—762 Uijj/Uheria. [November,VII. The simple form is easily controlled by treatment whichis the same as for the severe form, modified according to thecomparative urgency of the case.VIII. The severe form is with difficulty controlled, <strong>and</strong> theprognosis is always extremely unfavorable, even at the begining.IX. The treatment is the local '-application of hydrochloricacid, diluted or not; solution of nitrate of silver, one or twoscruples to the ounce of distilled water; strong solution of sulphateof copper, drachm <strong>and</strong> a half to the ounce of water ;concentratedsolution of the perchloride of iron ;Monsel's Salt, inpowder; solution of chloride of sodium, etc., according to theeducated judgment of the physician.Externally—strict cleanliness ;in the first stage of the disease,while the engorgement is red <strong>and</strong> hot, cold, wet compresses appliedto the neck, <strong>and</strong> often repeated, can scarcely fail to relieve,at least for a time. Farther along, when the engorgement ofthe throat becomes oedeinatous, warm fomentations should besubstituted. Never liniments, mustard, nor anything of thekind; for these appliances increase the anguish of the patient,<strong>and</strong> do not mitigate the affection.Internally—first, a thorough emetic of ipecacuanha, given infull dose <strong>and</strong> largely diluted, so as to be vomited immediately.This should be repeated daily for the first two or three days.The bowels should be moved once a day by glysters, if possible;if not, by some mild laxative. Drastic cathartics shouldbe carfully avoided. Iced milk <strong>and</strong> water, or iced gum-water,or iced infusion of ulrnus fulva, should be given in minutequantity, frequently as the patients desire. These iced fluidswill be found very grateful to them.Quinine in small doses, say from one-fifth to one-half of agrain, often repeated, should materially assist in the tonic treatmentuniversally recommended.* The mixture of " sesquichlointhe propagation of Diphtheria. There is in this country, a great deal of skepticismas to the contagious character of this disease ; but the mass of evidenceto prove it is overwhelming. Thus Bretonneau has collected some crucial cases.One is that of M. Herpin, Surgeon to the Hospital at Tours, <strong>and</strong> Professor at theschool. A child seized with Diphtheria, who had transmitted the disease alreadyto its nurse, was placed under his care; <strong>and</strong> at one of his visits, by access ofcough, part of the diphtheritic matter was ejected from the mouth, while theprocess of sponging the pharynx was being performed, <strong>and</strong> it lodged on the apertureof the nostril of M. Herpin. Occupied with his task, he neglected for a momentto remove it. A severe Diphtheritic inflammation of the part ensued,which spread over the whole nostril <strong>and</strong> pharynx. Extreme constitutional disturbanceoccurred, <strong>and</strong> the prostration was so severe, that convalescence occupiedmore than six months. Dr. Gendren, of Chateau de Loire, received a showerof tracheal Diphtheric exudations, expelled by a young patient during anaccess of coughing. Laryngeal Diphtheria set in, with urgent symptoms.Prompt measures saved him. Lancet, April, 1859, p. 288.* Of the many internal remedies which have been advised, we do not know ofany on which so much reliance can be placed as on the tincture of sesquichloride
—:1859.] Diphtheria. 763ride of iron with chlorate of potass, chloric ether, <strong>and</strong> hydrochloricacid sweetened with syrup," may be employed by thosewho fancy many not incompatible compounds in one conglomerate.But care must be used not to give this mixture with themilk <strong>and</strong> eggs recommended in the same paragraph of the Lancet'sCommission ; <strong>and</strong> yet it is hard to see how this could beavoided, if all are to be given " frequently." I would suggestanother remedy combining tonic, nutriment, <strong>and</strong> stimulusferruginated cod-liver oil <strong>and</strong> br<strong>and</strong>y, in the proportion of twofluid drachms of the former to one of the latter, repeated four orfive times a day, or ofteuer, if the stomach will bear it.I believe chlorate of potash harmless, but of unproved efficacyin diphtheria. I have employed it, but saw no results exceptmitigation of fcetor of expiration, when the false membranewas in the stage of decomposition. Charcoal, chloride of soda,etc., perhaps act in a similar manner. Ablation of the tonsilsat the beginning of the disease, it appears to me, cannot be toostrongly insisted upon. Tracheotmy cannot be ignored, butshould be resorted to where other means fail to relieve thecyanosis, <strong>and</strong> suffocation is imminent from obstruction of thefauces <strong>and</strong> larynx, or even the fauces alone, the larynx beingintact. In this latter condition, tubing the larynx should firstbe attempted.It is less difficult to prevent this disease than to cure it. Themost scrupulous cleanliness of persons <strong>and</strong> surroundings, free <strong>and</strong>constant ventilation, should be insisted on. If there are manychildren, <strong>and</strong> the rooms are small, as frequently happens in familieswhere this disease appears, the well ones should be sent away,if possible ; <strong>and</strong> if not, kept out of the room in which the infectedchild lies. M. Duche insists on the free use of sulphur as aprophylactic : he says, those children who took sulphur werenot attacked, in any case ;while others, under the same circumstances,fell victims to the malady. It is a simple, harmlessremedy, <strong>and</strong> should be tried as a preventive. M. Duche maybe right.Finally, all our knowledge of this disease may be thus epitomized.1. Diphtheria is a specific, new, zymotic disease.2. Its diagnostic sign is an aplastic membranous exudation.of iron, with chlorate of potass, chloric ether, <strong>and</strong> hydrochloric acid, ia the formof mixture, sweetened with syrup; full doses being employed, according to theage of the patient, <strong>and</strong> frequently repeated. A. free use should be male of generouswine, beef-tea, coffee, eggs in combination with br<strong>and</strong>y <strong>and</strong> wine, milk,<strong>and</strong> whatever other form of nutriment the ingenuity of the surgeon or the fancyof the patient can suggest. When food is refused, then enemata similarly composedmust be administered frequently, in small quantities of two ounces <strong>and</strong>upward, that they may not be rejected; for it is of the first importance that inanitionshould not open the last portals of life to the advancing disease. LancrtCommission.ff.S. VOL. XV. NO. XI. 54
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