A COMPENDIUM OF DRUGS USED FOR LABORATORY ANIMAL ...

Cat 3 6 hours 121Dog 1 4 hours 12 , 2-4 hours 277Ferret 4 hours 76Gerbil 2-4 hours 175Goat 3-4Guinea Pig 1 2-4 hours 175Hamster 2-4 hours 175Mouse 1 3-4 hours 175Primate 3-4 hours 1, 37, 277 < 1 hour 32Rabbit 1 & 2 1 hour 11 , 2-4 hours 175Sheep 2 hours 277Swine 4 hours 3, 37 IV 277AntagonistNaloxone (q.v.)CommentsAllRotate injection sites due to possible sclerosisCat 1 Weak analgesia 9Cat 1Minimal cardiovascular effects. Mild respiratorydepressant.Cat 2 Excitatory effects at this level. 9 Visceral, not somaticanalgesia. 20 Can cause dysphoria 72Dog 1, 3 For fractures, trauma, spinal disorders 72Dog 1, 3Minimal cardiovascular effects. Mild respiratorydepressant.PENTOBARBITAL (Nembutal)Class Barbiturate anesthetic, euthanasia agent. Controlled substance.Source Abbott, Fort Dodge, genericAmphibian 60 mg/kg in dorsal lymph sac 148Calf 15-30 mg/kg IV. Anesthesia 72Cat 1 20-28 mg/kg IV 6Cat 2 2-4 mg/kg IV. Sedative 72Cat 3 2-4 mg/kg PO. Sedative 72Cattle 2.0 mg/kg IV. Sedation. (30-60 min) 136Dog 1 20-28 mg/kg IV 6Dog 2 2.-4 mg/kg IV, PO. Sedative 72EuthanasiaMost species, as adults 150 mg/kg IV (preferred), IPFerret 1 30-36 mg/kg IP 116 , IV 148Ferret 2Not recommendedGerbil 60-100 mg/kg IP. 2, 37 See comments. Maximum 60 mg 148Goat 1 30 mg/kg IV. 37 Anesthesia.Goat 2 1.0-2.0 mg/kg IV for sedation 221Guinea Pig 1 35-40 mg/kg IP. 2 See comments.