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Download Update 11 - Update in Anaesthesia - WFSA

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<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong> 87Fluids: 5 % dextrose <strong>in</strong> 0.45% sal<strong>in</strong>e; 1000mls each8hrsAnalgesia: Morph<strong>in</strong>e <strong>in</strong>fusion 20mg of morph<strong>in</strong>e <strong>in</strong>200mls of sal<strong>in</strong>e @ 10-15mls/hr titrated to effectHow would you anaesthetise a 50 year old previouslyhealthy patient scheduled for elective laparotomy andbowel resection?Dr Eddy Rahardjo, Dr.Sutomo Hospital, AirlanggaUniversity, School of Medic<strong>in</strong>e, Surabaya , IndonesiaPatients scheduled for bowel resection <strong>in</strong>variably have somedegree of bowel obstruction and malnutrition. Causes<strong>in</strong>clude malignancy, <strong>in</strong>flammatory bowel disease or morerarely cases of amoebiasis or extra-lumen abscessconstrict<strong>in</strong>g the bowel.Preoperative evaluation <strong>in</strong>cludes physical exam<strong>in</strong>ation,vital signs evaluation and laboratory evaluation of Hb, Hct,album<strong>in</strong>, creat<strong>in</strong><strong>in</strong>e, K + , Na + and blood glucose wheneverposssible. A chest X-ray will provide important data forthe lung conditions, possible lung metastases and heartconfiguration. ECG record<strong>in</strong>g is useful <strong>in</strong> identify<strong>in</strong>garrhythmias, coronary ischemia and hypertrophy.Premedication is determ<strong>in</strong>ed by the patient’spsychological state as assessed at the preoperative visit.A dose of midazolam 2.5 - 5mg i.m. will help relax thepatient; promethaz<strong>in</strong>e 1mg/kg i.m. or diazepam 0.2mg/kgi.m. are alternatives. This sedation applies for both generalor regional anaesthesia.When ether anaesthesia is planned, atrop<strong>in</strong>e 0.25mg i.mis given preoperatively followed by 0.25mg i.v. on<strong>in</strong>duction to prevent hypersecretion of the salivary andbronchial glands. Opioid analgesia should be providedwhen the plan <strong>in</strong>cludes halothane which has a low analgesicproperty (e.g. pethid<strong>in</strong>e 1mg/kg or morph<strong>in</strong>e 0.1 mg/kg).<strong>Anaesthesia</strong>: Some surgeons are capable of perform<strong>in</strong>gbowel resection very quickly. With such a surgeon epiduralanesthesia can sometimes be used for lower abdom<strong>in</strong>aloperations. A cont<strong>in</strong>uous lumbar epidural with the catheter<strong>in</strong>serted at the lumbar 2-3 <strong>in</strong>tervertebral space usuallyworks well. Lignoca<strong>in</strong>e 1.5% to 2.0% with 1:100,000adrenal<strong>in</strong>e is used to produce anaesthesia up to the sensorylevel of thoracic segment 4-6th. However regionalanaesthesia is not safer for this type of surgery and generalanaesthesia is usually preferred.Induction is usually with thiopentone or ketam<strong>in</strong>e andsuxamethonium followed by tracheal <strong>in</strong>tubation. This isfollowed by an <strong>in</strong>halational agent (halothane or ether)adm<strong>in</strong>istered with a non-depolaris<strong>in</strong>g muscle relaxant suchas pancuronium and controlled ventilation. Although deepether may be used with spontaneous or assisted ventilation(stage III plane 2 or 3), light ether anaesthesia (stage II orI) with pancuronium is preferred because the patient willrecover very quickly.Basic vital sign monitor<strong>in</strong>g <strong>in</strong>cludes blood pressure,pulse rate, temperature (usually rectal). A precordialstethoscope and a f<strong>in</strong>ger on the pulse is compulsory.Ventilation is usually manual, but when a simple ventilatoris used chest movement is observed cont<strong>in</strong>uously.Intravenous fluids: Preoperative hydration is 1000 mlof R<strong>in</strong>ger dextrose or R<strong>in</strong>ger’s lactate start<strong>in</strong>g before bowelpreparation and cont<strong>in</strong>ued up to the time of <strong>in</strong>duction.Dur<strong>in</strong>g surgery R<strong>in</strong>ger’s lactate or NaCl 0.9% is given at10ml/kg/hour via a 16G or 18G i.v.catheter placed <strong>in</strong> thearm.Blood loss <strong>in</strong> excess of 15% - 20% of estimated bloodvolume is replaced with blood transfusion. In my <strong>in</strong>stitutionwe try to delay transfusion until the postoperative periodif the circulation is stable. This allows the patient to compla<strong>in</strong>of any adverse effect from the transfusion. When transfusionis delayed, R<strong>in</strong>ger’s lactate 2-3 times the measured loss isgiven.Postoperatively: At the end of the procedure the patientis extubated and supplemental oxygen is given for 4-6hours postoperatively. The patient stays <strong>in</strong> the recoveryroom before be<strong>in</strong>g transferred to the ward. In manyhospitals there is a new trend of keep<strong>in</strong>g these patients <strong>in</strong>a high dependency care area so that the vital signs, fluidbalance and pa<strong>in</strong> management can be optimized.Postoperative <strong>in</strong>structions <strong>in</strong>clude pa<strong>in</strong> management,which is often oversimplified and not effective. Opioidsare frequently <strong>in</strong> short supply and this form of analgesiamay be impossible. Alternatively, i.v. NSAIDS are morereadily available but more expensive.R<strong>in</strong>ger’s lactate and dextrose 5% 40-50 ml/kg/day is givenpostoperatively tak<strong>in</strong>g <strong>in</strong>to account the high ambienttemperature <strong>in</strong> the ward. As soon as possible gradualoral alimentation is started and normal diet is resumedaround day 5 with most patients.Malnutrition occurs commonly <strong>in</strong> develop<strong>in</strong>g countries and<strong>in</strong>creases the risk of surgery considerably. Althoughparenteral nutrition has not been proved to be beneficial<strong>in</strong> these circumstances, we believe that giv<strong>in</strong>g some nutritionis better than none. The cost of dextrose 10% is exactlythe same as dextrose 5%, and some brands of am<strong>in</strong>o acid

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