OPERATOR'S MANUAL BIOPROtect II Vent to ... - Baker Company

OPERATOR’S MANUALBIOPROtect IIVent to Room / Vent to C.E.C /Vent to H.E.CBio-Containment EnclosureThis manual includes information for installation, operation, maintenance and spare parts.We recommend that it be kept near the cabinet for ready reference.June, 2007Rev CTHE BAKER COMPANY161 Gatehouse Rd., Sanford, Maine 04073 USA ⋅ (207) 324-8773 ⋅ 1-800-992-2537 ⋅ FAX (207) 324-2632Internet address: http// www.bakerco.com “Creating Immaculate Atmospheres”

The Baker CompanyINTRODUCTION AND WELCOMEIt is a pleasure to welcome you to the growing number of customers who own and operate Bakerbiological safety cabinets. As the inventors of the laminar flow biological safety cabinet and the leaders inthe field, Baker people take special pride in providing a cabinet that is designed for maximum performance.Your new BIOPROtect II cabinet includes many unique features which are included to give you superiorperformance, simpler maintenance and lower life cycle cost. Your BIOPROtect II cabinet is designed forboth safety and value.In addition to the high quality you expect from all Baker equipment, this model has been ergonomicallydesigned to provide the lab user with many exciting design features. The revolutionary ergonomic designwill help prevent repetitive motion injury, reduce fatigue and lab accidents and enhance productivity.You will find your BIOPROtect II cabinet suitable for use not only for research and clinical diagnostic workinvolving tissue culturing of possibly infectious samples, but also for I.V. drug preparations and otherpharmaceuticals that could have adverse health effects on operators and other techniques requiring acontamination-free atmosphere.Please note that all open-front containment cabinets, including this one, are for use with low to moderaterisk agents only. Open-front cabinets do not provide absolute protection for the user. The adequacy of acabinet for user safety should be determined on-site by an industrial hygienist, safety officer or otherqualified person. Remember that you, the owner and user, are ultimately responsible and that you use yourcabinet at your own risk.We recommend that this manual, along with factory test report, be kept near the cabinet for convenientreference by operators and qualified maintenance personnel. If you have any questions about the use orcare of your new BIOPROtect II cabinet, please do not hesitate to contact our Customer ServiceDepartment at 800-992-2537 for assistance or e-mail us at bakerco@bakerco.com.Sincerely,Dennis EaglesonPresident, CEOThe Baker Company, Inc.P.O. Drawer E, Sanford, Maine 04073 (207) 324-8773 1-800-992-2537 FAX (207) 324-3869Visit our website at www.bakerco.com

Table of ContentsINTRODUCTION AND WELCOME ................................................................................................ iTable of Contents ............................................................................................................................... iiI - FUNCTION AND DESCRIPTION OF THE BIOPROtect II CABINET .................................... 1Airflow Inside the BIOPROtect II Cabinet .................................................................................... 1Access to the Work Area................................................................................................................ 2Design Details ................................................................................................................................ 3Performance assurance.............................................................................................................. 3All-metal plenums..................................................................................................................... 3Tested HEPA filters .................................................................................................................. 3Work area lighting .................................................................................................................... 3Cable Port.................................................................................................................................. 3Optional Height Adjustable Cart.................................................................................................... 3Specifications ................................................................................................................................. 4Dimensions: .............................................................................................................................. 4Weights ..................................................................................................................................... 4Utilities:.......................................................................................................................................... 4Mechanical................................................................................................................................ 4Electrical ................................................................................................................................... 4Environmental Conditions.............................................................................................................. 5Symbols and Terminology ............................................................................................................. 5II - PREPARING THE BIOPROtect II CABINET FOR USE .......................................................... 6The Uses of the BIOPROtect II...................................................................................................... 6Location Within the Laboratory..................................................................................................... 6Operator Controls:.......................................................................................................................... 7Blower On / Off Switch – ......................................................................................................... 7Light On / Off Switch – ............................................................................................................ 7Mute switch - ............................................................................................................................ 7Left Side & Right Side Outlet On / Off – ................................................................................. 8Ground Fault Circuit Interrupter .................................................................................................... 8Air Pressure Alarm......................................................................................................................... 8Door Operations ............................................................................................................................. 9To open the viewscreen: ........................................................................................................... 9To open the door:...................................................................................................................... 9

Removing the cart .......................................................................................................................... 9Start-up procedure ........................................................................................................................ 11Reacting to Spills.......................................................................................................................... 12Decontamination .......................................................................................................................... 13About the HEPA Filters ............................................................................................................... 15IV - ON-SITE CHECKS AND MAINTENANCE PROCEDURES ............................................... 16Filter Media and Seal Leak Tests ................................................................................................. 16Procedure for filter leak tests........................................................................................................ 17The Airflow Balance .................................................................................................................... 18Airflow Smoke Pattern Test ......................................................................................................... 19Grounding Continuity Test........................................................................................................... 19Calibration procedure for Modus Airflow alarm(Digital Differential Pressure Monitor). .......... 20Initial Set Point Settings.......................................................................................................... 20Low Flow Alarm Setting ........................................................................................................ 20Check the Calibration ............................................................................................................. 20Modus Programming Instructions ................................................................................................ 211.) Programming the Alarm Set points ................................................................................... 212.) Programming the Relay Dead band................................................................................... 213.) Returning to Normal Operation......................................................................................... 21Maintenance Notes ....................................................................................................................... 22Replacing the HEPA Filter........................................................................................................... 22Changing the Exhaust Filter.................................................................................................... 22Changing the Supply Filter ..................................................................................................... 23V. - TROUBLE SHOOTING .......................................................................................................... 24REPLACEMENT PARTS LIST .................................................................................................. 26VI. APPENDIX ................................................................................................................................ 27Modus Installation and Operation Handbook............................................................................... 28BGA-BIOPROtect II Vent to Room Page 1................................................................................. 42BGA-BIOPROtect II Vent to Room Page 2................................................................................. 43BGA-BIOPROtect II Vent to Room Page 3................................................................................ 44BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 1 .............................................. 45BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 2 .............................................. 46BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 3 .............................................. 47

BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 1......................................... 48BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 2......................................... 49BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 3......................................... 50BGA-BIOPROtect II Optional Cart ............................................................................................. 51Wiring Diagram-Standard BIOPROtect II ................................................................................... 52Wiring Diagram – Master BIOPROtect II ................................................................................... 53WARRANTY................................................................................................................................... 54Test Report…………………………………………………………………………….Attached

I - FUNCTION AND DESCRIPTION OF THE BIOPROtect II CABINETThe BIOPROtect II is a Class II Bio-Containment Enclosure designed to house laboratory robotics orlarge apparatus that would not ordinarily fit in a standard Class II Biological Safety Cabinet (BSC). Someimportant features of the BIOPROtect II include, vertical laminar airflow, a front access opening, as well assupply & exhaust HEPA filters. The unit is designed to protect not only the environment and the peopleusing the cabinet, but also the product within from airborne contaminants. The BIOPROtect II can beconfigured to vent three different ways. Vent to the room, Vent to a Canopy Exhaust Connection (C.E.C.)via a house exhaust system or, Vent to a Hard Exhaust Connection (H.E.C.) via a house exhaust system.Although your unit has passed a microbiological test, a modification of NSF/ANSI standard-49-2002e, theBIOPROtect II is not currently listed with the NSF.Airflow Inside the BIOPROtect II CabinetFigure 1 shows the name and location of component parts and the typical airflow pattern of theBIOPROtect II.The stainless steel metal diffuser (1) just below the supply HEPA (High Efficiency Particulate Air) filterassures that the work area is bathed in HEPA filtered air. The supply air stream splits so that some isdirected into the front grille (2) and the balance is pulled into the perforated grilles on the rear wall (3). On aflat table top, in the absence of any obstacles, the air should split roughly in the center of the table.Because the cabinet must take in air to replace the air which is expelled through the exhaust filter, thesame quantity of room air enters the cabinet through the eight inch front access opening. The flow of theintake air provides the personnel protection (containment) aspect of the cabinet.The front grille of the cabinet is integral to the large hinged doors. These doors, as well as the side andrear walls, are maintained under a negative pressure. Air is drawn from the front intake grilles, into thehollow doors, and into the side walls. In this manner the outside air that is drawn into the cabinet as intake isnot allowed to penetrate the table top area of the cabinet.Any and all contaminated air that is captured in the cabinet’s negative pressure plenums (front doors,sidewalls, rear walls or upper plenum) is pulled into the cabinet’s blower (4). The blower discharges into a steelbox that is a common plenum for the supply and exhaust HEPA filters (5). In this manner, all the air that ishandled by the cabinet is HEPA filtered. The BIOPROtect II will exhaust a quantity of air (6) equal to thatreceived at the front intake grilles. If a leak should occur in a contaminated pressure plenum the negativepressure will create suction and pull air in, not allowing it to escape into the laboratory. If there is a leakfrom the positive pressure plenum, the surrounding negative pressure area will recapture the contaminated airand recirculate it through a HEPA filter.Page 1 of 54

Figure 1 Typical section with airflow visualization arrowsAccess to the Work AreaThe BIOPROtect II is provided with three modes of access to the work area; via the large hinged doorsthat can be opened to access the entire work area, the hinged viewscreens (providing access to the worksurface) or from the 8” x 42” access (sash) openings between the bottom of the closed viewscreens and theair intake grates. The primary means of access must be through the 8” sash openings. This is the only meansof access that will ensure the user protection from contaminants within the enclosure.The operator is only protected from airborne particulate when the large front doors and the hinged viewscreensare closed and secured to provide the 8”x 42” access (sash) openingsFor easy set-up of equipment in the work area, the BIOPROtect II has two large doors that exposes theentire work area from floor to ceiling to an area of 102” wide x 68” tall.Page 2 of 54

Design DetailsPerformance assuranceMeticulous care in manufacturing is followed by more than 14 separate performance tests prior toshipment of your cabinet. In addition, a complete factory test report on the operation of your unit isincluded at the rear of this manual.All-metal plenumsThe work area surfaces and plenums of your BIOPROtect II have been constructed entirely of metalin order to provide strength, durability, air-tightness and resistance to deterioration. Externalconstruction is of 16-gauge cold-rolled steel, protected by a smooth white baked enamel finish.Tested HEPA filtersSupply and exhaust HEPA filters in the BIOPROtect II unit have been found to be 99.99 percenteffective on particles of 0.3 micron size. Each filter is scan-tested to assure leak-free installation.Work area lightingThe fluorescent lights are externally mounted within the light canopy to minimize heat buildup in thework area. The unit uses four common F32T8 fluorescent bulbs powered by an efficient and reliableelectronic ballast.Cable PortA 2.75” I.D. cable port is provided in each side wall to accommodate communications ports fromprocess equipment without compromising performance.Optional Height Adjustable CartThe all stainless steel cart, which is optional on the BIOPROtect II was designed to accommodateprocess equipment weighing no more than 500 Lbs. It’s work surface dimensions are 90” Wide x 34” Deep.The height of the worksurface can be adjusted by the operator from 27” to 39” by using the manual crankprovided at the front of the cart. For ideal ergonomic performance the cart should be adjusted so that thework table of the equipment is at the same level as the front intake grille of door on the front of the cabinet.The cart is provided with swivel casters, all of which are locking. To retract the cart from the work area,tip the foot operated locking devices at each front caster to a horizontal position then pull the cart out of thework area. To return the cart to the cabinet push the cart back into the work area and lock the front castersby pushing down on the foot operated locking devices. Make certain that the crank handle for the lift systemis facing the front of the cabinet and is retracted under the work table before closing the door.Page 3 of 54

SpecificationsDimensions:Outside: 116.88”W x 50.00”D x 107”H (over junction boxes)Usable work area: 102”W x 36.5”D x 75”H (under diffuser)Cart worksurface: 90”W x 34” D x (27”- 39”) H (height adjusted by operator).WeightsUnit weight: The weight of the BIOPROtect II cabinet is approximately 2315 lbs.Cart weight: The weight of the BIOPROtect II cart is approximately 500 lbs.Maximum worksurface capacity: 500 Lbs. uniform load.Point loads not to exceed 125 Lbs. eachUtilities:MechanicalFour (4) 3/8” NPT female connections provided for plumbing; all are pre-plumbed to the top of theunit using 3/8” copper tubing. No service fixtures or valves are provided. User must supply fixtures tomate with 3/8” NPT female connection on side walls (see general arrangement drawing for details).ElectricalCaution: This cabinet is powered from more that one power source. The cabinet is not electrically safe unlessall power sources are disconnected. Use proper Lock Out / Tag Out procedures.All electrical wiring should comply with the National Electrical Code and any applicable Local Electrical Codesat the site of installation.The standard BIOPROtect II has three junction boxes located on the front of the top deck. Thefollowing services need to be connected to the junction boxes.One 220Volt, 20Amp, 60 Hz, Single phase connection to power the two blowers. This circuit should bewired using 12 AWG wire and provided with a 20 Amp circuit breaker that will serve as a disconnectfor this power supply.One 120 V, 15Amp, 60 Hz, Single phase connection for control power and power to the left side wallduplex outlet. This circuit should be wired using 14 AWG wire and provided with a 15 Amp circuitbreaker that will serve as a disconnect for this power supply.One 120 V, 15Amp, 60 Hz, Single phase connection for power to the right side wall duplex outlet. Thiscircuit should be wired using 14 AWG wire and provided with a 15 Amp circuit breaker that willserve as a disconnect for this power supply.The circuit breakers for these services are to be located in close proximity to the cabinet.Otherconnections may be required for optional equipment.The BIOPROtect II incorporates solid-state ‘Stedivolt’ controllers to adjust the blower motor speed. Thisunit compensates for some variation in incoming line voltage. The usable voltage range is 105 to 240VPage 4 of 54

AC. You will need to consult the most recent certification test report on the unit to determine what thevoltage setting should be for your unit.Environmental ConditionsThe BIOPROtect II is designed to be used under the following conditions:Indoor useAltitudes up to 2000 metersTemperature range from 5° C to 40° CRelative humidity up to 80%Main supply voltage105 to 130 V AC for 120V circuits200 to 240V AC for 220V circuitsMaximum relative humidity 80 percent for temperatures up to 31°C decreasing linearly to 50 percentrelative humidity at 40°C.Transient over voltages according to Installation Category (OVERVOLTAGE CATEGORIES) II per UL61010-1, Annex J.Pollution Degree 2Symbols and TerminologyProtective Earth: Any terminal which is intended for connection to an external protectiveconductor for protection against electric shock in case of a fault.!General Caution: Refer to the instruction manual for information regarding personnel andenvironment protection.Page 5 of 54

The Uses of the BIOPROtect II.II - PREPARING THE BIOPROtect II CABINET FOR USEThe BIOPROtect II cabinet has been designed to provide a work area that protects the experiment fromthe environment (Product protection), and protects the users from the experiment (personnel protection or‘containment’). The laminar flow biological safety cabinet is designed for work with Biosafety Levels 1, 2and 3 (low to moderate risk) agents as listed in The Center for Disease Control’s “Biosafety inMicrobiological and Biomedical Laboratories”, U.S. Department of Health and Human Services, PublicHealth Service, Centers for Disease Control and National Institutes of Health, U.S. Government PrintingOffice, Washington, D.C. 20402. HHS publication number (CDC) 84-8395.Extremely high risk agents assigned to Biosafety level 4 should never be used in this cabinet except in acertified BSL4 suit room. Please consult your safety professional for a proper risk assessment.Cautions* The use of any hazardous material in the cabinet requires that it be monitored by an industrial hygienist, safetyofficer or other qualified individual.* Explosive or flammable substances should never be used in the cabinet unless a qualified safety professionalhas evaluated the risk.* If hazardous biological work is to be performed, apply the appropriate biohazard decal which is enclosed. Thisis in accord with OSHA regulations, volume 39, number 125, Part II.* If chemical, radiological or other non-microbiological hazards are present, be sure to employ appropriateprotective measures in addition to formaldehyde decontamination. Call upon a suitably trained individual tomonitor the operation.Also refer to section 2 of this manual the section entitled “Decontamination”Location Within the LaboratoryPROPER PLACEMENT WITHIN THE LABORATORY IS ESSENTIAL.The ideal location for any laminar flow biological safety cabinet is in a dead-end corner of the laboratoryaway from personnel traffic, vents, doors, windows or any other sources of disruptive air currents. Publishedresearch from The Baker Company (see Rake ASM paper, reference #34 in Appendix) and unpublished testsperformed at the National Cancer Institute show that if a draft or other disruptive air current were to exceedthe intake velocity of the cabinet, then contamination can enter the work area or escape from it.Page 6 of 54

III - PROPER CABINET USECaution:If the proper use of the cabinet is not understood or the cabinet is not operated correctly itwill not provide an adequate personnel or product protection.The BIOPROtect II is designed for continuous operation. The Baker Company recommends continuousoperation to keep the interior work space clean and free of unwanted particles. If the blower is not running,the workspace of the cabinet will become contaminated with room air. It would be helpful for operators tolearn about the capabilities and limitations of the cabinet by reading some of the available literature. TheEagleson Institute offers several videotapes and an interactive CD which illustrate proper operationtechniques for biological safety cabinets.A biological safety cabinet is a valuable supplement to good sterile technique, but is not a replacement forit. All activities that are to be performed in your cabinet should first be approved by a competentprofessional, such as an industrial hygienist or safety officer. This will ensure the cabinet is appropriate forthe work it will be required to do. A competent professional should monitor the cabinet and its operatingpersonnel at regular intervals to see that it is being used correctly.Operator Controls:The operator controls and indicators are arranged on the front panel of the unit.Blower On / Off Switch –This push button is a maintained action switch that controls the power to the cabinet blowers.Pressing and releasing the push button from the UP/OFF position will change the switch to theDOWN/ON position. The cabinet blowers will start. The GREEN indicator in the push button willilluminate. Pressing and releasing the push button from the DOWN/ON position will change the switchto the UP/OFF position.Caution:The cabinet audible alarm is disabled when the Blower switch is in the OFF positionLight On / Off Switch –This push button is a maintained action switch that controls the power to the cabinet fluorescentlights. Pressing and releasing the pushbutton from the UP/OFF position will change the switch to theDOWN/ON position. The cabinet lights will illuminate. The GREEN indicator in the pushbutton willilluminate. Pressing and releasing the pushbutton from the DOWN/ON position will change the switch tothe UP/OFF position.Mute switch -This push button is a momentary action switch that temporarily mutes the audible alarm. A timermodule inside the canopy controls the length of time that the alarm is muted. This is set at 5 minutes as afactory default but can be changed to 1 second to 100 hours. It may be desirable to increase this settingwhen cabinet decontamination is being performed. The YELLOW indicator in the push button willilluminate while the alarm mute function is active. Should the alarm condition be remedied before themute ‘times-out’ the timer will be reset and the mute indicator will not be illuminated.Page 7 of 54

Left Side & Right Side Outlet On / Off –A separate 10 amp circuit breaker/switch is supplied for the remote switching of power to the rightand left outlet receptacle located inside the BIOPROtect II .The breaker switches will ‘trip’ if the totalelectrical load on the circuit exceeds 10 amps.Ground Fault Circuit InterrupterGround fault circuit interrupter (GFCI) outlets are installed on the 120V power circuit on this cabinet.The GFCI is designed to protect the operator from a possible electrical ground fault hazard. If ahazardous condition exists the GFCI will cut off electricity to the outlet. The button in the center of theunit will pop out. If the GFCI “trips” you should first determine and correct the cause of the problem,then press the button to reset the GFCI.Air Pressure AlarmThe Air pressure alarm is controlled by a Modus Air Pressure indicator mounted in the controlcanopy. Operating & set up instructions for this instrument can be found in the On-Site Checks AndMaintenance section of this manual. When either a High or Low flow condition is present for more than3 seconds the audible alarm will be activated. Pressing the Mute switch will silence the alarm. The mutetime is determined by the setting of a timer inside the control canopy. Factory setting of this timer is 5minutes. Consult the test report for your cabinet for the factory set flow conditions for this alarm. TheBaker Company recommends continuous operation to keep the interior work space clean and free ofunwanted particles.Caution: The cabinet audible alarm is disabled when the Blower switch is in the OFF positionThis feature allows the user to turn-off the cabinet blowers when no longer required and the processeswithin the cabinet are found to be safe to personnel and the environment.Caution: It is recommended that prior to turning the Blower OFF you contact your health and safety officer fordecontamination procedures.Also refer to section 2 “Decontamination”Page 8 of 54

Door OperationsDuring cabinet operation, the only access that should be permitted is through the 8” sash openingsprovided at the front of the cabinet. For set-up purposes, the viewscreen or the large front doors can beopened to provide greater access.To open the viewscreen:Caution: Failure to latch the viewscreen in the open position may result in injuryGrasp the acrylic panel and pull it away from the door to disengage the two grab catches on each side ofthe viewscreen.Swing the panel up to engage the support brackets on the cabinet’s top section.You must reach up andswing the two securing latches down to constrain the viewscreen in the open position.To open the door:Open the viewscreen in the right hand door and disengage the upper door pawls. They are located in thecenter of the unit inside of both doors. Return the viewscreen to the closed position.With the viewscreen in the closed position, slide the dead bolt to the right to disengage the slide from theleft door receiver. The deadbolt is located just inside the right door and mates with a receiver located onthe inside of the left door.Pull the doors open. Due to the cam rise action of the hinges the doors will self close if left open. Swingthe doors 100 degrees (slightly more than perpendicular to the front of the cabinet) in order to overridethe self closing feature.Removing the cartCaution: It is recommended that prior to cart removal you contact your health and safetyofficer for decontamination procedures Also refer to section 2 of this manual “Decontamination”.Should it be necessary to remove the cart, you must open the front doors to fully expose the BIOPROtectII’s interior work bay. This area is assumed to have contamination so use caution in the way you approachthe task.1. Decontaminate and clean the unit as recommended by your health and safety officer.2. Open the doors to expose the cabinet’s work bay.3. Any equipment on the cart should be disconnected from the side wall service connections andremoved from the iris ports.4. Unlock the front casters by pulling up the foot operated locking devices. When the locking device isin a horizontal position it is unlocked.5. Use the hand crank to lower the height of the work surface if necessary. Check that your equipmentwill clear the front header if it is allowed to be left on the cart.6. Pull the cart out and away from the BIOPROtect II. The casters provided are swivel and all arelocking.Page 9 of 54

Set-up ProcedureThis section outlines the tasks required to properly install automated laboratory work stations withinthe BIOPROtect II. This does not replace the recommendations of the equipment manufacturer. It isassumed that the user is familiar with the set-up and operation of the ancillary equipment.Place the equipment on the cart’s table top so that the equipment is within the area of the table top asdefined by the four corners. The front of the equipment must face the front of the cart (crank handleside).Using the crank handle provided on the cart, adjust the cart’s height until the work table of the equipmentis flush or below the intake grill section of the doors. Stow the crank handle under the work table.Make utility connections to the side wall services.Close the front doors of the BIOPROtect II and make certain that you can perform any manual operationson the equipment through the 8” x 42” sash openings provided.Make certain that no part of the equipment blocks or hangs over the front intake grilles.Power and run all equipment. Make certain that the equipment and cabinet is operating properly and thatnone of the BIOPROtect II’s circuit breakers have ‘tripped’.Have a certifier or safety officer witness the air currents (using a smoke tracer) to determine that theequipment does not compromise the cabinet’s ability to provide personnel and product protection. Theuser may choose to use a particle counter to evaluate the product protection capacity of the cabinet. Ameasurement of the personnel protection capacity of the cabinet (containment), should the user deem itnecessary, will be a more involved test and will require a third party skilled in the operation of the BIOanalogtest or the KI-discus test.Page 10 of 54

Start-up procedure1. If the unit has not been left running continuously, press the blower on/off switch. The switch will beilluminated when switched on. The cabinet’s audible alarm may activate for several seconds untilthe blowers have come up to full speed. Make sure that you have cabinet airflow, either by listeningfor blower sounds or feeling the airflow across your fingers. Check the reading on the air pressuregauge. The reading on the gauge should be consistent with the last time the unit was on.2. Turn on the fluorescent lights.The switch will become illuminated in the ‘on’ position and thefluorescent bulbs should activate.3. Wipe down the interior area of the cabinet with a surface disinfectant.NOTES:Some disinfectants may corrode or stain the steel surfaces. If this happens, clean thesurfaces afterward with a disinfectant-detergent and rinse with sterile tap water to preventcorrosion.Blocking the front and rear perforated grills must be avoided. If wipes or absorbenttowels are used on the work surface, be sure to keep them away from the grills.Check that the position of the rear wall dampers (three upper and three lower) are consistent with thesettings from the factory test report.After your equipment is in place inside the cabinet, close and secure the doors. All operations insidethe BIOPROtect II must be carried out through the unit’s 8” sash openings.Caution: The BIOPROtect II will not provide adequate personnel protection unless the front doors andviewscreens are closed.4. After a procedure has been completed, all equipment which has been in contact with the researchagent should be enclosed, and the entire surface decontaminated.Trays of discarded items should becovered. The cabinet should then be allowed to run for at least three minutes with no activity so thatthe airborne contaminant will be purged from the work area.5. After you have removed all materials, culture apparatus, etc., decontamination of the interiorsurfaces should be repeated.Check the work area carefully for spilled or splashed nutrient whichmight support bacterial growth. And never use the cabinet to store supplies or laboratory equipment.Page 11 of 54

Reacting to SpillsCaution: An Emergency spill containment and clean-up procedure should be establishedprior to an accidentSpilled fluid on the floor of the BIOPROtect II is contained within the stainless steel work area of thecabinet via the threshold placed under the unit’s door. The threshold will contain a volume of approximately2 gallons (6 liters) of fluid. However, because the BIOPROtect II cabinet bears directly on the users floorthere is no drain provided.1. It is recommended that the researchers, in coordination with their consulting safety professional,have a written plan available in case of an accidental exposure or spill.2. In the case of biological spill, for example, the area containing the spill may be flooded with anappropriate disinfectant. After the disinfectant has had time for a complete kill, remove the residue.If you have used a disinfectant which is harmful to stainless steel (Hypochlorite bleach solutions, forexample) be sure that none remains to corrode cabinet surfaces. Clean the surfaces with sterilewater.3. The Center for Disease Control has published “Biosafety in Microbiological and BiomedicalLaboratories.” If you have a spill involving a hazardous Biosafety Level 2 or 3 agent, then you areadvised to leave the cabinet running so as to let the aerosols settle before you start cleanupprocedures. With some spills, it may be necessary to decontaminate the room with an agent such asformaldehyde gas. (Biosafety Level 4 agents should never be used in the type of cabinet.)4. If the spill contains volatile liquids which generate vapors creating a danger of fire or explosion, turnoff the unit and other electrical equipment. Evacuate and seal the room and call for immediate helpfrom a safety professional.5. If the agent is a hazardous chemical, it may be recommended that a Spill Kit be kept readilyavailable. This kit should be clearly labeled, and might include such items as a respirator, chemicalsplash goggles, two pairs of gloves, two sheets of absorbent material, spill control pillows, a solutionto clean the contaminant, and waste disposal bags or other containers. Consult your safetyprofessional for proper procedures and treatment of the specific agents you plan to use.Page 12 of 54

DecontaminationWhenever maintenance, service or repairs are needed in a contaminated area of your cabinet, the unitmust first be decontaminated by an appropriate agent. The National Institute of Health, National CancerInstitute and the Center for Disease Control have all recommended the use of formaldehyde gas for mostmicrobiological agents. Its application requires individuals who are experienced in the decontamination ofcabinets, since the gas itself is toxic. Consult the NSF/ ANSI-standard-49-2002 Annex G for details andprocedures on the decontamination of Biological Safety cabinets.Whatever gas you choose, have the proper safety equipment (gas masks, protective clothing, etc.) withineasy reach. In addition, you will want to be sure that the gas you are using will be effective against all of thebiological agents within the cabinet. When you have decided which gas to use, post the antidote to it in avisible and nearby location.The volume of the BIOPROtect II cabinet is approximately 150 cubic feet, this will help you determinethe required amount of decontaminating gas.Carcinogens present a unique chemical deactivation problem and the standard biological decontaminationwill not be effective against chemicals or other non-biologic materials. With materials of this kind, consult aqualified safety professional.Warning! This procedure should be performed by qualified technicians only.Decontamination procedureSurface-disinfect the inside of the windows and all other surfaces on the viewscreen assemblys.Multiply the total volume of the cabinet (150 ft 3 ) by .3 gram/ft 3 ) to determine the amount ofparaformaldehyde required to decontaminate the cabinet. If the cabinet is vented to the outside you mustconsider the volume of the duct work in the paraformaldehyde calculation.Prior to sealing up the cabinet make sure all gas or flammable petcocks are closed and pressure tight.The inside cabinet work space must be at room temperature with 60% to 85% relative humidity. If relativehumidity is low (below 60%) add boiling water in the work space. Monitor the inside of the cabinet with ahumidity meter. Relatively humidity above 85% will require extra clean up which will be covered in step 15.Note:Without the proper relative humidity the formaldehyde gas will not be effective. The mode of entry offormaldehyde into the living organisms is through the cell wall by the absorption of water.Place a heating mantle with paraformaldehyde in the work space. The heating mantle must be able to reach450 degrees F and must have a grounded plug which should be plugged in to an outlet outside the cabinet.Place a second heating mantle in the cabinet with 60% more by weight of ammonium bicarbonate and 10%more if using ammonium carbonate, than paraformaldehyde. This will be used later in step 13 to neutralizethe formaldehyde gas.This step is recommended. Place spore strips inside the cabinet to confirm the decontamination process hasbeen successful.If the cabinet is vented to the room, use a sheet of plastic and seal the front access and exhaust port openings.These openings should be sealed such that the exhaust airflow recirculates back to the front access opening.This will promote the even distribution of formaldehyde gas throughout the cabinet.Page 13 of 54

If the cabinet is vented to the outside, then the exhaust transition should have a means to recirculate theexhaust airflow back to the cabinet blower if possible. This will promote the even distribution offormaldehyde gas through the exhaust filter. Seal the front access opening.Turn on the heating mantle containing the paraformaldehyde flakes.After 25% of the paraformaldehyde has depolymerized, turn on the cabinet blower for 10 to 15 seconds.Repeat after 50%, 75% and 100% of the paraformaldehyde has depolymerized, approx. 20 to 30 mins..Allow the formaldehyde gas a minimum residence time of 6 hours, preferably over night.Turn on the heating mantle containing ammonium bicarbonate (NH4HCO3). After 25% of the ammoniumbicarbonate has depolymerized turn on the cabinet blower for 10 to 15 seconds. Repeat after 50%, 75% and100% of the chemical has depolymerized to neutralize the formaldehyde. Turn on the cabinet blower andallow the two gases to circulate for at least one hour.Check for formaldehyde by using a gas sampling device (dregger tube) to be sure the formaldehyde is at asafe level inside the lab space.Cut open the plastic and vent the cabinet to the outside.Aseptically remove spore strip and place in Trypticase-soy broth and incubate for 7 days. No growth willverify the decontamination process.When cleaning up, you may find residual paraformaldehyde (white powder) on the metal or glass surfaces.To remove this, use ammonia in warm water, wear gloves and wipe down the affected surfaces. Theparaformaldehyde will dissolve in water and be neutralized by the ammonia.Page 14 of 54

About the HEPA FiltersThe HEPA filter is one of the essential components of a biological safety cabinet. It is the shield whichstands between the environment and the experimental agent. Some questions that the user should askregarding the use of chemical agents in the BIOPROtect II are as follows:1. Are these chemicals, either singly or in combination, able to attack filter components?2. Are these chemicals potentially toxic to the operator? Is there any combination of two or morewhich could be toxic? If the cabinet is being correctly used and only the operator’s hands and armsare inside the machine, then toxicity or irritation could occur through skin penetration. A properevaluation of toxicity must deal not only with onetime exposure, but also with the effect of manysmall exposures over a period of time.3. Are these chemicals explosive or flammable? If so, they should never be used in your cabinet. Witha buildup caused by recirculation of air, an explosion can be the result of a motor spark or a burneroperation in the work area.4. In cases where chemical carcinogens, mutagens or teratogens are to be used, the risks should becarefully weighed in choosing a cabinet. Where the exhaust effluent contains a contaminant, it mayneed treatment.5. The life of a filter is determined by how it is used and how often. Under normal laboratoryconditions, you can expect up to five years of use. However, misuse or a heavy dust load within thecabinet will shorten any filter’s lifetime. Bunsen burners and misuse of chemicals will also shortenthe useful life.Page 15 of 54

IV - ON-SITE CHECKS AND MAINTENANCE PROCEDURESWe recommend that the filter leak checks be performed before initial use, after relocation and after eachfilter change.They should also be carried out at regular intervals, usually six months or one year, as specifiedby an industrial hygienist, safety officer or other qualified person.As reported earlier in this manual, each individual cabinet made by The Baker Company is carefullytested before it leaves the factory.Your copy of the test report, which you will find at the back of this manual,gives the factory test results for your BIOPROtect II cabinet.Use it as your record of the original testing, and as your guide to testing in the future.To gain many yearsof satisfactory service, please be sure that your maintenance personnel come as close as possible toduplicating these original test figures. Your test procedures should be identical to ours so that comparing testresults will have meaning. Please correspond directly with us to request detailed procedures for yourparticular cabinet model.Filter Media and Seal Leak TestsWhen preparing your cabinet for use after shipment, and then at prescribed intervals throughout itsworking life, you will need to verify that the filters have maintained their integrity.This is done by scantesting the filter faces and seals.The Institute of Environmental Sciences recommended practice IES-RP-CC034.1 would be a good reference for this testing.The equipment needed will be:• An aerosol photometer. The instrument should sample air at a flow rate of 1 CFM.•• A (D.O.P) generator with Laskin nozzle(s). Liquid dioctylphthalate (DOP), dioctylsebacate orcomparable substance aerosolized by flowing air through the nozzle(s).When generated withLaskin type nozzle(s), the mean droplet size of the aerosol is 0.1 –3.0 micron with an average of0.45 micron.Page 16 of 54

Procedure for filter leak tests1. Decontaminate the cabinet in accordance with NSF/ANSI standard-49-2002 and your health andsafety officer.2. Remove the front upper panels by first removing the ¼-20 hardware. Remove the damper from thefront of the filter. This will expose the exhaust filter.3. Find the 1/8” NPT hose barb on the top of the cabinet used for measuring the upstreamconcentration of challenge.4. Turn on the aerosol photometer and set-up according to the manufacturer's instructions.5. With the cabinet’s blowers running, position the D.O.P. generator so as to introduce air generatedsmoke into any of the work bay openings (side wall to door openings or rear wall openings are allappropriate for introducing challenge). Measure the upstream concentration of the challenge. Youmust have a concentration of at lease 10 micrograms per liter.6. Supply Filter: Remove the diffuser prior to scanning the filter. Holding the photometer probe nomore than one inch from the filter face scan the entire surface area and perimeter (filter gasket framearea) in slightly overlapping strokes at a traverse rate of not more than ten feet per minute.7. Exhaust filter: You may scan the downstream face of the exhaust filter from outside of the cabinet.8. Eliminate leaks in the gasket frame area by re-tightening the filter gasket.9. An unacceptable leak is defined as a reading greater than 0.01%Page 17 of 54

The Airflow Balance! Warning !This procedure should be performed by qualified technicians only.The airflow balance which is set at the factory provides your unit with the air volume and velocity controlto minimize leakage or airborne contamination either in or out of the work area.In order to duplicate as closely as possible the airflow characteristics described in the original factory testreport, please follow these steps:1. Make certain that the front doors and viewscreens are closed and secured so as to make two 8” x 42”horizontal access openings.2. Using a DIM (Direct Intake Measurement) on each 8” X 42” horizontal access opening at the same time,measure the flow rate into each of the front access openings. Take at least five (5) consecutive readings perside. Average the readings and divide by 2.3 square feet (area of each front access opening). Acceptablerange of the average shall be 100-110 FPM.3. Using a hot wire anemometer mounted on a ring stand within the work area, take readings with theanemometer probe set 6” below the diffuser. The location of these readings should be the same as shown inthe factory test report. The average of these velocity readings must be in the range between 50 and 70 FPM.4. After you have compared your figures with those originally taken at the factory, make whateveradjustments are necessary. Use the motor speed controls and the exhaust dampers to bring the intake anddownflow average values within the specifications.! Warning !When the light canopy is lowered, some electrical parts are exposed. Do not perform this work unless you are aqualified and trained electrician or electrical technician.! Warning !Terminals M1 and M2 as well as L1 and L2 are High Voltage5. As the HEPA filters load up with particulates, airflow will be maintained automatically to some extent.When the air flow is diminished you will have to increase the motor speeds to maintain the specified intakeand downflow velocity averages. This is done via the speed controllers located in the light canopy.On the speed controller, turn the potentiometer clockwise until you have the desired airflow. Use avoltmeter to check the voltage across terminals M1 & M2. This is the voltage out to the motor. If the airflowcannot be maintained, it will necessary to replace the HEPA filters.(See “Procedure for HEPA Filter Replacement” later in this section.).Page 18 of 54

Airflow Smoke Pattern TestAirflow smoke patterns have been shown to vary depending on the equipment that is used inside thecabinet. The BIOPROtect II has been tested with the cart only. A description of this testing is summarized inthe test report. However, when the BIOPROtect II is set-up properly (i.e. your set-up should not block orrestrict the grilles and diffusers provided) the appearance of the airflow directly at the 8” access openingsmust be consistent with that described in the test report.To check for the direction of air movement, use a smoke generator and trace along the front accessopening on the inside of the cabinet. Observe that no smoke is escaping from the work area.In order to be sure that room air is not entering the work area, trace along the outside of the front accessopening. Observe that no smoke penetrates to the work surface.Grounding Continuity TestUsing an Ohmmeter, set it to read the low resistance scale.Touch the two leads together and see that thedisplay reads 0.1Ω to 0.0Ω. Touch one lead to the ground lug on the cabinet power cord while touching theother lead to bare metal on the unit where the user would be likely to touch the cabinet. According to NSF/ANCI-standard 49-2202 the maximum allowable shall be 0.15Ω (Max allowable for UL is 0.50Ω ).Page 19 of 54

Calibration procedure for Modus Airflow alarm(Digital Differential Pressure Monitor).Note: This procedure MUST be followed every time the damper width has been changed.Initial Set Point SettingsBalance the cabinet air flows to nominal operating set point per manufacturer instruction.( Seeinstruction label on front of cabinet).Record voltage to motor/blower (M1, M2 on speed control) and measure and record damper/ slotwidthMake certain that the Modus displays 0.000 when zero pressure is applied(This can be easilyaccomplished by removing the Tygon tubing from the hose barb fitting). Use the “zero” function ifnecessary.Re-connect the tygon tubing and make sure that the value displayed is negative(-) when the cabinet isrunning.Low Flow Alarm SettingPlace a DIM airflow hood on the front of the cabinet or use the 3 inch method for measuring inflow.Adjust cabinet to a 20% reduction in airflow by decreasing the voltage to motor. DO NOT adjust thedamperRecord the exhaust/ damper pressure on Modus (indication of exhaust plenum pressure at20% reduction) and voltage to motor/ blower (across M1, M2 on speed control)Set the Modus High Alarm set point to the 20% reduction in pressure recorded in step 14 (per Modusprogramming instructions below)Set the Modus dead band to .002 (per Modus programming instructions below).Return cabinet to Nominal Set Point voltage, recorded in step 2Check the CalibrationSet Point CheckWhile measuring the intake airflow with a DIM, reduce the airflow by decreasing the voltage tomotor/ blower until a 20% reduction in flow is measured. Check that the low set point alarms at thisvalue. If not, reset Modus low alarm set point to alarm as desired, per instructions. Return cabinetto Set Point Voltage.Page 20 of 54

Modus Programming Instructions1.) Programming the Alarm Set pointsAfter the first press of MODE, the HI LED flashes, indicating the HI set point is being entered. Theleast significant digit (right hand) should be flashing. Press the ARROW key to scroll to thedesired digit (0 through 9). Press the MODE to move towards the most significant digit and press theARROW key set each remaining digit’s value. The sign of the set point (+ or -) is selected last.After the HI set point has been programmed, press the MODE to enter the LO set point. The LOalarm LED flashes, and you can repeat the above process to program the LO set point.2.) Programming the Relay Dead bandThe dead band selection is provided to keep the relays from chattering when the pressure varies nearthe set point. To display the dead band, press MODE once after setting the LO set point polarity inthe previous step. Both alarm LEDs flash. The three digits displayed are the dead band width, in thesame units used for data display. Press the MODE and ARROW keys as described earlier to set thedead band to a value of .002.3.) Returning to Normal OperationPress MODE once after the setting the dead band parameters. The digit “1” on the left indicates theunit is in analog setting mode. Since there are no analog outputs, the MODE key can be pressed afinal time to end programming and return to the normal pressure display.Page 21 of 54

Maintenance NotesWARNING!Before any panels are removed, the cabinet must be decontaminated.Also see section 2 “Decontamination”The filters are sure to have collected microorganisms and other potentially harmful particles generated from thework area during their lifespan. Maintenance personnel should not allow themselves to be exposed.It should also be remembered that a specific gaseous decontaminant may work against microorganisms, butnot against chemical agents. Where chemical agents are present, consult an industrial hygienist or other qualifiedperson(s).Replacing the HEPA FilterIf the differential pressure monitor presents an alarm, or if your periodic checks of total airflow show adrop of more than 5% of the nominal set point, the filters may be loading with particulates. As explainedearlier in this section, the blower speed can be manually increased to compensate for filter loading.However, when the airflow can no longer be maintained or when the filters are damaged, they need to bereplaced.A contaminated filter must be handled with caution. Personnel should be protected by clothing orbreathing apparatus as necessary to the nature of the hazard. It is advisable to seal the contaminated side ofthe filter by taping a plastic sheet or cardboard over the face before removal. This should minimize thenumber of particles shaken loose from the filter. Once removed, the filter should immediately be sealed in abiological hazard bag and then disposed of safely in accordance with environmental regulations.After filter replacement has been completed, the cabinet and the room should be cleaned anddecontaminated in a manner consistent with the nature of the hazardous material. The cleaning materials,along with the protective gear and clothing, should be properly disposed of.HEPA filters are very easily damaged, and you will want to use great care during handling so as to avoidinjury to the filter media and gasket surface. When installing the new filters, it is a good idea to tape a pieceof cardboard over the filter media to give protection against dropped wrenches or misdirected fingers. Ofcourse, you will need to make sure that the cardboard is removed before the access panels are re-installed.Inspect the filters carefully before and after installation. A broken or damaged filter is worthless.Changing the Exhaust FilterThe BIOPROtect II requires two exhaust filters measuring 19” x 38” x 12” deep (consult test reportfor part numbers and specifications).These filters are arranged to face the front of the unit so as toeliminate the nuisance of ceiling restrictions on the exhaust air.To service the exhaust filter remove the panels from the front of the unit using a 3/8” nut driver orsocket to remove the ¼-20 hardware. Using the same 3/8” driver, remove the hardware from the filtersecuring frame. Pull the frame and filter away from the unit.Prepare the new filters by putting a light coat of silicone grease on the face of the gasket. Clean thesealing flange thoroughly. Then carefully slide the new filter into place and make sure that it is properlyseated on the flange. Replace the filter clamp assembly and perform the leak test described earlier in thischapter.Page 22 of 54

Changing the Supply FilterThe BIOPROtect II requires two supply filters measuring 32” x 45” x 3” deep (consult test report forpart numbers and specifications). These filters are arranged so as to be serviced from inside theBIOPROtect II work area. Consequently you will have to remove the cart and any equipment from insidethe cabinet prior to changing the filters.To service the supply filters first swing the diffusers down allowing them to rest on the rear wall byremoving the ¼-20 screws at the front edge of the diffuser panel. Next using a 3/8” driver remove the ¼-20 hardware that secures the frame to the filter. This frame supports the filter.Prepare the new filters by putting a light coat of silicone grease on the face of the gasket. Clean thesealing flange thoroughly. Place the new filter in the center of the frame and install the frame into thecabinet using the ¼-20 hardware.Conduct a filter leak check as described in the earlier chapter.Page 23 of 54

V. - TROUBLE SHOOTINGHere are some suggestions based on our experience with the use and misuse of biological safetycabinets.CAUTION:Whenever the potentially contaminated areas of your cabinet must be entered, make sure that the unit is firstdecontaminated by use of an appropriate method by qualified personnel.Also see section 2 “Decontamination”When a smoke test indicates that there is air flowing from the interior of your cabinet into thesurrounding room:1. Make certain that the front doors are closed and the front intake grilles are not blocked. This willcreate 8”x 42” horizontal openings in the front of the cabinet.2. If your cabinet is connected to an in-house exhaust, make sure that there is adequate exhaust suctionand no back pressure. Also, be sure the dampers are open. Re-balance the exhaust system to handlean adequate quantity of air and static pressure (suction). Consult with building maintenance people.3. The exhaust filter may be loaded with dirt if the unit has been in service for some time.Decontaminate, and replace the HEPA filter.4. There may be high cross-drafts in the room which are causing the outflow of smoke. Check theairflow balance, following the procedure recommended in an earlier section of this chapter.Eliminate the source of the cross-draft.If there is no airflow within the work area:1. Make sure that the blower switch is turned on. The indicator on the push button should beilluminated.2. If the lights are working, then turn the blower switch off and let the cabinet rest for ten minutes.When the time has passed, turn the blower switch on again. If the blowers start, you know there hasbeen overheating of the blower motor(s).Also check the wiring connections inside of the lightcanopy which connects the canopy to the cabinet. Be sure the connections are pushed together.3. If these solutions do not correct the problem, or if the blowers failed to start after the rest period,then either the speed control, blower motor(s) or capacitor is defective. A qualified electrician canfind out if the speed control is defective by bypassing it, using the wiring diagram in the Appendixof this manual as a guide. If there is a noise problem, it may be caused by motor bearings.When there is uneven fan operation, or noise from the motor/blower assembly:1. It may be necessary to decontaminate the cabinet.2. Look for loose objects in the fan cage.3. Check to see if the fan wheel is contacting the blower housing.4. Open the light canopy and check the multi-pin connectors at each end to be sure they are securelyengaged.5. Another possible source of the problem is the speed control.Page 24 of 54

If the fluorescent light does not work -1. Make sure that the light switch is turned on.The indicator on the pushbutton should be illuminated.2. Make certain that the bulbs are installed properly into the clips.3. Open the light canopy and check the multi-pin connectors at each end to be sure they are securelyengaged. If the lamp flickers, there is probably an improper ground.The wiring can be traced to thesource of a break.Page 25 of 54

REPLACEMENT PARTS LISTPART NAMEQTYBAKER COMPANYPART NUMBERBlowers 2 11432Capacitor 2 11558Motor (220 V, ½ HP, 1620 RPM) 2 11629Filter, exhaust, 19” x 38” x 12” 2 41175Filter, supply, 32” x 45” x 3” 2 38913Power Supply, 24V DC, 1A 1 39324Motor speed control 2 39658Fluorescent lamp 4 17927Ballast, fluorescent 2 34160Pressure Monitor/Alarm 1 38996Hydraulic pump kit (cart) 1 40187NOTE:When ordering replacement parts, please furnish serial number and model number of unitPage 26 of 54

VI. APPENDIXPage 27 of 54

Modus Installation and Operation HandbookPage 28 of 54

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BGA-BIOPROtect II Vent to Room Page 1Page 42 of 54

BGA-BIOPROtect II Vent to Room Page 2Page 43 of 54

BGA-BIOPROtect II Vent to Room Page 3Page 44 of 54

BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 1Page 45 of 54

BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 2Page 46 of 54

BGA-BIOPROtect II-19 Hard Exhaust Connection(HEC) Page 3Page 47 of 54

BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 1Page 48 of 54

BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 2Page 49 of 54

BGA-BIOPROtect II-20 Canopy Exhaust Connection (CEC) Page 3Page 50 of 54

BGA-BIOPROtect II Optional CartPage 51 of 54

Wiring Diagram-Standard BIOPROtect IIPage 52 of 54

Wiring Diagram – Master BIOPROtect IIPage 53 of 54

WARRANTYThe Baker Company, Inc. expressly represents and warrants all goods (a) to be as specified in the BakerCompany catalogs and literature, and (b) to be free under normal use, service and testing (all as described inthe Baker Company catalogs and literature) from defects in material and workmanship for a period of twelvemonths from the invoice date.The exclusive remedy for any breach or violation of this warranty is as follows: The Baker Company,Inc. will, F.O.B. Sanford, Maine furnish without charge repairs to or replacement of the parts or equipmentwhich proved defective in material or workmanship. No claim may be made for any incidental orconsequential damages.This warranty is expressly in lieu of all other warranties, express or implied, including any impliedwarranty of merchantability or fitness for a particular purpose, unless otherwise agreed in writingsigned by the Baker Company. (The Baker Company shall not be responsible for any improper use,installation, service, or testing of the goods).Page 54 of 54