A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

Dog 2142, 277Once a day for 5 daysFerret 24 hours 269Primate 2 Twice a day 208Primate 3 2-4 times a day 208Rabbit 1 12-24 hours 269Rabbit 2 24 hours 277Rat 1 24 hours 162Rat 2 24 hours 277Reptile 24-48 hours 277Swine 1 Single dose 238Swine 2 8-12 hours 240CommentsAllcyclooxygenase inhibitor. Use with caution in animalswith impaired renal, cardiovascular, hepatic or bleedingdisorder.Dog 1 If necessary, can supplement with oxymorphone 0.05-0.1mg/kg IM, IV or buprenorphine 0.01 mg/kg IM.Dog 2Dog 3Rat 1 Not effective PO 209Rat 34-5% vomiting incidenceBetter than oxymorphone or butorphanol for generalpostoperative pain 190One report of ulcerative, hemorrhagic gastroenteritisinvolving entire gut after two days of treatment. 236KETOROLAC (Toradol)Class Pyrrolo-pyrrole nonsteroidal anti-inflammatorySource Roche, Mylan, Fort DodgeDog 1 0.5 mg/kg IM 207Dog 2 30 mg IM if less than 17 kg. 60 mg IM if greater than 17kg 220Mouse 0.7-10 mg/kg PO 217Primate 1 Baboon 1.0 mg/kg (IM?) at time of procedure, then 0.75mg/kg every 6 hours 208Primate 2219, 269Macaque 15-30 mg/animal IMSwine 1.0 mg/kg IV 229 IM 240Dosage frequencyDog 1 Twice a day 207Dog 2 Every 6 hours 220Swine Four times a day 229CommentsAllCan inhibit platelet function.