BioMedical Engineering OnLine 2006, 5:42http://www.biomedical-engineering-online.com/content/5/1/42A δ ∗A δ ∗∗A θwhereas <strong>the</strong> friction coefficient for a parabolic profile is K ν= -8 π ν. The corresponding momentum correction coefficientis given byγ + 2χ( xt , ) = ,γ + 1which is 4/3 in <strong>the</strong> parabolic case. Such fac<strong>to</strong>rs can beused for <strong>the</strong> purpose of correlating o<strong>the</strong>r variables as wellas for direct calculation of pressure drop. We note that in<strong>the</strong> presence of a stenosis <strong>the</strong> <strong>to</strong>tal losses under <strong>the</strong>assumption of Hagen-Poiseuille flow are underestimated[55]. This comes mainly from underestimating <strong>the</strong> viscousforces and disregarding <strong>the</strong> losses caused by flow separationat <strong>the</strong> diverging end of <strong>the</strong> stenosis [64,65].Boundary <strong>layer</strong> derived viscous friction and momentum correctionDeveloping flow conditions in ducts of multiply connectedcross-sections generally make it difficult <strong>to</strong> use <strong>the</strong>right friction fac<strong>to</strong>r. A variety of cross-sections are discussedin [45]. In those situations <strong>the</strong> similarity parametersare preferably based on <strong>the</strong> free stream velocity and<strong>the</strong> square root of <strong>the</strong> cross-sectional flow area as characteristiclength scale i.e. = A . Consequently we define<strong>the</strong> Reynolds number Re A=V / V , <strong>the</strong> Womersleyhave multiplied Re and Sr by a fac<strong>to</strong>r ofis multiplied byδ ∗θDisplacement tube Figure 6 thickness and displacement area in a deformedDisplacement thickness and displacement area in adeformed tube. Illustration of <strong>the</strong> displacement thicknessδ*, <strong>the</strong> momentum thickness θ and <strong>the</strong> <strong>to</strong>tal displacementthickness δ** in a deformed cross-section. The related areasare <strong>the</strong> displacement area A δ* (dark grey), <strong>the</strong> momentumarea A θ (light grey) and <strong>the</strong> <strong>to</strong>tal displacement area A δ** = A δ*+ A θ (light + dark grey) respectively.( 43)number or frequency parameter WoA = W / V2Woand <strong>the</strong> Strouhal number SrA = = ω. Here ωRe Vis <strong>the</strong> angular frequency defined as ω = 2πf, with f <strong>the</strong> basefrequency of pulse wave oscillation. In o<strong>the</strong>r words weδ ∗∗1 2π , while Woπ . In <strong>the</strong> calculations we have given<strong>the</strong> Reynolds number inside <strong>the</strong> stenosis, Re st , based on .As previously mentioned <strong>the</strong> surface line of <strong>the</strong> flat portionof <strong>the</strong> non-circular duct dominates <strong>the</strong> circular portionat severe deformations, so that <strong>the</strong> computation ofviscous forces is based on plane wedge flow. Consequently<strong>the</strong> thickness of <strong>the</strong> <strong>boundary</strong> <strong>layer</strong> is estimated in<strong>the</strong> xz-plane. Fur<strong>the</strong>r we assume that <strong>the</strong> <strong>boundary</strong> <strong>layer</strong>has constant thickness along <strong>the</strong> circumference as illustratedin Figure 6. The latter assumption allows a simplederivation of <strong>the</strong> momentum correction coefficient and<strong>the</strong> viscous friction term. Integration over <strong>the</strong> cross-sectionleads <strong>to</strong> geometric relations for <strong>the</strong> areas occupied by<strong>the</strong> displacement thickness δ* and <strong>the</strong> <strong>to</strong>tal displacementthickness δ** in that cross-section. They are expressed asA δ* = 2B δ* + π [R 2 d - (R d - δ*) 2 ], (44)A δ** = 2B δ** + π [R 2 d - (R d - δ**)2 ], (45)It is obvious that A d > A δ** and A d > A δ* have <strong>to</strong> be satisfied<strong>to</strong> make sure that <strong>the</strong> flow is not fully developed. Themomentum correction coefficient can be found by satisfyingmass conservation for <strong>the</strong> mean flow and <strong>the</strong> core flowbyV (A - A δ* ) = A u, (46)which can be used <strong>to</strong>ge<strong>the</strong>r with equation (22) and (45)in <strong>the</strong> definition for <strong>the</strong> momentum correction (43), sothat( ) =χ xt ,A ∗∗A νA A V da A A − A − δ21∗∗xδ=A∫=.2 A 2 22−( A − A ) ⎛ A∗∗∗δδ1 − δ ⎞⎜⎝ A ⎟⎠( )( 47 )The uniform inflow profile is identical <strong>to</strong> χ = 1, while <strong>the</strong>developing profile reaches its far downstream value of1.39 after <strong>the</strong> entrance length within less than 4.5% from<strong>the</strong> analytical solution for <strong>the</strong> parabolic flow profile givenin equation (43). We note that in <strong>the</strong> linearised system <strong>the</strong><strong>to</strong>tal cross-section A in equation (47) is replaced by A d .According <strong>to</strong> equation (34) <strong>the</strong> friction fac<strong>to</strong>r built with<strong>the</strong> pressure dependent surface line, U p (x, t) isFvUpv B+Rdx, twf .ρ τ 2 π20θ( ) =− =−( )( 48 )Computations in a uniform tube show good agreement <strong>to</strong><strong>the</strong> friction fac<strong>to</strong>r of <strong>the</strong> parabolic profile given in equation(42). After <strong>the</strong> entrance length <strong>the</strong> friction fac<strong>to</strong>rcomputed via <strong>the</strong> <strong>boundary</strong> <strong>layer</strong> <strong>the</strong>ory reached its fardownstream value <strong>to</strong> within 7%. Additionally <strong>the</strong> Fanningfriction fac<strong>to</strong>r Reynolds number product in aPage 10 of 25(page number not for citation purposes)
BioMedical Engineering OnLine 2006, 5:42http://www.biomedical-engineering-online.com/content/5/1/42through <strong>the</strong> <strong>boundary</strong> <strong>layer</strong>: t d = δ 2 /V
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