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Download Update 11 - Update in Anaesthesia - WFSA

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72<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong>SummaryThe diabetic patient presents the anaesthetist with manychallenges. Careful attention to cl<strong>in</strong>ical signs and rapidaction to prevent even suspected hypoglycaemiaperoperatively should see them safely through their surgery.The goal is to keep th<strong>in</strong>gs as normal as possible. Regionaltechniques are often safer than general anaesthesia, butrequire the same vigilance.References:1. Hirsch IB, McGill JB, Cryer PE, White PF. Perioperativemanagement of surgical patients with diabetes mellitus.Anesthesiology 1991; 74: 346 - 59.2. Alberti KGMM. Diabetes and surgery. Anesthesiology1991; 74: 209 - <strong>11</strong>.Figure 5.Aims -Treatment of Diabetic Ketoacidosisrehydration (water and salt)lower blood sugarcorrection of potassium depletionStart an <strong>in</strong>travenous <strong>in</strong>fusion of 0.9 % sal<strong>in</strong>e as follows-1 litre over 30 m<strong>in</strong>utesthen 1 litre over 1 hourthen 1 litre over 2 hours.Cont<strong>in</strong>ue 2 - 4 hourly until the blood glucose is below 15 mmol / l,then change to 5% glucose, 1 litre 2 - 4 hrlyUp to 6 -8 litres of fluid may be required or more. Use cl<strong>in</strong>ical signs BP, heart rate, CVP, conscious level to judgethe amount.Give soluble <strong>in</strong>sul<strong>in</strong> (Actrapid) <strong>in</strong>tramuscularly (IM) as follows-- 20 units IM first dose then 6 units IM hourly- measure the blood glucose hourly- when the blood glucose is below 15 mmol/l, change to 6 units IM every 2 hours.Once the patient has recovered and is eat<strong>in</strong>g/dr<strong>in</strong>k<strong>in</strong>g, change to S/C <strong>in</strong>sul<strong>in</strong>.Potassium (K + ) supplementation will be required-There may be a high blood potassium <strong>in</strong>itially, but this will fall as the sugar level comes down.Measure the potassium hourly. Put 10 mmol K + <strong>in</strong> the first litre of sal<strong>in</strong>e then 10 - 40 mmol <strong>in</strong> subsequent litres offluid, depend<strong>in</strong>g on the plasma level (normal 3.5 - 5.0 mmol/l).If potassium measurements are unavailable then put 10 mmol KCl <strong>in</strong> each litre of fluid.Other measures- 100 % O 2. Blood gas estimation-if pH < 7.10, give 50 mmol of 8.4% bicarbonate. Usuallyacidosis will correct itself slowly as the sugar comes down. Emergency surgery can start once the rehydration andlower<strong>in</strong>g of blood sugar is underway.

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