The Genetic Basis of White Tigers - abc
The Genetic Basis of White Tigers - abc
The Genetic Basis of White Tigers - abc
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Alternative Strategy13 <strong>of</strong>fspring tigers (F 1 )RAD sequencing and SNP detectionSNP markers3 parental tigers (F 0 )Genome-wide linkage mappingTrait-associated chromosome regionsWhole-genome sequencingGWASLD and haplotype analysisBoundary <strong>of</strong> candidate genome regionGenome sequence andpolymorphisms between genomesMutationscreeningSearching for candidate mutationsin the candidate regionCandidate genes with non-sysnonymous mutationsCausative gene and mutation siteValidation and extended study in 130unrelated tigers (20 white and 110 wild-type)Functional characterization
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