Waters 2414 Refractive Index Detector

Table of ContentsCopyright notice .................................................................................................. iiiTrademarks ........................................................................................................... iiiCustomer comments ............................................................................................ ivContacting Waters ................................................................................................ vSafety considerations ........................................................................................... vSafety considerations specific to the detector.................................................... viSafety advisories ................................................................................................. viOperating this instrument ................................................................................ viiApplicable symbols ........................................................................................... viiAudience and purpose....................................................................................... viiIntended use of the Waters 2414 Refractive Index Detector.......................... viiCalibrating ........................................................................................................ viiQuality-control ................................................................................................. viiiISM classification ........................................................................................... i-viii1 Introduction ............................................................................................ 1-1Use of refractive index detectors .................................................................. 1-2Operating principles ........................................................................................ 1-2Optical refraction ............................................................................................. 1-2Differential refractometry ............................................................................... 1-7Common RI detection problems .................................................................... 1-10Detector description ...................................................................................... 1-11Range and attenuation .................................................................................. 1-11Features.......................................................................................................... 1-11Operation modes ............................................................................................ 1-13Flow path........................................................................................................ 1-15Fluid path components .................................................................................. 1-18Optics.............................................................................................................. 1-21Table of Contentsix