Download Update 11 - Update in Anaesthesia - WFSA
Download Update 11 - Update in Anaesthesia - WFSA
Download Update 11 - Update in Anaesthesia - WFSA
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<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong> <strong>11</strong>PRACTICAL APPLICATIONS OF PULSE OXIMETRYDr E Hill, Dr MD Stoneham, Nuffield Department of Anaesthetics, Oxford Radcliffe NHS HospitalsHead<strong>in</strong>gton , Oxford OX3 9DU, Email: mark@stoneham1.freeserve.co.ukINTRODUCTIONPulse oximetry is a useful method of monitor<strong>in</strong>g patients <strong>in</strong>many circumstances,and <strong>in</strong> the face of limited resources,the pulse oximeter may represent a wise choice of monitor,as with tra<strong>in</strong><strong>in</strong>g it allows for the assessment of severaldifferent patient parameters.Pulse oximeters are now a standard part of perioperativemonitor<strong>in</strong>g which give the operator a non-<strong>in</strong>vasive<strong>in</strong>dication of the patient’s cardio-respiratory status. Hav<strong>in</strong>gbeen successfully used <strong>in</strong> <strong>in</strong>tensive care, the recovery roomand dur<strong>in</strong>g anaesthesia, they have been <strong>in</strong>troduced <strong>in</strong> otherareas of medic<strong>in</strong>e such as general wards apparently withoutstaff undergo<strong>in</strong>g adequate tra<strong>in</strong><strong>in</strong>g <strong>in</strong> their use (1) . Thetechnique of pulse oximetry does have pitfalls andlimitations and it is possible that patient safety may becompromised with untra<strong>in</strong>ed staff. This article is therefore<strong>in</strong>tended for the ‘occasional’ user of pulse oximetry.Pulse oximeters measure the arterial oxygen saturation ofhaemoglob<strong>in</strong>. The technology <strong>in</strong>volved (2) is complicatedbut there are two basic physical pr<strong>in</strong>ciples. First, theabsorption of light at two different wavelengths byhaemoglob<strong>in</strong> differs depend<strong>in</strong>g on the degree ofoxygenation of haemoglob<strong>in</strong>. Second, the light signalfollow<strong>in</strong>g transmission through the tissues has a pulsatilecomponent, result<strong>in</strong>g from the chang<strong>in</strong>g volume of arterialblood with each pulse beat. This can be dist<strong>in</strong>guished bythe microprocessor from the non-pulsatile componentresult<strong>in</strong>g from venous, capillary and tissue light absorption.The function of a pulse oximeter is affected by manyvariables, <strong>in</strong>clud<strong>in</strong>g: ambient light; shiver<strong>in</strong>g; abnormalhaemoglob<strong>in</strong>s; pulse rate and rhythm; vasoconstriction andcardiac function. A pulse oximeter gives no <strong>in</strong>dication of apatient’s ventilation, only of their oxygenation, and thuscan give a false sense of security if supplemental oxygen isbe<strong>in</strong>g given. In addition, there may be a delay betweenthe occurrence of a potentially hypoxic event such asrespiratory obstruction and a pulse oximeter detect<strong>in</strong>g lowoxygen saturation. However, oximetry is a useful non<strong>in</strong>vasivemonitor of a patient’s cardio-respiratory system,which has undoubtedly improved patient safety <strong>in</strong> manycircumstances.What does a pulse oximeter measure?1. The oxygen saturation of haemoglob<strong>in</strong> <strong>in</strong> arterialblood - which is a measure of the average amountof oxygen bound to each haemoglob<strong>in</strong> molecule.The percentage saturation is given as a digitalreadout together with an audible signal vary<strong>in</strong>g <strong>in</strong>pitch depend<strong>in</strong>g on the oxygen saturation.2. The pulse rate - <strong>in</strong> beats per m<strong>in</strong>ute, averaged over5 to 20 seconds.A pulse oximeter gives no <strong>in</strong>formation on any of theseother variables:The oxygen content of the bloodThe amount of oxygen dissolved <strong>in</strong> the bloodThe respiratory rate or tidal volume i.e. ventilation The cardiac output or blood pressureSystolic blood pressure can be estimated by not<strong>in</strong>g thepressure at which the plethysmograph trace reappearsdur<strong>in</strong>g deflation of a proximal non-<strong>in</strong>vasive blood pressurecuff.Pr<strong>in</strong>ciples of modern pulse oximetryOxygen is carried <strong>in</strong> the bloodstream ma<strong>in</strong>ly bound tohaemoglob<strong>in</strong>. One molecule of haemoglob<strong>in</strong> can carry upto four molecules of oxygen, which is then 100% saturatedwith oxygen. The average percentage saturation of apopulation of haemoglob<strong>in</strong> molecules <strong>in</strong> a blood sample isthe oxygen saturation of the blood. In addition, a verysmall quantity of oxygen is carried dissolved <strong>in</strong> the blood,which can become important if the haemoglob<strong>in</strong> levels areextremely low. The latter, however, is not measured bypulse oximetry.The relationship between the arterial partial pressure ofoxygen (PaO 2 ) and the oxygen saturation is described bythe haemoglob<strong>in</strong>-oxygen dissociation curve (see figure 1).The sigmoid shape of this curve facilitates unload<strong>in</strong>g ofoxygen <strong>in</strong> the peripheral tissues where the PaO 2 is lowand oxygen is required for respiration. The curve may beshifted to the left or right by various patient characteristicse.g. recent blood transfusion, pyrexia.