86<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong>TECHNIQUES FROM AROUND THE WORLDThis is a new section of <strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong> <strong>in</strong> whichanaesthetists from different countries and different hospitalsexpla<strong>in</strong> how they anaesthetise for certa<strong>in</strong> types of surgery.Techniques vary widely from one facility to the next andwe hope to illustrate the different methods of anaesthesiawhich are used. In this edition, anaesthetists from SouthAfrica, India and Indonesia describe how they wouldanaesthetise a previously fit patient for bowel resection.<strong>Anaesthesia</strong> for a patient scheduled foran elective bowel resectionDr. Natalie Hendricks, Registrar, Department of<strong>Anaesthesia</strong>, Groote Schuur Hospital and University ofCape Town, Cape Town, R.S.A.The anaesthetic course would vary depend<strong>in</strong>g on the typeof surgery to be undertaken. This patient is scheduled fora simple laparotomy for a bowel resection, and not a majorprocedure such as an anterior- posterior resection.Preoperative preparation and <strong>in</strong>vestigations: Rout<strong>in</strong>epreoperative <strong>in</strong>vestigations <strong>in</strong>clude a f<strong>in</strong>ger prickhaemoglob<strong>in</strong>. Any further <strong>in</strong>vestigations would dependon the case scenario and the patient’s pre-morbid state.Premedication: Temazepam 10-20 mg depend<strong>in</strong>g onthe patients weight. DVT prophylaxis (for prolongedprocedures) with 5000 units of hepar<strong>in</strong> adm<strong>in</strong>isteredsubcutaneously.Pre-<strong>in</strong>duction: Venous access is established by plac<strong>in</strong>ga large bore <strong>in</strong>travenous catheter and the adm<strong>in</strong>istrationof modified R<strong>in</strong>gers lactateInduction: In the absence of any <strong>in</strong>dication for a rapidsequence <strong>in</strong>duction, anaesthesia would be <strong>in</strong>duced with3-4mg/kg of thiopentone and 0.1mg/kg of vecuronium.The patient is then manually ventilated via a facemask with50% oxygen <strong>in</strong> air and 1.5% halothane for 3 m<strong>in</strong>utes afterwhich an oral endotracheal tube is <strong>in</strong>serted. A rapidsequence <strong>in</strong>duction would be performed if there was anyrisk of reflux and aspiration.Ma<strong>in</strong>tenance: The patient is ventilated with an oxygen/air/ halothane mixture. If the patient had received halothanewith<strong>in</strong> the last 6 months, isoflurane would be used <strong>in</strong>stead.A circle system is used with a total flow of about 1 litre /m<strong>in</strong>ute.A nasogastric tube would be <strong>in</strong>serted. Intermittent bolusesof vecuronium to ma<strong>in</strong>ta<strong>in</strong> surgical relaxation. Analgesiawould be provided by 10-15mg of morph<strong>in</strong>e <strong>in</strong>travenously.Monitor<strong>in</strong>g: 3 lead ECG, non-<strong>in</strong>vasive blood pressureat 3 m<strong>in</strong>ute <strong>in</strong>tervals, pulse oximetry, capnography, ur<strong>in</strong>arycatheter and peripheral nerve stimulator. Nasopharyngealtemperature probe is used with prolonged surgery. An<strong>in</strong>ternal jugular CVP l<strong>in</strong>e would be placed if large volumesof fluid shifts were anticipated.Fluids: Modified R<strong>in</strong>gers lactate at approximately 6-8mls/kg/hr. Additional colloids and crystalloids adm<strong>in</strong>isteredas required to replace fluid and blood loss and for thirdspace losses.Other measures: Temperature is ma<strong>in</strong>ta<strong>in</strong>ed with forcedair warm<strong>in</strong>g blanket for a prolonged procedure. Dynamiccalf compressors are used to prevent DVT. Antibioticswould be given i.v. <strong>in</strong> theatre - benzyl penicill<strong>in</strong> 2 millionunits, gentamic<strong>in</strong> 6mg/kg and metronidazole 500mg.End of anaesthesia: Discont<strong>in</strong>uation of volatile agent.Reverse muscle relaxation with 0.4mg glycopyrrolate and2.5mg of neostigm<strong>in</strong>e. Extubate patient and transfer tothe recovery room, with 40% oxygen via a Venturifacemask.Recovery Room: Patient nursed <strong>in</strong> the recovery positionand given 40% oxygen by facemask. Monitor non-<strong>in</strong>vasiveblood pressure and pulse oximetry.Pa<strong>in</strong> Management: Further <strong>in</strong>travenous boluses ofmorph<strong>in</strong>e as required to ensure adequate analgesia beforetransfer to ward.Recovery discharge criteria for ward: Patient awake and able to cough Susta<strong>in</strong>ed head lift for 5 seconds Pa<strong>in</strong> free Haemodynamically stable No nausea or vomit<strong>in</strong>g Haemostasis as assessed via surgical dress<strong>in</strong>gPostoperative InstructionsMonitor<strong>in</strong>g: Rout<strong>in</strong>e postoperative monitor<strong>in</strong>g to <strong>in</strong>cludeheart rate, respiratory rate, blood pressure every 15m<strong>in</strong>utes for 2 hours and then 4 hourly if patient stable.
<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong> 87Fluids: 5 % dextrose <strong>in</strong> 0.45% sal<strong>in</strong>e; 1000mls each8hrsAnalgesia: Morph<strong>in</strong>e <strong>in</strong>fusion 20mg of morph<strong>in</strong>e <strong>in</strong>200mls of sal<strong>in</strong>e @ 10-15mls/hr titrated to effectHow would you anaesthetise a 50 year old previouslyhealthy patient scheduled for elective laparotomy andbowel resection?Dr Eddy Rahardjo, Dr.Sutomo Hospital, AirlanggaUniversity, School of Medic<strong>in</strong>e, Surabaya , IndonesiaPatients scheduled for bowel resection <strong>in</strong>variably have somedegree of bowel obstruction and malnutrition. Causes<strong>in</strong>clude malignancy, <strong>in</strong>flammatory bowel disease or morerarely cases of amoebiasis or extra-lumen abscessconstrict<strong>in</strong>g the bowel.Preoperative evaluation <strong>in</strong>cludes physical exam<strong>in</strong>ation,vital signs evaluation and laboratory evaluation of Hb, Hct,album<strong>in</strong>, creat<strong>in</strong><strong>in</strong>e, K + , Na + and blood glucose wheneverposssible. A chest X-ray will provide important data forthe lung conditions, possible lung metastases and heartconfiguration. ECG record<strong>in</strong>g is useful <strong>in</strong> identify<strong>in</strong>garrhythmias, coronary ischemia and hypertrophy.Premedication is determ<strong>in</strong>ed by the patient’spsychological state as assessed at the preoperative visit.A dose of midazolam 2.5 - 5mg i.m. will help relax thepatient; promethaz<strong>in</strong>e 1mg/kg i.m. or diazepam 0.2mg/kgi.m. are alternatives. This sedation applies for both generalor regional anaesthesia.When ether anaesthesia is planned, atrop<strong>in</strong>e 0.25mg i.mis given preoperatively followed by 0.25mg i.v. on<strong>in</strong>duction to prevent hypersecretion of the salivary andbronchial glands. Opioid analgesia should be providedwhen the plan <strong>in</strong>cludes halothane which has a low analgesicproperty (e.g. pethid<strong>in</strong>e 1mg/kg or morph<strong>in</strong>e 0.1 mg/kg).<strong>Anaesthesia</strong>: Some surgeons are capable of perform<strong>in</strong>gbowel resection very quickly. With such a surgeon epiduralanesthesia can sometimes be used for lower abdom<strong>in</strong>aloperations. A cont<strong>in</strong>uous lumbar epidural with the catheter<strong>in</strong>serted at the lumbar 2-3 <strong>in</strong>tervertebral space usuallyworks well. Lignoca<strong>in</strong>e 1.5% to 2.0% with 1:100,000adrenal<strong>in</strong>e is used to produce anaesthesia up to the sensorylevel of thoracic segment 4-6th. However regionalanaesthesia is not safer for this type of surgery and generalanaesthesia is usually preferred.Induction is usually with thiopentone or ketam<strong>in</strong>e andsuxamethonium followed by tracheal <strong>in</strong>tubation. This isfollowed by an <strong>in</strong>halational agent (halothane or ether)adm<strong>in</strong>istered with a non-depolaris<strong>in</strong>g muscle relaxant suchas pancuronium and controlled ventilation. Although deepether may be used with spontaneous or assisted ventilation(stage III plane 2 or 3), light ether anaesthesia (stage II orI) with pancuronium is preferred because the patient willrecover very quickly.Basic vital sign monitor<strong>in</strong>g <strong>in</strong>cludes blood pressure,pulse rate, temperature (usually rectal). A precordialstethoscope and a f<strong>in</strong>ger on the pulse is compulsory.Ventilation is usually manual, but when a simple ventilatoris used chest movement is observed cont<strong>in</strong>uously.Intravenous fluids: Preoperative hydration is 1000 mlof R<strong>in</strong>ger dextrose or R<strong>in</strong>ger’s lactate start<strong>in</strong>g before bowelpreparation and cont<strong>in</strong>ued up to the time of <strong>in</strong>duction.Dur<strong>in</strong>g surgery R<strong>in</strong>ger’s lactate or NaCl 0.9% is given at10ml/kg/hour via a 16G or 18G i.v.catheter placed <strong>in</strong> thearm.Blood loss <strong>in</strong> excess of 15% - 20% of estimated bloodvolume is replaced with blood transfusion. In my <strong>in</strong>stitutionwe try to delay transfusion until the postoperative periodif the circulation is stable. This allows the patient to compla<strong>in</strong>of any adverse effect from the transfusion. When transfusionis delayed, R<strong>in</strong>ger’s lactate 2-3 times the measured loss isgiven.Postoperatively: At the end of the procedure the patientis extubated and supplemental oxygen is given for 4-6hours postoperatively. The patient stays <strong>in</strong> the recoveryroom before be<strong>in</strong>g transferred to the ward. In manyhospitals there is a new trend of keep<strong>in</strong>g these patients <strong>in</strong>a high dependency care area so that the vital signs, fluidbalance and pa<strong>in</strong> management can be optimized.Postoperative <strong>in</strong>structions <strong>in</strong>clude pa<strong>in</strong> management,which is often oversimplified and not effective. Opioidsare frequently <strong>in</strong> short supply and this form of analgesiamay be impossible. Alternatively, i.v. NSAIDS are morereadily available but more expensive.R<strong>in</strong>ger’s lactate and dextrose 5% 40-50 ml/kg/day is givenpostoperatively tak<strong>in</strong>g <strong>in</strong>to account the high ambienttemperature <strong>in</strong> the ward. As soon as possible gradualoral alimentation is started and normal diet is resumedaround day 5 with most patients.Malnutrition occurs commonly <strong>in</strong> develop<strong>in</strong>g countries and<strong>in</strong>creases the risk of surgery considerably. Althoughparenteral nutrition has not been proved to be beneficial<strong>in</strong> these circumstances, we believe that giv<strong>in</strong>g some nutritionis better than none. The cost of dextrose 10% is exactlythe same as dextrose 5%, and some brands of am<strong>in</strong>o acid