A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

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Dog 1 0.125 mg/kg IV with 4-aminopyridine 0.3 mg/kg IV 45Dog 2 0.11 mg/kg IV slowly 72Ferret 1 0.1 mg/kg SC, IM 130Ferret 2 0.5 mg/kg IM to reverse xylazine 232Goat45, 1350.125 mg/kg IVMouse 0.2 mg/kg IP 234Rabbit 1 0.2 mg/kg IV 36 IM 40Rabbit 2 0.2-1.0 mg/kg IM, IV 233Rat 1 2.1 mg/kg IV for ketamine/xylazine combination 45Rat 2 0.2 mg/kg PI 234Sheep45, 1350.125 mg/kg IVSwine 1 0.125 mg/kg IV 75Swine 2 1.0 mg/kg IV 221CommentsAllAdminister slowly intravenouslyGoat May be ineffective in sheep 135Rabbit 1Mild reversal. Decreases arousal time.Sheep May be ineffective in sheep 135
References1. Bacher, J. Primate Anesthesia. Anesthesia and Analgesia in Laboratory Animals.Proceedings, 1990 Forum of the American College of Laboratory Animal Medicine.Columbia, MD.2. Sawyer, D. Use of Analgesics for Postsurgical Pain in Dogs and Cats. In: Anesthesia andAnalgesia in Laboratory Animals. Proceedings of the 1990 Forum of the American Collegeof Laboratory Animal Medicine. Columbia, MD.3. Wixson, S. Current Trends in Rodent Anesthesia and Analgesia. In: Anesthesia andAnalgesia in Laboratory Animals. Proceedings of the 1990 Forum of the American college ofLaboratory Animal Medicine. Columbia, MD.4. Swindle, M. Anesthesia & Analgesia in Swine. In: Anesthesia and Analgesia in LaboratoryAnimals. Proceedings of the 1990 Forum of the American college of Laboratory AnimalMedicine. Columbia, MD.5. Hobbs, B. Anesthetics and Analgesics in Rabbits. In: Anesthesia and Analgesia inLaboratory Animals. Proceedings of the 1990 Forum of the American College of LaboratoryAnimal Medicine. Columbia, MD.6. Sawyer, D., Evans, A., DeYoung, D., and Brunson. Anesthetic Principles and Techniques.6 th edition. Michigan State University Press, 1981.7. Hughes, H. and Lang, C. Control of Pain in Dogs and Cats. In: Animal Pain. Kitchell, R.and Erickson, H. (eds). Amer. Physiol. Soc., Bethesda, 1983. pp. 207-216.8. Davis, L. Species Differences in Drug Disposition as Factors in Alleviation of Pain. In:Animal Pain. Kitchell, R. and Erickson, H. (eds). Ameri. Physiol. Soc. Bethesda, 1983. pp.161-168.9. Sawyer, D. Pain and Its Alleviation in Small Animals: Use of Analgesics for PostsurgicalPain. In: Minimizing Pain and Distress in Laboratory Animals. Proceedings of workshopsponsored by the National Institutes of Health, Office for Protection from Research Risks.Nashville, TN, Dec., 1992.10. Wixson S. Postoperative Pain Control and Chronic Pain Management in Small Animals. In:Minimizing Pain and Distress in Laboratory Animals. Proceedings of workshop sponsored bythe National Institutes for Health, Office for Protection from Research Risks. Nashville, TN,Dec., 1992.11. Flecknell, P. Post-operative Analgesia in Rabbits and Rodents. Lab Animal 20:34-37, 1991.
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A COMPENDIUM OF DRUGS USED FOR LABO
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SIGNS OF PAIN IN ANIMALSThe pain th
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Proposed Method to Quantify Pain, D
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needle is often used. To help preve
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GENERAL REQUIREMENTS FOR SURVIVAL S
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DETAILED CONSIDERATIONS FOR ANIMAL,
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SURGICAL SCRUB FOR THE SURGEONA. An
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RULES OF THUMB FOR ASSESSING THE NE
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Reptile:Sheep/Goat:Swine:meperidine
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ANALGESIA (8 OR MORE HOURS DURATION
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Reptiles:Sheep/Goat:Swine:ketaminea
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NEUROMUSCULAR BLOCKING/IMMOBILIZING
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fentanyl/droperidol, fentanyl/fluan
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A COMPENDIUM OF DRUGS USED FOR LABO
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Rabbit 3 0.1-0.2 mg/kg IV 21Rat 1 1
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ClassSourceNondepolarizing neuromus
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Rabbit 1 5-10 minutes 177Rabbit 2 8
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ClassSourceButyrophenone tranquiliz
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See commentsRabbit 50.5 mg/kg per r
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Rabbit 31.0 mg/kg SC, IM with acepr
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Bird 1-4 mg/kg IM 277Cat 1 2-4 mg/k
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Rat 12 hours 21 , 65 minutes (300 g
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Frog 30 mg/kg in dorsal lymph sac 2
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As long as gas is providedAntagonis
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Rabbit 11.0 mg/kg IM, IP 28 See com
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Cat 10.1-0.2 mg/kg IVCat 2 0.25-0.5
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Dosage frequencyDog 1, 25-10 minute
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Cat 4 5.0-10.0 µg/kg epidural 277D
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Dog 1 30 minutes 220Dog 3 2 hours 6
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Gerbil 1 20-30 minutes 177Gerbil 2
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Guinea Pig76, 17512-24 hoursHamster
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Dosage frequencyAs long as gas is s
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Rabbit 2 6-8 hours 269Rat 1 4 hours
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Bird 110-30 mg/kg IM with xylazine,
Page 69 and 70: Guinea Pig 12 44 mg/kg IM with acet
Page 71 and 72: Rabbit 14 Diazepam 0.2-0.5 mg/kg IV
Page 73 and 74: Sheep 12Sheep 131.5 mg/ml ketamine,
Page 75 and 76: Swine 1 30 minutes 221Swine 2 20 mi
Page 77 and 78: Dog 2142, 277Once a day for 5 daysF
Page 79 and 80: All species Topical on skin 15 minu
Page 81 and 82: Sheep 3 0.005 mg/kg IV 221Sheep 3 0
Page 83 and 84: Goat 1 Up to 200 mg/kg IM total dos
Page 85 and 86: Dog 2 0.7-1.0 mg/kg epidural 277Dog
Page 87 and 88: DogOften use flow rate of 15 ml/min
Page 89 and 90: MIVACURIUM (Mivacrom)Class Nondepol
Page 91 and 92: Guinea Pig 1 2-3 hours 5, 10 , 4 ho
Page 93 and 94: Primate 2 6 hours 76Rabbit 1 4-5 ho
Page 95 and 96: Dosage frequencyDog Every 24 hours
Page 97 and 98: Primate 1, 21, 2193-6 hoursRabbit 3
Page 99 and 100: Cat 3 6 hours 121Dog 1 4 hours 12 ,
Page 101 and 102: Cat 115-30 minutesCat 3 6 hours 72D
Page 103 and 104: Dog 1 8 hours 20Dog 1 up to 7 days
Page 105 and 106: Dog 1 0.11 mg/kg IV 178Dog 2See Met
Page 107 and 108: Dosage frequencyDog 15 minutes 50Co
Page 109 and 110: Cat 1, 2 Subsequent doses are ½ or
Page 111 and 112: Rat 1 30 mg/kg IV of 1.25% solution
Page 113 and 114: Swine 22.2 mg/kg IM with xylazine,
Page 115 and 116: ClassSourceAnestheticAldrich, Pfalt
Page 117 and 118: Swine 1 10 minutes 216 4 minutes 21
Page 119: CommentsCalf Will cause hyperglycem
Page 123 and 124: 29. Product insert for Ketaset (For
Page 125 and 126: 65. Silverman, J., Huhndorf, M., Ba
Page 127 and 128: 98. Malm, T., Bowald, S., Bylock, A
Page 129 and 130: 129. Vainio, O. and Ofala, M. Medet
Page 131 and 132: 172. Whelan, G. CompMed e-mail disc
Page 133 and 134: 211. J. Silverman, Clinical experie
Page 135 and 136: 250. Cooper, D. CompMed e-mail disc
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