Southern Medical and Surgical Journal - Georgia Regents University

—1859.] Cancerous Ulceration close to the inner Canthus. 771but that the recon traction becomes more severe than before.As I had not the opportunity of seeing this gentleman beforehe was cut, I cannot positively state whether this holds goodhere or not; but that the induration still remained, or had reformedat the site of the old disease, was quite evident by runningthe finger along the perineum. Cutting cannot possibly get ridof this ;and so long as this remains, the stricture will persist.London Med. Times and Gaz..Cancerous Ulceration close to the inner Canthus, treated with Sulphateof Zinc Paste.Dr. William Mackenzie, of Glasgow, relates the followinginteresting and instructive case. A patient, aged apparentlyabout forty -five, and who attributed the spread, if not the origin,of his complaint, to the depression of mind arising from pecuniaryloss, applied to me on the first of February, 1859, on accountof a cancerous ulcer on the side of the nose, close to the innerangle of his left eye. It was fully the size of a four-pennypiece, of irregular shape, covered with a scab, and surroundedoy hard and elevated edges. The papillae and carunculae lacrymales,and the palpebral conjunctiva were inflamed, and thedisease seemed to be extending in the direction of these structures.I felt no doubt, that were the nicer left to itself, it wouldgradually spread, and prove rebellious to all applications of asoothing description. Having repeatedly found, also, that extirpationof such a disease by the knife, even when care wastaken to cut into the sound integuments, although followed bya firm cicatrix and an apparent cure, was succeeded after a timeby a renewal of the scirrhous hardness and intractableulceration.I determined in this case to try as an escharotic, the sulphateof zinc, as recommended by Dr. Simpson, of Edinburgh.I was partly led to this course, too, by observing that I couldnot extirpate the diseased part without removing the lowerpapillae lacrymalis.Having driven off by heat, the water of crystalization of afew grains of the sulphate of zinc, and reduced the residuum toa fine powder, I mixed it with a little glycerine, so as to form athick tenacious paste. Taking a little of this on the point of abit of stick, I appllied it over the scab and over the hard edgesof the ulcer, and covered the part with dry lint.Next day, I found that the application had given very littleuneasines ; out that it had acted in destroying almost entirelythe hard edges of the sore, and left the whole of its surface freefrom scab and of a florid healthy color.