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The requirement to respect autonomy - The Royal New Zealand ...

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BACK TO BACKAll people over 75 years with a five-yearCVD risk of >15% should be treated withstatins unless specifically contraindicatedSue Wells MBChB,MPH(Hons), PhDSection of Epidemiologyand Biostatistics, Schoolof Population Health, <strong>The</strong>University of Auckland,Auckland, <strong>New</strong> <strong>Zealand</strong>YES‘I don’t think about my age. It’s only a number.’—James Biggs (104-year-old resident in a Dallasretirement community)This commentary addresses three questionsrelated <strong>to</strong> the health of older people:• What do we want <strong>to</strong> achieve?• How applicable are CVD risk prediction <strong>to</strong>ols?• What is the evidence for statin benefitand harm?Wells S. All people over 75years with a five-year CVDrisk of >15% should be treatedwith statins unless specificallycontraindicated—the ‘yes’case. J Prim Health Care.2010;2(4):330–332.Short answerOlder men and women—the grandparents ofour society, are treasures. As a group, they are atthe highest risk of CVD and, if they survive anevent, it may have considerable impact on theirquality of life and independence. Observationalstudies show that older people with favourableCVD risk fac<strong>to</strong>r levels are more likely <strong>to</strong> have ahealthier end of life as well as less life spent livingwith disability. Systematic reviews of primaryprevention trials demonstrate that statins willreduce CVD event rates by about 20% within fiveyears in people over 65 years, with little risk ofserious side effects. <strong>The</strong>re is no good evidencethat this will simply change their mode of death(i.e. <strong>to</strong> cancer). <strong>The</strong>refore, if elderly patients arethought <strong>to</strong> have a healthy life expectancy of fiveyears or more, those meeting guideline criteriafor statins should be offered them.What do we want <strong>to</strong> achieve?Ideally we want <strong>to</strong> delay the onset of illness anddisability, reduce the impact of morbidity andsupport our older patients <strong>to</strong> retain independenceand quality of life (QoL) as long as possible. <strong>The</strong>probability of death is 100%; the manner of livingprior <strong>to</strong> our dying is more negotiable.Cardiovascular disease (CVD) is a leading causeof death and healthy life years lost in <strong>New</strong><strong>Zealand</strong>. 1 While having a heart attack and dyingin your sleep may seem <strong>to</strong> be a good way <strong>to</strong> go,many people will not die in this manner. <strong>The</strong>prevalence of having had (and survived) a CVDevent rises exponentially after retirement age in<strong>New</strong> <strong>Zealand</strong>; 35% of 75-year-old women (45% ofmen) and 45% (50% of men) by the age of 80 yearswill have suffered an event. 2 <strong>The</strong> QoL for thosefollowing a myocardial infarction or stroke isBACK TO BACK this issue:Sue WellsDerelie ManginWhile evidence can help inform best practice, it needs <strong>to</strong> be placed in context.<strong>The</strong>re may be no evidence available or applicable for a specific patient withhis or her own set of conditions, capabilities, beliefs, expectations and socialcircumstances. <strong>The</strong>re are areas of uncertainty, ethics and aspects of care for whichthere is no one right answer. General practice is an art as well as a science. Qualityof care also lies with the nature of the clinical relationship, with communication andwith truly informed decision-making. <strong>The</strong> Back <strong>to</strong> Back section stimulatesdebate, with two professionals presenting their opposing views regarding a clinical,ethical or political issue.330 VOLUME 2 • NUMBER 4 • DECEMBER 2010 J OURNAL OF PRIMARY HEALTH CARE

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