A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

Hamster 1 1500 mg/kg IP 2Hamster 2380 mg/kg IP with α-chloralose 38 mg/kg IP andpentobarbital 2.6 mg/kg IP 2Rabbit 1 1000 mg/kg IV, IP 37 Surgical anesthesia 177Rabbit 21000-1300 mg/kg IV with acetylpromazine 2.0 mg/kgIM 132 SedationRabbit 3 1500 mg/kg IV 80Rat 1 1000-1200 mg/kg IP 2 Surgical anesthesia 177Rat 2 500-800 mg/kg IP then α-chloralose, 60 mg/kg IP 15minutes later 132Dosage frequencyGuinea Pig 360-480 minutes 177Hamster 1 360-480 mginutes 177Ferret 4-6 hours 220Rabbit 1 360-480 minutes 177Rabbit 213-23 hoursRat 1 >24 hours 67, 103 360-480 minutes 177Rat 2 21 hours 132CommentsAllCarcinogen. Only for nonsurvival surgery.Rat 1 Good anesthesia reported 103VECURONIUM (Norcuron)Class Nondepolarizing neuromuscular blocking agentSource OrganonCat56, 21625-35 µg/kg IVDog 1 0.1 mg/kg. Route not indicated 37 IV 50Dog 2 0.014 (ED 90 ) 216Primate 1 0.04-0.06 mg/kg IV 219Primate 2 0.4 µg/kg/min IV 219RabbitSee PropofolRat 1 1.5 mg/kg IV 97Rat 2 0.45 mg/kg IV 216Sheep56, 2164.6 µg/kg IVSwine 1 0.5 mg/kg for intubation. Route not indicated 37Swine 2 0.2 mg/kg IV, maintain at 0.3 mg/kg/hour IV 199Swine 3 1.0 mg/kg IV 240Dosage frequencyCat 5-9 minutesDog 1 42 minutes 56Rat 1 10 minutes 97Sheep56, 21614 minutes56, 216