SUNDAY, APRIL 22 Across Societies – Experimental Biology

BIOCHEMISTRYA310 604.4 Pannexin 1 knockdown in metastatic melanomacells induces cell differentiation into a melanocytic phenotypedecreasing tumor size and metastasis in vivo. S. Penuela,L. Gyenis, A. Ablack, J. Churko, A. Berger, J. Lewis, D.Litchfield and D. Laird. Univ. of Western Ontario.A311 604.5 Identifi cation of the structural domains ofTrypanosoma brucei Tim17 that is required for its function. E.I.Weems and M. Chaudhuri. Meharry Med. Col.A312 604.6 Characterization of rOrf8/EscI of theenteropathogenic Escherichia coli as an inner rod protein. N.Sal-Man, W. Deng and B.B. Finlay. Univ. of British Columbia.605. VESICULAR TRAFFICKINGPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 12:25 PM-1:55 PMA313 605.1 S. cerevisiae Env7 encodes a novel vacuolarmembrane kinase involved in delivery or function at thevacuole and is an ortholog of human Ser/Thr kinase STK16.E. Gharakhanian, S. Manandhar, S. Cocca and F. Ricarte.California State Univ., Long Beach.A314 605.2 Determination of the intracellular, surface,and extracellular localization of Hsp70s under different stressconditions. R. Medina, M. Rashedan and N. Nikolaidis.California State Univ., Fullerton.A315 605.3 A fi brinogen-derived peptide induces clathrinandcaveolae-independent endocytosis in endothelial cells. D.Serrano, C. Garnacho and S. Muro. Univ. of Maryland CollegePark.A316 605.4 A novel mechanism of trancytosis of drugcarriers across gastrointestinal epithelial cells mediated byICAM-1. R. Ghaffarian, T. Bhowmick and S. Muro. Univ. ofMaryland College Park.A317 605.5 S. cerevisiae ENV9, ENV10 and ENV11 arenovel genes involved in lysosomal vacuole events and theirproducts localize to lipid droplets, ER, and nucleus, respectively.L.A.K. Remington, T. Hseuh and E. Gharakhanian. CaliforniaState Univ., Long Beach.A318 605.6 Characterization of the interaction betweensorting nexin 27 and β-catenin in kidney epithelial cells. B.Duchez, S.L. Milgram and M.P. Playford. NHLBI/NIH.A319 605.7 The Vibrio parahaemolyticus effector VopQinduces autophagosome accumulation in host cells. A.Sreelatha, T. Bennett, V. Starai and K. Orth. Univ. of TexasSouthwestern Med. Ctr.and Univ. of Georgia.A320 605.8 A model system to investigate antibody bipolarbridging mediated by gE-gI, a herpes virus Fc receptor. B.Ndjamen, A. Farley and P.J. Bjorkman. Caltech and MIT.606. GLYCOCONJUGATES IN PATHOGEN INVASIONAND VIRULENCEPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMA321 606.1 Nucleotide sugar transporters of Trypanosomabrucei: glycosylation and infectivity. L. Liu, Y-X. Xu, B.A.Burleigh, J.D. Bangs and C.B. Hirschberg. Boston Univ.Goldman Sch. of Dent. Med., Harvard Sch. of Publ. Hlth. andUniv. of Wisconsin-Madison.A322 606.2 Generation of an IgG monoclonal antibody toLacdiNac glycan epitopes from splenocytes of Schistosomamansoni- infected Swiss Webster mice. V.H. Bartlette, B.Mamphey, M. Mandalasi and K. Nyame. Univ. of MarylandEastern Shore.A323 606.3 Receptor determinants for the aviancoronavirus infectious bronchitis virus: roles of hosT cell lectinsand glycans. Y. Zhang and G. Whittaker. Cornell Univ.607. ROLE OF GLYCOCONJUGATES IN SIGNALINGAND DEVELOPMENTPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMSUNDAYA324 607.1 O-GlcNAc, a novel paradigm for regulatingstress-induced signal transduction pathways. S. Sengupta,T. Boronina, V. Paruchuri, R. Cole and N.E. Zachara. JohnsHopkins Univ. Sch. of Med.A325 607.2 Extension of poly-N-acetyllactosamine chain inhuman cancer cell lines is under src regulation. K. Hwa, H-C.Liu and T-Y. Chou. Natl. Taipei Univ. of Technol. and TaipeiVeterans Gen. Hosp.A326 607.3 Thrombospondin-1 signaling via CD47regulates T lymphocyte glycosaminoglycan biosynthesis. S.Kaur, S.A. Kuznetsova, M.L. Pendrak, J.M. Sipes and D.D.Roberts. NCI/NIH.A327 607.4 Global increases in O-GlcNAc levels lead todifferentiation of myoblasts. K. Vaidyanathan and L. Wells.Univ. of Georgia.A328 607.5 NogoB receptor is essential for extraembryonicvascular development and protein glycosylation. E.J. Park andW.C. Sessa. Sch. of Med., Yale Univ.A329 607.6 The role of N-linked glycosylation duringDrosophila embryonic development. A. McCague and E.Selva. Univ. of Delaware.A330 607.7 Nonenzymatic and enzymatic functions of theSkp1 αgalactosyltransferase in Dictyostelium oxygen-sensing.C.M. Schafer, D. Zhang and C.M. West. Univ. of OklahomaHlth. Sci. Ctr.162