LC/MS/MS Analysis of Gabapentin, Benzodiazepines, and Opiates

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Extracted Spiked Plasma Benzo MRMChromatograms (10 ng/mL)Benzo resultsOpiates MethodExtracted Spiked Plasma Opiate MRMChromatograms (50ng/mL)Mobile Phase: 0.1% Formicaq/MeOHNebulizer Gas: N 2 @ 30psiDrying gas: N 2 @ 24psi (350C)Flow rate: 200 uL/minColumn: MetaChem Taxil 100 x2mm 3um
Opiate resultsCustom ReportsBenzodiazepine and OpiatesSummaryExcellent sensitivityQuantitation limits will be below 10ng/mL (50ng for Opiates)Excellent quantitation can be achieved using a select fewinternal standardsBoth LC programs have a 15 minute run time.The additional sensitivity of 320ms allows for three ionmonitoring of each analyte.Analysis of Amphetamines byLC/MS/MS
Page 1 and 2: Presentation OutlineLC/MS/MS Analys
Page 3 and 4: MSMS Using a Curved Collision CellI
Page 5 and 6: Analysis of Gabapentin byLC/MS/MSWh
Page 7 and 8: Introduction to BenzodiazepinesAnal
Page 9: 320-MS LC SystemsBreakdown CurvesHy
Page 13 and 14: Amphetamine Summary Excellent sensi

LC/MS/MS Analysis of Gabapentin, Benzodiazepines, and Opiates

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