2012 Scientific Report - Queensland Children's Medical Research ...

More documents

Recommendations

Info

Collaborating with oncology This study involves a collaboration that began in 2012 between the CLEAR group and the Oncology Department at Royal Children’s Hospital. Children with blood cancers or other conditions who are treated with high dose chemotherapy, radiation and stem cell transplantation may develop significant and life-threatening chronic lung diseases even after their cancer has been cured. The aim of this project is to identify a better test of breathing function to identify the children likely to develop problems earlier to enable earlier treatment and better monitoring of response to treatment. This study began in 2012 and will continue into 2013. Lung function in children from Mexico Collaboration between the CLEAR group and the National Institute of Public Health, Department of Environmental Health, Mexico aimed to develop reference values for the Forced Oscillation Technique (FOT) suitable for use in Mexican preschool aged children. Current FOT reference ranges are based on a Caucasian population, limiting the clinical utility of the FOT in other ethnic populations. This collaboration developed ethnic appropriate FOT reference ranges for Mexican children and allows for the appropriate interpretation of lung function measurements for Mexican children. These data have been published in Spanish for use in Latin American countries. Environmental health How the environment affects health Through a retrospective analysis of data from the RAINE group in Perth, in 2012 we were able to identify associations with environmental toxins and worse health outcomes in children. These health outcomes were related to mental health, like ADHD, and physical health, like growth and asthma. While these results have been presented at conferences in 2012, the data will be available in 2013. Summary of Research Activities and Achievements The Children’s Health and Environment Program (CHEP) In line with the (World Health Organisation) WHO Global Plan for Action for Children’s Health CHEP aims to promote and improve children’s environmental health through multidisciplinary research. Its terms of reference (TOR) specifically address strategies 1, 2 & 5 of the World Health Organisation (WHO) Global Plan: CHEP TOR1: To conduct research aimed at understanding the mechanisms underlying the development of childhood diseases of environmental origin; CHEP TOR2: To strengthen international and intersectoral collaborative research on children’s environmental health. QCMRI Scientific Report 2012 40
CHEP TOR3: To Educate and raise awareness about prevention of environmental exposures and environmentally-related diseases in children. CHEP is administratively located within the QCMRI. The Program consists of: ‣ A Director ‣ An external Scientific Advisory Board, with representation from QCMRI, UQ Faculty of Health Sciences and from key stakeholders ‣ Senior Centre Staff ‣ Project leaders and staff Environmental Contributions to Burden of Disease: Rosana Norman, James Scott, Peter Sly An important aim of the Children's Health and Environment Program is to establish a framework for understanding the environmental contribution to burden of disease among children in Australia. The focus is on non-communicable disease outcomes including asthma/respiratory disease, neurodevelopmental, mental and behavioural disorders, obesity and diabetes and childhood cancers. The research is part of a collaborative effort with researchers at the UQ School of Population Health (Lennert Veerman) and School of Medicine (Geoffrey Cleghorn) as well as QUT (Fiona Harden and Leisa-Maree Toms), Menzies School of Health Research (Ross Bailie), NSW Cancer Council (Freddy Sitas) and ENTOX (Jochen Mueller) and has included reviews on the consequences of exposure to brominated flame retardants and on the environmental contribution to autism, childhood cancers and obesity and diabetes. This work has already resulted in a series of publications including an invited commentary. Other related research activities are described in more detail below. The long-term consequences of child maltreatment: Rosana Norman, James Scott The project team is led by Dr Rosana Norman and also includes Dr James Scott from the University of Queensland Centre for Clinical Research and Alexander Butchart from the World Health Organization. The researchers reviewed all published studies that included health outcomes for individuals who had been physically or emotionally abused or neglected in childhood. The researchers found that individuals who had been emotionally abused as children were about three times more likely to develop depression, while individuals who had been physically abused or neglected were one-and-a-half to two times more likely to develop depression than people who had not been abused or neglected. They also established a link between anxiety disorders, drug abuse, and suicidal behaviour and childhood abuse and found that children who had been maltreated had a higher risk of sexually transmitted infections and risky sexual behaviour as adults than people who had not experienced abuse. The study confirms that all forms of child maltreatment should be considered important risks to health with a sizeable impact on major contributors to the burden of disease in all parts of the world. This work was recently published in PLoS Medicine. The next phase of the research aims to quantify the cost of child maltreatment and to identify cost-effective interventions. QCMRI Scientific Report 2012 41
Page 2 and 3: QCMRI Director’s Report .........
Page 4 and 5: QCMRI Scientific Report 2011 4
Page 6 and 7: disease lead by Dr. Andrew Moore. O
Page 8 and 9: 2. Keating J, Tsoli M., Hallahan A.
Page 12 and 13: Eat Smart for Success: Investigatin
Page 14 and 15: Staff Profile Name Prof Jennifer Ba
Page 16 and 17: Research Group Contact Details Depa
Page 18 and 19: Publications Peer Reviewed Manuscri
Page 22 and 23: Awards & Achievements ‣ Helen Pet
Page 24 and 25: onchiectasis: study protocol for a
Page 26 and 27: Staff Profile Name Prof Anne Chang
Page 28 and 29: Research Group Contact Details Quee
Page 30 and 31: Research Activities and Achievement
Page 32 and 33: Figure 4: AKAPRI Artwork. Artist: I
Page 34 and 35: Research Publications Full Peer Rev
Page 36 and 37: Major Partners ‣ The National Cen
Page 38 and 39: Children’s Lung, Environment and
Page 42 and 43: Bullying in Childhood and Adolescen
Page 44 and 45: 2012- 2014 National Health and Rese
Page 46 and 47: 17. Robinson P, Schechter M, Winfie
Page 48 and 49: Research Degrees Ongoing Name Super
Page 50 and 51: Airways Infections, Inflammation &
Page 54 and 55: Queensland Paediatric Infectious Di
Page 56 and 57: 2011- 2015 Hospital Foundation NHMR
Page 60 and 61: 22. Lambert SB, Ware RS, Cook AL, M
Page 62 and 63: 44. Whiley DM, Jacob K, Nakos J, Bl
Page 64 and 65: National and International Collabor
Page 66 and 67: Centre for Children’s Burns and T
Page 68 and 69: Years Grant Agency 2012 RCH Foundat
Page 70 and 71: Staff Profile Name Prof Roy Kimble
Page 72 and 73: ‣ 2009-present: Professor Zee Upt
Page 74 and 75: QCMRI Scientific Report 2011 88 QCM
Page 76 and 77: Professor Jeanine Young, appointed
Page 78 and 79: 6. Watson K, Young J, Barnes M. (20
Page 80 and 81: Centre for Online Health Message fr
Page 82 and 83: Summary of Research Activities and
Page 84 and 85: This project represents a significa
Page 86 and 87: 13. Fatehi, F. and R. Wootton (2012
Page 88 and 89: Ms Joanne Grey Senior Research Comm
Page 90 and 91:
‣ Queensland Cerebral Palsy and R
Page 92 and 93:
Children’s Allied Health Research
Page 94 and 95:
2011- 2013 Foundation for Children
Page 96 and 97:
18. Wallen, M. A., & Ziviani, J. M.
Page 98 and 99:
Research Degrees Ongoing Name Super
Page 100 and 101:
Biostatistics and Epidemiology Unit
Page 102 and 103:
6. Benfer, KA; Weir, KA; Bell, KL;
Page 104 and 105:
Infectious Diseases (ORChID): a dyn
Page 107:
QCMRI Scientific Report 2011 114
show all

2012 Scientific Report - Queensland Children's Medical Research ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?