2005/2006 - Registrar - McMaster University

1 60 ,BIOLOGYPrer.equisite: BIOCHEM 3P03 and registration in an H6nours Bi6ch~mistrySpecialization. Permission of the department is required. Application forpermission must be received by March 1 st of the academic year prior toregistration. Students are I?xpected to have a C.A. of at least 9.5. Forfurther information,please refer to .www.fhs.mcmaster.ca/biochem/ ''Undergraduate.htm.,Antirequisite: BIOCHEM 4B06, 48B6, 4G03, 4L03, 4LL3, 4P03,CHEM ENG 4LL3, Enrolment is limited. See the heading Limited Enrolment Courses in theFaculty of Science section of the Caleridar. 'BIOCHEM 4H03 BIOTECHNOLOGY AND DRUG DISCOVERYSeleeted topics on genomics, piOteomics and bioinfyrmatics illustratingthe modern, application of mole9ular biologyand biochemistry to pharma~ceutical andbther research; ,Three lectures; first term "Prerequisite: One of BIOCHEM 3BB3; 3BT3, 3D03; orBIOCHEM3G03 andregistration in a Chemical Engineering program; or HTH SCI 2E03, Antirequisite: BIOCHEM 4DD3 ,,BIOCHEM 4J03 BIOCHEMICAL IMMUNOLOGYThis advanced course applies small-group-based learning to immunologicalproblems. Topics concern development of .immunoassays, r~sistanceto infection and immunity in health and disease. \One session (two hours), one tutorial; one termPrerequisite:BIOLOGY 3X03 or HTH SCI 3103; and one of BIOCHEM 3B03,3BT3, 3D03, 3G03, BIOLOGY 3H03Cross-list: HTH SC14J03, 'MOL BIOL 4J03 . ,"This, course is administered by' the Bachelor of Health, Sciences (Hon- ,ours) Program.'BIOCHEM 4K03 STRUCTURE AND FUNCTION OFMEMBRANES AND MACROMOLECULESMoiecular components of biological membranes and their interactions. Tral'ls~port and other membrane-mediated processes. Membrane-bound receptorsand signal transduction. Advanced aspects of macromolecular structure.Three lectures; second termPrerequisite: One Of ' BlOCH EM 3BB3, 3BT3,,3D03, 3G03; or BIOCHEM2BB3 and registration in Honours Chemistry (Biological' Specialization);, or HTH SCI 2E03, , ' ,Antirequisite: BIOCHEM 4103, 4M03BIOCHEM 4L03 ADVANCED BIOCHEMISTRY LABORATORYFundamental principles of experimental bioch~ri1istry with emphasis onmodern methods in enzymology and molecular biology.Two labs {four hours); first term 'Prerequisite: BIOCHEM 3L03, 3BT3;or BIOCHEM 3L03 and one of BIOCHEM2B03, 3B03, BIOLOGY 3H03; and one of BIOCHEM 3BB30r 3D03Antirequisite: BIOCHEM 4B06, 4BB6, 4F09, 4G03, 4LL3, CHEM ENG 4LL3,MOL BIOL 4R09'Not open to students registered in Honours Biochemistry (BiotechnoF..ogy and GenetIc 'Engineering Specialization).'BIOCHEM 4LL3 BIOTECHNOLOGY AND GENETICENGiNEERING LABORATORYRecombinant DNA technology including cloning, directed mutagenesis,DNA sequenCing and expression of cloned genes. Reaction kinetics andreactor design for enzyme and fermentation reactions. Advanced sepa- 'ration methods for bioprocessing operations.'Two labs (four hours); second, term 'Prerequisite: BIOCHEM 4H03 and registration in Honpurs Bioch(3mistry{Biotechnology and Genetic Engineering Specialization); or BIOCHEM 3G03and registration in a Chemical Engineering program 'Antirequisite: BIOt.HEM4BB6, 4F09, 4G03, 4L03Cross-list: CHEM ENG 4LL3, BIOCHEM 4P03 RESEARCH PROJECT IN BIOCHEMISTRYAND MOLECULAR BIOLOGYA project supervised by a member or associate member of the Depart- ,ment of Biochemistry and Biomedical, Scienc,es. Assessment is basedon ,laboratory, work and a final report.May be taken first or second termPrerequisite: BIOCHEM 3P03 or BIOLOGY 3V03; and one of BIOCHEM3B03, 3BT3, 3D03, BIOLOGY 3H03; and registration inan Honours BiochemistrySpecialization, Honours Molecular Biology or Honours Physics(Biophysics Specialization). Permission of the Department is required.Application for permission must be received by March 1st of the academicyear prior to registration. Students are expected to have a C.A. ,of at least7;0. F.orfurther information, please refer to www.fhs.mcmaster.ca/biochem/UndergradLiate:htm. ' ,fAntirequisite: BIOCHEM4B06, 4F09, HTH SCI 3H03, 4A09, 4B06, MOLBIOL4R09 ' ,Enrolment is limited. See the heading Limited Enrolment Courses in theFaculty of Sciem:;esection of the Calendar.BIOCHEM 4Q03 ' BIOCHEMICAL PHARMACOLOGYThe pharm?cological and bioohemicalbasis of drug absorption, distribution,metabolism,biotrarisfor'1lation, toxicity and susceptibility. Chemicalcarcinogenesis and mechanism of action and cellular resistance to ariti~'bacterial and anticancer drugs.Three lectures; first termPrerequisite: One of BIOCHEM 38B3, 38T3, 3D03;or BiOCHEM 2EE3 and3G03; or HTH SCI 2E03 'BIOCHEM 4Y03 . COIVIPUTATIONAL BIOLOGY ,Theory and computational algorithms used in 'bioinformatics: sequencealignments; database searches; phylogenetic methods; hidden Markovmodels; 'neural networks; computational genomics; database design; informationmanagement. .Three lectures; second term ,Prerequisite: One of BIOCHEM3Y03, BIOLOGY 3S03 or permission ofthe Department .' -PHYSICS 4S03 MOLECULAR BIOPHYSICSThermodynamics of protein folding, RNA and DNA structure.Macromolecular structures within the cell: microtubules, actin filaments,protein complexes, membranes, molecular motors. PhYSical techniquesfor studying, biomolecular structure and dynamics. ' .Three lectures; firstterm "Prerequisite: One of CHEM 2R03, MATLS 2803 or PHYSICS 2H04. PHYS-ICS 3S03 is recommended.''BIOLOGY,WEB ADDRESS:http://www.science.mcmaster.ca/biology/'life Sciences Building,' Room 118Ext. 23049-Faculty as of January 15, 2005Acting Chair. (UntiiJune 30,2005), Rama S. SinghChair (Effective July '1" 2005)Turlough M. Finan , 'Associate ChairsAndre Bedard/Graduate Studies (Until June 30, 2005)Patricia Ch0IJl{-Fraser/Undergraduate ,Studies'Elizabeth A WeretilnyklGraduate Studies (Effective July 1, 2005), Professors'Turlough M. Finan/B.Sc., M~Sc. (Galway), Ph.D.' (Guelph)G. Brian Golding/ B.Sc. (Dalhou$ie), Ph.D., (Alberta)/Senior Canada ResearchChair''Delsworth G. Harnish/(Pathology .and Mo.lecular Medicine) B.Sc., M.Sc.(Queen:s), Ph.D. (McMaster) ,John A. Hassell/ (Biochemistry and Biomedical Sciences, Pathology and,Molecular: Medicin~) B.Sc. (Brooklyn Coljege), Ph.D. (Connecticut)J.' Roger Jacobs/B.Sc. (Calgary), M.Sc., Ph.p. (Toronto)Jurek Kolasa/M.Sc., Ph.D. (Poznan) , 'Colin A. Nurse/B.E.Sc. (Western Ontario), Ph.D. (Harvard)Michael J. O'Donnell/B.Sc., Ph.D~ (Toronto)Andrew J. Rainbow/B.Sc. (Manchester), M.Sc. (London), Ph.D.(McMaster)/Undergraduate AdvisorC~ David Rollo/B.Sc~, M.Sc. (Guelph), Ph.D. (British Columbia)Herbert E. Sc,tiellhorn/B.Sc., M.Sc. (Guelph), Ph.D. (North Carolina)l3ama S.Singh/B.Sc. (Agra),, M.Sc. (Kanpur), Ph.D. (California-Davis)EI,izabeth A. WeretilnyklB.Sc., Ph.D. (Alberta) ,Christopher M. Wood/B.Sc., M.Sc. (British Columbia), Ph.D. (East Anglia)FB.S.C.(SeniorCanadaResearch Chair. Associate ProfessorsChristian Baron/Dip!. Microbiol, Ph.D. (Munich) ,, Andre Beqard/B.Sc. (Montreal), Ph.D. (McGill)Robin K. Cameron/B.Sc. (Waterloo), Ph.D. (McGill)Ana Campos/B.A., M.A.' (Rio de Jan~iro), Ph.D. (Brandeis)'