66<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong>before and the tip will end posterior to the femur. This I would like to acknowledge the k<strong>in</strong>d assistance of Drmay help f<strong>in</strong>d the nerve, which tends to lie slightly beh<strong>in</strong>d Barry Nicholls for advice, particularly with regard to thethe femur at this level. (When us<strong>in</strong>g this more medial block techniques and Dr Krist<strong>in</strong>e Barnden for proof<strong>in</strong>jection po<strong>in</strong>t, it may help to place the free hand under read<strong>in</strong>g the manuscript.the buttock and palpate the ischial tuberosity. The needleReferencesis then aimed at a po<strong>in</strong>t estimated to be 1 - 2cm lateral to1. Selander D., Dhuner K.E. and Lundberg E. Peripheral nervethe ischial tuberosity.)<strong>in</strong>juries due to <strong>in</strong>jection needles used for regional anaesthesia.Perform<strong>in</strong>g a sciatic nerve block us<strong>in</strong>g a nerve Acta Anaesthesiologica Scand<strong>in</strong>avica 1977; 21: 182.stimulator A nerve stimulator may be used <strong>in</strong> 2. Khoo S.T. and Brown T.C.K. Femoral nerve block - theconjunction with any of the approaches to the sciatic anatomical basis for a s<strong>in</strong>gle <strong>in</strong>jection technique. <strong>Anaesthesia</strong>nerve that have been described above. The techniques and Intensive Care 1983; <strong>11</strong>: 40-2.for determ<strong>in</strong><strong>in</strong>g the po<strong>in</strong>t of <strong>in</strong>jection and locat<strong>in</strong>g the 3. W<strong>in</strong>nie A.P., Ramamurthy S. and Durrani Z. The <strong>in</strong>gu<strong>in</strong>alnerve are no different, except that one will look for paravascular technic of lumbar plexus anaesthesia. The “3-<strong>in</strong>-1muscle contraction. The best <strong>in</strong>dicator of proximity Block.” Anesthesia and Analgesia 1973; 52: 989-96.to the nerve is dorsiflexion of the foot at the ankle and 4. Dalens B., Tanguy A. and Vanneuville G. Sciatic nerve blocksone should aim to achieve this at a stimulat<strong>in</strong>g current <strong>in</strong> children: Comparison of the posterior, anterior and lateralapproaches <strong>in</strong> 180 paediatric patients. <strong>Anaesthesia</strong> and Analgesiaof 0.3 - 0.5 mA. However, when us<strong>in</strong>g the posterior1990; 70: 131-7.approaches, one may also see contraction of the5. Labat G. Regional <strong>Anaesthesia</strong>, Its Technique and Cl<strong>in</strong>ical“hamstr<strong>in</strong>g” muscles down the back of the thigh, whichApplication. Philadelphia. W.J. Saunders. 1924may be taken as a sign of proximity to the sciatic nerve.Hav<strong>in</strong>g achieved muscle contraction at the required Further read<strong>in</strong>g:stimulat<strong>in</strong>g current, <strong>in</strong>jection of local anaesthetic is 1. Macrae W.A. Lower Limb Blocks <strong>in</strong> Wildsmith J.A.W. andperformed <strong>in</strong> the usual manner.Armitage E.N. (eds)2. Bridenbaugh P.O. and Wedel D.J. The lower extremity - somaticAcknowledgementsblockade. In Cous<strong>in</strong>s M.J. and Bridenbaugh P.O. (eds) NeuralBlockade <strong>in</strong> Cl<strong>in</strong>ical <strong>Anaesthesia</strong> and Management of Pa<strong>in</strong> 3rded. pp 373 - 94 Lipp<strong>in</strong>cott-Raven 1998.CLINICAL MANAGEMENT OF DIABETES MELLITUS DURING3. Cov<strong>in</strong>o B.G. and Wildsmith J.A.W. Cl<strong>in</strong>ical pharmacology ofANAESTHESIA AND SURGERYlocal anaesthetic agents. In Cous<strong>in</strong>s M.J. and Bridenbaugh P.O.(eds) Neural Blockade <strong>in</strong> Cl<strong>in</strong>ical <strong>Anaesthesia</strong> and ManagementDr Gordon French FRCA, Northampton General Hospital, of Northampton, Pa<strong>in</strong> 3rd ed. pp UK. 97 - 128 Lipp<strong>in</strong>cott-Raven 1998.INTRODUCTIONDiabetes is a condition where the cells of the body cannotmetabolise sugar properly, due to a total or relative lackof <strong>in</strong>sul<strong>in</strong>. The body then breaks down its own fat, prote<strong>in</strong>sand glycogen to produce sugar, result<strong>in</strong>g <strong>in</strong> high sugar levels<strong>in</strong> the blood (hyperglycaemia) with excess by-productscalled ketones be<strong>in</strong>g produced by the liver.There are two ma<strong>in</strong> types of diabetes (table 1) whichclassically affect different age groups. In reality there is ahuge overlap between age groups.Diabetes causes disease <strong>in</strong> many organ systems, theseverity of which may be related to how long the diseasehas been present and how well it has been controlled.Damage to small blood vessels (diabetic microangiopathy)and nerves (neuropathy) throughout the body results <strong>in</strong>many pitfalls for the unwary anaesthetist. The follow<strong>in</strong>gguidel<strong>in</strong>es should help to identify these problems and copewith them.Preoperative assessment. The general preoperativeassessment has been reviewed <strong>in</strong> a previous article. <strong>Update</strong><strong>in</strong> <strong>Anaesthesia</strong> <strong>in</strong> 1997;7.Specific problems arise:Cardiovascular- diabetics are more prone tohypertension, ischaemic heart disease, cerebrovasculardisease, myocardial <strong>in</strong>farction which may be silent andcardiomyopathy. Damage to the nerves controll<strong>in</strong>g theheart and blood vessels (autonomic neuropathy) may result<strong>in</strong> sudden tachycardia, bradycardia or a tendency topostural hypotension. A history of shortness of breath,palpitations, ankle swell<strong>in</strong>g, tiredness and of course chestpa<strong>in</strong> should therefore be sought and a careful exam<strong>in</strong>ation
<strong>Update</strong> <strong>in</strong> <strong>Anaesthesia</strong> 67Table 1. Classification of diabetes mellitus *Insul<strong>in</strong> Dependent (Type I)Non Insul<strong>in</strong> Dependent (Type II)Age of onset Infancy to twenties Sixties onwards, occasionally youngerPathology Pancreas unable to produce Body unable to use <strong>in</strong>sul<strong>in</strong> properly<strong>in</strong>sul<strong>in</strong> (autoimmune disorder)Treatment Insul<strong>in</strong> Diet and oral hypoglycaemics.* Note. This is a general classification and there is considerable overlap. Obesity is a common cause of Type II- the pancreas cannotmake enough <strong>in</strong>sul<strong>in</strong> for the body size. Diet /oral hypoglycaemics may <strong>in</strong>itially be enough but eventually <strong>in</strong>sul<strong>in</strong> may be required.for heart failure (distended neck ve<strong>in</strong>s, ankle swell<strong>in</strong>g,tender swollen liver, crackles heard on listen<strong>in</strong>g to the chest)made. A preoperative ECG should be performed. Heartfailure is a very serious risk factor and must be improvedbefore surgery with diuretics. Table 2 describes how totest cl<strong>in</strong>ically for autonomic neuropathy.Renal - kidney damage may already be present, often<strong>in</strong>dicated by the presence of prote<strong>in</strong> (album<strong>in</strong>) <strong>in</strong> the ur<strong>in</strong>e.Ur<strong>in</strong>e <strong>in</strong>fections are common and should be treatedaggressively with antibiotics. The diabetic is at risk of acuterenal failure and retention postoperatively. Bloodelectrolyte measurement (if possible) may reveal a raisedurea and creat<strong>in</strong><strong>in</strong>e. If the potassium is high (> 5 mmol/l)then specific measures should be taken to lower it beforesurgery.Respiratory - diabetics, especially if obese and smokers,are particularly prone to chest <strong>in</strong>fections. Chestphysiotherapy pre and postoperatively are <strong>in</strong>dicated, withnebulised oxygen and regular bronchodilators (salbutamol2.5-5mg <strong>in</strong> 5ml sal<strong>in</strong>e) if wheeze is heard. A chest X-ray,blood gases and spirometry are the gold standard<strong>in</strong>vestigations, but careful repeated cl<strong>in</strong>ical assessment willusually reveal when a patient is as good as they are go<strong>in</strong>gto get. Non-emergency surgery should be delayed untilthis po<strong>in</strong>t.Airway - thicken<strong>in</strong>g of soft tissues occurs eg ligamentsaround jo<strong>in</strong>ts. If the neck is affected there may be difficultyextend<strong>in</strong>g the neck, mak<strong>in</strong>g <strong>in</strong>tubation difficult. To test ifthe patient is at risk, ask them to br<strong>in</strong>g their hands togetheras <strong>in</strong> pray<strong>in</strong>g. If they cannot have the f<strong>in</strong>gers of each handflat aga<strong>in</strong>st the other hand, then they probably have ligamentthicken<strong>in</strong>g of the f<strong>in</strong>ger jo<strong>in</strong>ts, and difficult <strong>in</strong>tubation shouldalso be anticipated.Gastro<strong>in</strong>test<strong>in</strong>al - the nerves to the gut wall and sph<strong>in</strong>cterscan be damaged. Delayed gastric empty<strong>in</strong>g and <strong>in</strong>creasedreflux of acid make them more prone to regurgitation andat risk of aspiration on <strong>in</strong>duction of anaesthesia. A historyshould be sought of heartburn and acid reflux when ly<strong>in</strong>gflat; if present they should have a rapid sequence <strong>in</strong>ductionwith cricoid pressure, even for elective procedures. Ifavailable, prescribe an H 2antagonist and metoclopramideas a premedication. Ranitid<strong>in</strong>e 150mg or cimetid<strong>in</strong>e 400mgplus metoclopramide 10mg orally 2 hours preoperativelyto reduce the volume of stomach acid.Table 2: Detect<strong>in</strong>g autonomic neuropathyTests for autonomicNormal response Abnormal responseneuropathySympathetic System Measure systolic blood Decrease < 10 mm Hg Decrease > 30 mm Hgpressure ly<strong>in</strong>g down thenstand<strong>in</strong>g.Parasympathetic Measure heart rate response Increase rate > 15 beats /m<strong>in</strong> Increase < 10 beats /m<strong>in</strong>systemto deep breath<strong>in</strong>gNote: if above detected, patient at risk of unstable BP, myocardial ischaemia, arrhythmias, gastric reflux and aspiration, <strong>in</strong>abilityto ma<strong>in</strong>ta<strong>in</strong> body temperature under anaesthesia.