Screening for Delirium, Dementia and Depression in Older Adults

Nursing Best Practice GuidelineMedications That May Cause Cognitive Impairments (con’t)Type of medication Generic name Common trade name(s)Antineoplastic agents chlorambucil LeukerancytarabineCytosar-Uinterleukin-2spirohydantoin mustard SpiromustineAnticonvulsants phenytoin Dilantinvalproic acidDepakene, DepakotecarbamazepineTegretolAnti-Parkinsonian agents levodopa Larodopa Sinemet Parlodel Permax(see also anticholinergic agents) levodopa/carbidopabromocryptine pergolideAntiemetics prochlorperazine Compazinemetoclopramide ReglanhydroxyzineAtarax, VistarilpromethazinePhenergantrimethobenzamide Tigandiphenhydramine Benadryl, DramaminemeclazineAntivertSkeletal muscle relaxants cyclobenzaprine FlexarilmethocarbimolRobaxincarisoprodolSoma, Soma Compound [b]baclofenLioresalchlorzoxazoneParafon Forte, ParaflexAntihistamines/decongestants diphenhydramine Benadryl, Tylenol PM [c], Sominex,other OTC cough/cold preparationschlorpheniramine Chlor-Trimeton, Deconamine [c], Contac [c],Tylenol Cold [c], Hycomine [c], other OTCcough/cold preparations [c]brompheniramine Dimetane, Dimetapp[c], Drixoral[c], otherOTC cough/cold preparations[c]pseudoephedrine Sudafed[c], Actifed [c], Robitussin PE [c],Dimetapp [c], Entex [c], Drixoral [c],Tylenol Cold [c], Claritin-D [c], other OTCcough/cold preparations [c]phenylpropanolamine Ornade [c], Triaminic [c], Poly-Histine [c],Hycomine [c], other OTC suppresantpreparations [c]83Reprinted with permission.Source: Costa, P. T. Jr., Williams, T. F., Somerfield, M., et al. Recognition and Initial Assessment of Alzheimer’s Disease andRelated Dementias. Clinical Practice Guideline No. 19. Rockville, MD: U. S. Department of Health and Human Services,Agency for Healthcare Policy and Research. AHCPR Publication No. 97-0702. November 1996.