Ch18 Amines(pdf) - KFUPM Open Courseware

Example: Ammonia gives a primary amine.Example: Primary amines give secondary aminesOH 2 , NiHCH 3 (CH 2 ) 5 CH+ H 2 NO + NH 3ethanolNH 2H 2 , Ni ethanol(80%)CH 3 (CH 2 ) 5 CH 2 NH(65%)via:NHExample: Primary amines give secondary aminesExample: Secondary amines give tertiary aminesOCH 3 (CH 2 ) 5 CH+ H 2 NOCH 3 CH 2 CH 2 CH+NH 2 , Ni ethanolH 2 , Ni, ethanolHCH 3 (CH 2 ) 5 CH 2 NH(65%)via:CH 3 (CH 2 ) 5 CHNNCH 2 CH 2 CH 2 CH 3(93%)