—774 Cases of Suppression of the Urine. [November,to find means to destroy this obstacle. For this end, M. Roussetapplied, first, crayons of nitrate of silver, then the nitricoxide of mercury. This last means, continued during twentyfivedays, with much care, caused very smart pain. Like thepreceding, it was not followed by any advantageous effects.Tincture of iodine had no good result.On the 6th of Juh r ,after all these failures, Prof. Rousset hadrecourse to the use of chromic acid. He made application of asolution prepared as follows: R. Chromic acid, 1 part; aquaedistilled., 3 parts. By the employment of a pencil, each excrescencewas separately washed with this liquid, having care notto touch the mucous membrane that surrounded it. The patientexperienced immediately, in the part touched by the solution,a sensation of smarting <strong>and</strong> pain, which was calmed againdirectly. Redness was manifested, a little swelling, in short aslight inflammation, which was terminated by the formation ofpus. Some few washings with Goulard's water, <strong>and</strong> the use ofdry lint, constituted the whole treatment. In proportion assuppuration was established, the excrescences were detached,disappearing, <strong>and</strong> leaving in their place a reddish surface, insome points excoriated, in others ulcerated, very superficially.The cicatrization was regularly <strong>and</strong> uniformly established.July 20th, the cure was complete ; the cervix uteri, the labiamajora <strong>and</strong> minora, <strong>and</strong> the vagina, were entirely freed fromthese adventitions productions, <strong>and</strong> offered an aspect which wasaltogether normal.On the 26th accouchement took place without any accident.The child of the masculine gender, was perfectly formed, <strong>and</strong>afforded no traces on its body that could cause the mother to besuspected of any affection of a specific nature.The chromic acid has been extolled, these few years past, asa caustic, both by Dr. Keller, of Germany, <strong>and</strong> by Dr. Marshall,of London, for destroying vegetations developed on the genitalparts. Dr. Marshall uses the acid in solution. Dr. Keller appliesit in the form of paste. Whatever process is adopted, thiscaustic is easily managed ; its action is at the same time veryrapid, little painful <strong>and</strong> thorough. We have a right to conclude,then from this case, that in these excrescences the chromic acidis a powerful caustic, <strong>and</strong> preferable to others that have beenhitherto employed. [Caussade of the School of Bordeaux, <strong>and</strong>Boston Med. <strong>and</strong> Surg. <strong>Journal</strong>.Cases of Suppression of the Urine. By James Alex<strong>and</strong>er, Esq.,Surgeon, Wooler.The pathology of the disease, described by our older writersunder the name of ischuria renalis, is little known, <strong>and</strong> the dis-
1859.] Gases of Suppression of the Urine. 775ease itself is a very rare one. Dr. Abercrombie treats of suppressionof urine as resulting sometimes from disease of the kidneyitself; sometimes from disease, generally inflammatory, ofsome adjacent organ ; <strong>and</strong> only very occasionally as proceedingfrom some unknown cause affecting the nerves of the organ, <strong>and</strong>leaving few or no morbid traces after death. The same view,substantially, is taken by recent systematic writers; with astrong inclination, perhaps,, to refer all, or almost all, cases ofsuppression to some stage or modification of granular disease ofthe kidney. I cannot pretend to throw any light on the intimatenature of the disease ;nor have I the means of going intothe literature of it. But, perhaps the two following cases, whichoccurred to me very recently, may possess sufficient interest todeserve being recorded in the Edinburgh <strong>Medical</strong> <strong>Journal</strong>:—On the 13th February last, I was requested to visit a shepherdlad,appeared to be laboring under the symptoms of ordinary continuedfever, which his friends imagined had been brought onby cold <strong>and</strong> exposure to wet. He had been ill about ten days.His pulse was about 100 ; his tongue loaded, <strong>and</strong> his throatslightly inflamed <strong>and</strong> painful; he complained of headache, buthad little delirium ; there was a good deal of restlessness, <strong>and</strong>his urine was scanty <strong>and</strong> high-colored ;there was no cutaneouseruption. He was ordered some mild aperient, his diet carefullyregulated, <strong>and</strong>, as his pulse was weak, a small quantity ofwine was directed to be taken at intervals. On the 15th, thesymptoms were nearly the same, but the quantity of urine wasaged 16, residing about seven miles from Wooler, whovery much diminished ; on the 16th, totally suppressed ; <strong>and</strong>about midnight of the 17th, he died, just a few minutes beforeI entered the house. Before his death there was partial stupor,but no profound coma, <strong>and</strong> slight irregular movements of themuscles of the face <strong>and</strong> eyes, but no general convulsions.Five weeks afterward, I was sent for to see a younger brother,who was reported to be ill of the same disease of which the firstbrother had died. I learnt that, in the interval between thedeath of the elder brother <strong>and</strong> the seizure of the one I was nowvisiting, a sister had been ill, as the people supposed, of thesame disease, but had passed through it so mildly that no medicaladvice had been sought for her. My present patient exhibitedsimilar symptoms to those presented by his brother; hehad been ill seven days; there was headache, slight sore throat,great general uneasiness, <strong>and</strong> already the same noticeable diminutionin the quantity of water voided was beginning to manifestitself; there was also some spots on the abdomen resemblingthe eruption of typhoid fever ; but as the youth was liable toan anomalous rash in the spring months, I would not lay muchstress on that symptom. The following day the pulse had fill-
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