SUNDAY, APRIL 22 Across Societies – Experimental Biology

BIOCHEMISTRY557. PROTEOLYTIC ENZYMES AND INHIBITORS(CHEMICAL BIOLOGY)PosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMA102 557.1 Candida albicans exhibits a pepstatinA-insensitive secreted aspartic protease as a virulence factor.W. Aoki, N. Kitahara, N. Miura, H. Morisaka, Y. Yamamoto, K.Kuroda and M. Ueda. Grad. Sch. of Agr., Kyoto Univ., JSPS,Kyoto and Kyoto Municipal Indust. Res. Inst.A103 557.2 Inhibition of PC1/3 and PC2 by2,5-dideoxystreptamine derivatives. M. Vivoli, T.R. Caulfield, K.Martínez-Mayorga, A.T. Johnson, G-S. Jiao and I. Lindberg.Univ. of Maryland Sch. of Med., Mayo Clin., Jacksonville, FL,Torrey Pines Inst. for Molec. Studies, Port St. Lucie, FL andPanthera Biopharma LLC, Aiea, HI.A104 557.3 Ceruloplasmin binds and inactivates matrixmetalloproteinase-2. M.W. Thompson. Jefferson Tech andCommunity Col., Louisville.558. REGULATION AND ALLOSTERISMPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMA105 558.1 Structural insights into regulation of vertebratehomolog N-acetylglutamate synthase/kinase from Maricaulismaris. D. Shi, Y. Li, J. Cabrera-Luque, Z. Jin, X. Yu, G. Zhao,N.M. Allewell and M. Tuchman. Children’s Natl. Med. Ctr.,Gannan Normal Univ., China, Argonne Natl. Lab. and Univ. ofMaryland College Park.A106 558.2 Allosteric regulation of protein kinase PKCζ bythe N-terminal C1 domain and small compounds to the PIFpocket.R.M. Biondi, J.O. Schulze, W. Fröhner, H. Zhang,N. Weber, J. Navratil, S. Amon, V. Hindie, S. Zeuzem, T.J.D.Jørgensen, P.M. Alzari, S. Neimanis, M. Engel and L.A.Lopez-Garcia. Univ. Clin. Frankfurt, Univ. of Saarland, Univ. ofSouthern Denmark and Pasteur Inst., Paris.A107 558.3 The effects of citrate on glyoxasomal malatedehydrogenase. J. Mays, J. Marion and E. Bell. Univ. ofRichmond and Virginia Commonwealth Univ.A108 558.4 Mutational evidence for a substrate activationsite in phosphoenolpyruvate carboxylase. S. Halaby and S.D.Grover. California State Univ., Los Angeles.A109 558.5 Probing the role of proline-288 in the regulationof Agrobacterium tumefaciens ADPglucose pyrophosphorylase.G. Bains, D. Guzman, J. Sanders, H. Karzai, S. Bor, A. Orryand C.R. Meyer. California State Univ., Fullerton and MolSoftLLC, San Diego.A110 558.6 Expression, purifi cation, and initialcharacterization of the diverse ADPglucose pyrophosphorylasefrom Thermodesulfovibrio yellowstonii. M. Berriman, T. Kieu,T. Cheever, A. Orry and C.R. Meyer. California State Univ.,Fullerton and MolSoft LLC, San Diego.A111 558.7 Evidence for specifi c roles of arginines 26 and38 in the allosteric regulation of ADP glucose pyrophosphorylasefrom Thermus thermophilus. J. Sanders, D. Doshi, F. Botero, T.Truc, A. Orry and C.R. Meyer. California State Univ., Fullertonand MolSoft LLC, San Diego.A112 558.8 The effects of leucine on regulation ofglutamate dehydrogenase by purine nucleotides. R. McMullanand E. Bell. Univ. of Richmond.A113 558.9 The role of methionine residues in activity andsubunit communication in malate dehydrogenase. F. Billueand E. Bell. Univ. of Richmond.A114 558.10 Understanding glycosaminoglycan-proteinspecifi city through computational approaches. U.R. Desai andP.D. Mosier. Virginia Commonwealth Univ.A115 558.11 Effect of an added spacer on the ‘doublelockdown’ inhibition of kinesin-1 by tail domains. D.D. Hackneyand Y.W. Yeo. Carnegie Mellon Univ.559. SMALL MOLECULE TOOLS FOR BIOLOGYPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMA116 559.1 Bovine serum albumin interactions with metallicnanoparticles. M.C. Demirdji, M.R. Shah, R.H. Ramon,L.K. Rowland, T.S. Sabir, M.A. Payne, C.C. Perry and D.S.Boskovic. La Sierra Univ., Azusa Pacifi c Univ. and Loma LindaUniv.560. STRUCTURAL ENZYMOLOGYPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMA117 560.1 Allosteric reversion of Haemophilus infl uenzaeβ-carbonic anhydrase by a proline shift variant. R.S. Rowlett,K.M. Hoffmann, H.R. Million-Perez, R. Merkhofer and H.E.Nicholson. Colgate Univ. and Gonzaga Univ., WA.A118 560.2 Molecular analysis of site-directed mutantsof phosphoethanolamine methyltransferase from the malariaparasite Plasmodium falciparum. T. Alpert, S.G. Lee and J.Jez. Washington Univ. in St. Louis.A119 560.3 The structure of a ternary complex of porcinesarcosine dehydrogenase with glycine and folic acid. J-J. Kim,W. Yong, I. Misra and Z. Fu. Med. Col. of Wisconsin.561. STRUCTURAL ENZYMOLOGY OF MEMBRANEPROTEINSPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMSUNDAYA120 561.1 Examining the role of lipoprotein-associatedphospholipase A2 in atherosclerosis. T.E. Gilpatrick, J.Tomczak and B.J. Bahnson. Univ. of Delaware.152