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A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

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Rabbit 42.0 mg/kg Intranasal 86 Dilute with saline to 0.4 ml/kgRat 1 2 mg/kg IV 37Rat 2 4 mg/kg IM, IP 37Rat 3See KetamineReptile 1Red-eared slider turtle 1.5 mg/kg IM for musclerelaxation 280Reptile 2Snapping and Red-eared turtles 1.5 mg/kg IM withketamine 20-40 mg/kg IM. Sedation and anesthesia 280Reptile 30.5 mg/kg with oxymorphone (0.1 mg/kg) IM andglycopyrrolate (0.01 mg/kg) 0.4-1.3 mg/kg IV 221Sheep 0.4-1.3 mg/kg IV 221Swine 1 100-500µg/kg IM 3 IV 221Swine 2 100 µg/kg IM 128Swine 3 Thiopental (30 mg/kg IV) followed by midazolam (0.90mg/kg IV), then continuous infusion of 0.90 mg/kg/hr andfentanyl (0.25 mg/kg IV), then continuous infusion of0.025 mg/kg/hr 137Swine 4Piglet Ketamine 20 mg/kg IM then midazolam 1.0 mg/kgIM 88Swine 5Adult Ketamine 33 mg/kg IM, then midazolam 0.5 mg/kgIM 221Swine 6 Piglet 0.2 mg/kg intranasal for sedation 271Swine 7 Piglet o.4 mg/kg IV for sedation 271Dosage frequencyCat 2 Less than 2 hours 220Cattle 15-30 minutes 221Primate 1 30 minutes 282Rabbit 4 25 minutes 86Sheep 15-30 minutes 221Swine 1 20 minutes 221Swine 3 2 hours 137Swine 5 45 minutes 221AntagonistFlumazenil (q.v.) 22CommentsAllUse carefully with barbiturates or CNS depressants due torespiratory depression 72Dog 2 Good for aged or debilitated animals 70Rabbit 1-3See medetomidineRabbit 4 Dilates ear vessels 86Reptile 1 Not good in snapping turtles or painted turtles 280Swine May reduce blood pressure 258

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