SUNDAY, APRIL 22 Across Societies – Experimental Biology

BIOCHEMISTRY613. PROTEIN-SMALL MOLECULE INTERACTIONSPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 12:25 PM-1:55 PMA349 613.1 The role of histidines in neurosteroid binding ofNMDA NR2B and D subunits. S. Rhoads, S. Biello, L. Zemcikand L. Gentile. Univ. of Richmond.A350 613.2 Alterations in the activity of the yeastperoxiredoxin Tsa1 upon modifi cation by alkylating agents. H.A.Brown, S.L. Justice, F.J. Garcia, K.S. Carroll, K.A. Moranoand J.D. West. Col. of Wooster, OH, Scripps Res. Inst. Floridaand Univ. of Texas Med. Sch. at Houston.A351 613.3 Disruption of the HIF-1α/p300 interactionas a means of inhibiting angiogenesis. K.M. Reece, E.D.Richardson, S.T. Pisle, A.J. Holly, T.J. Campbell and W.D.Figg. NCI/NIH and SAIC, NCI-Frederick.A352 613.4 Understanding the regulation of AMPA andNMDA iGluRs through the binding of sulfated neurosteroids.E.I. Bartle, D. Fanelli, R. Roark, A. Young and L. Gentile.Univ. of Richmond.A353 613.5 Study of a potent small-moleculebenzosuberene anti-cancer agent. A.K. Charlton-Sevcik,T.E. Strecker, S.O. Odutola, J.K. Tidmore, R.P. Tanpure,C.S. George, M. Sriram, D.J. Chaplin, K.G. Pinney and M.L.Trawick. Baylor Univ. and Oxigene Inc., San Francisco.A354 613.6 A fl uorescent glutathione analog for monitoringinteractions of GST fusion proteins. H.C. Huff, C.R. Gainesand B.D. Caldwell. Missouri Western State Univ. and BoysLatin Sch. of Maryland, Baltimore.614. CASPASESPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 12:25 PM-1:55 PMA355 614.1 Optimization of expression of Schizophyllumcommune metacaspase gene scp1 via codon-optimization,prodomain removal, and autoinduction. A. Major and K.M.Fox. Union Col., NY.A356 614.2 CASP-8 D302H gene polymorphism andsusceptibility to primary brain tumors. S. Pence, C. Cacina, S.Turan, F. Genc, A. Kafadar, M.Y. Kaynar and I. Yaylim Eraltan.Istanbul Univ. Inst. for Exptl. Med. Res. and Cerrahpasa Med.Fac., Turkey.615. SIGNALING IN DISEASE AND THERAPYPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 12:25 PM-1:55 PMA357 615.1 Physiologic cardiac hypertrophy and cardiacdilation: a comparative study using ZmRacD transgenicmouse model. M.T. Elnakish, M.D.H. Hassona, M.A. Alhaj,L. Moldovan, M. Khan and H.H. Hassanain. The Ohio StateUniv.A358 615.2 Cardiotonic steriods induce stress signalingin preeclamsia: a translational approach with in vivo, in vitro,and patient studies. M.N. Uddin, D. Horvat, S.R. Allen, R.O.Jones, D.C. Zawieja and T.J. Kuehl. Scott & White HealthcareandTexas A&M Hlth. Sci. Ctr. Col. of Med., Temple.A359 615.3 A sphingosine derivative recruits regulatoryT cells to the kidney by nuclear translocation of NFκB andupregulation of CCL5. E. Ly, K-C. Yong, Y-H.H. Lien and L-W.Lai. Univ. of Arizona.A360 615.4 Antiproliferative factor regulates connectivetissue growth factor (CTGF/CCN2) expression in T24 bladdercarcinoma cells. S.L. Planey, C.A. Matika, J.A. Arnott and M.Wasilewski. The Commonwealth Med. Col., PA.A361 615.5 Effects of iron defi ciency on the activationof glial cells against an antigenic challenge. I. Contreras-Garcia, J.A. Estrada-Guadarrama and F.B. Pliego-Rivero.Autonomous Univ. of State of Mexico.A362 615.6 Structure and function of E3 ubiquitin ligasemindbomb RING domain. R.D. Wardlow II, S.H. Choi, B.McMillan and S.C. Blacklow. Univ. of Maryland BaltimoreCounty and Dana-Farber Cancer Inst.A363 615.7 The effects of Gαz signaling on pancreaticβ-cell function and mass. M.E. Kimple, J.B. Moss, H.K. Brar,T.C. Rosa, C.B. Newgard and P.J. Casey. Univ. of Wisconsin-Madison and Duke Univ. Med. Ctr.A364 615.8 Stress-activated cellular senescence as amechanism of melanocytes degeneration in vitiligo. B. Bellei,A. Pitisci, M. Ottaviani, M. Ludovici, C. Cota, L. Fabiola, M.L.Dell’Anna and M. Picardo. IFO San Gallicano Dermatol. Inst.,Rome.A365 615.9 Modulation of microRNA miR-29c in a novelcross-talk between mTOR complex 1 and angiotensin II type2 receptor AT2R: an adaptive mechanism in over-nutrition. L.Pulakat, R. Gul, S. Arnold, V. DeMarco and J.R. Sowers.Univ. of Missouri-Columbia.A366 615.10 HSP90 is a novel target of thrombospondin-1to regulate colon cancer development. J. Ling, L. Gutierrez,Z. Lopez-Dee, S. Pan, V. Kalter, C. Cottell and D. Nye. TheCommonwealth Med. Col., Wilkes Univ. and Univ. of California,Riverside.616. MAXIMIZING TEACHING EFFECTIVENESSPosterSUN. 7:30 AM—SAN DIEGO CONVENTION CENTER, EXHIBITHALLS A-DPresentation time: 1:05 PM-2:35 PMSUNDAYA367 616.1 The effectiveness of images in the developmentof conceptual understanding in undergraduate biochemistryclasses: what do we know? R. Milner. Univ. of Alberta.A368 616.2 Probing and improving students’ understandingof protein alpha helix structure using targeted assessment andclassroom interventions. J. Loertscher, V. Minderhout, J.E.Lewis and S.M. Villafane. Seattle Univ. and Univ. of SouthFlorida.A369 616.3 Monkeys, beach balls, and Twinkies ® : usinganalogies to teach enzyme kinetics. E.A. First. LSU Hlth. Sci.Ctr., Shreveport.A370 616.4 Design of purifi cation and analysis protocolsfor ribofl avin binding protein in an undergraduate biochemistrylaboratory. T. Arnold Murray. Capital Univ., OH.164