blood<br />
vessel risk in teenagers with type 1<br />
diabetes.<br />
$64,280<br />
2009-<br />
2013<br />
Children’s Health<br />
Foundation,<br />
Brisbane / QCMRI<br />
A/Prof L Conwell<br />
Metabonomics, heart and blood<br />
vessel risk in teenagers with type 1<br />
diabetes.<br />
$21,000<br />
2011-<br />
ongoing<br />
Juvenile Diabetes<br />
<strong>Research</strong><br />
Foundation<br />
A/Prof L Conwell,<br />
Prof J Batch<br />
(Associate<br />
Investigators)<br />
Australasian Paediatric Endocrine<br />
Group Clinical Trials Network<br />
$910,463<br />
QCMRI <strong>Scientific</strong> <strong>Report</strong> <strong>2012</strong> 12
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