Schizophrenia Research Trends

112Stephen I. Deutsch, John Mastropaolo and Barbara L. SchwartzGibbs JW, Sombati S, DeLorenzo RJ, Coulter DA. Cellular actions of topiramate: Blockadeof kainite-evoked inward currents in cultured hippocampal neurons. Epilepsia. 2000; 41(Suppl. 1): S10-16.Goff DC, Henderson DC, Evins AE, Amico E. A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biological Psychiatry1999; 45(4): 512-514.Goff DC, Tsai G, Levitt J, Amico E, Manoach D, Schoenfeld DA, Hayden DL, McCarley R,Coyle JT. A placebo-controlled trial of D-cycloserine added to conventional neurolepticsin patients with schizophrenia. Archives of General Psychiatry 1999; 56: 21-27.Grimwood S, Slater P, Deakin JFW, et al. NR2B-containing NMDA receptors are upregulatedin temporal cortex in schizophrenia. NeuroReport 1999; 10: 461-465.Hirsch SR, Das I, Garey LJ, deBelleroche J. A pivotal role for glutamate in the pathogenesisof schizophrenia, and its cognitive dysfunction. Pharmacology Biochemistry andBehavior 1997; 56: 797-802.Humphries C, Mortimer A, Hirsch S, de Belleroche J. NMDA receptor mRNA correlationwith antemortem cognitive impairment in schizophrenia. Neuroreport 1996; 7(12): 2051-2055.Huntsman, MM, Tran BV, Potkin SG, Bunney WE Jr, Jones EG. Altered ratios ofalternatively spliced long and short gamma 2, subunit mRNAs of the gamma-aminobutyrate type A receptor in prefrontal cortex of schizophrenics. Proceedings of theNational Academy of Sciences USA 1998; 95: 15066-71.Ishimaru M, Kurumaji A, Toru M. Increases in strychnine insensitive glycine binding sites incerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis. BiologicalPsychiatry 1994; 35: 84-95.Javitt DC, Balla A, Sershen H, Lajtha A. Reversal of phencyclidine-induced effects byglycine and glycine transport inhibitors. Biological Psychiatry 1999: 45(6): 668-679.Jentsch JD, Roth RH. The neuropsychopharmacology of phencyclidine: from NMDAreceptor hypofunction to the dopamine hypothesis of schizophrenia.Neuropsychopharmacology 1999; 20(3): 201-225.Jentsch JD, Taylor JR, Roth RH. Subchronic phencyclidine administration increasesmesolimbic dopaminergic system responsivity and augments stress- andpsychostimulant-induced hyperlocomotion. Neuropsychopharmacology 1998: 19: 105-113.Long KD, Mastropaolo J, Rosse RB, Deutsch SI. Exogenously administered D-serine failedto potentiate the ability of MK-801 to antagonize electrically precipitated seizures innonhandled control and stressed mice. European Neuropsychopharmacology, in thepress.Long KD, Mastropaolo J, Rosse RB, Manaye KF, Deutsch SI. Modulatory effects of D-serineand sarcosine on NMDA receptor-mediated neurotransmission are apparent after stress inthe genetically inbred BALB/c mouse strain. Brain Research Bulletin 2006; 69: 626-630.Martin R, Kuznjiecky R, Ho S, Hetherington H, Pan J, Sinclair K, Gilliam F, Faught E.Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.Neurology 1999; 52: 321-327.