—764 Atropine in Epilepsy. [November,3. The indications of treatment are to remove the exudation,<strong>and</strong> prevent its re-formation.4. The treatment is tonic, antiseptic, stimulant, <strong>and</strong> nutritious.5. The means of prevention are cleanliness,- pure air, freeliving, <strong>and</strong> possibly sulphur taken internally.Conclusion.—Diphtheria is the most,* certainly fatal epidemicthat ever visited our race ;but it is not de natura sua incurable.American Med. Monthly.Atropine in Epilepsy.Dr. Max. Maresch, availing himself of his position as physicianof an establishment for the insane, at Vienna, has submittedsome epileptic patients to the influence of atropine, <strong>and</strong> haspublished the results in the Vienna <strong>Journal</strong> of Medicine. Dr.Maresch's experiments were made upon eight patients in thefemale department, <strong>and</strong> ten more in the department of the incurableinsane ; four of these were men, <strong>and</strong> six women.Of the ei^ht first patients, three were completely cured, <strong>and</strong>the condition of the five others so notably ameliorated, that itwas impossible to deny the beneficial effect of the atropine. Ofthe ten patients belonging to the class of incurables, eight experienceda marked diminution in the violence <strong>and</strong> frequency oftheir epileptic attacks, as well as in the exacerbations of theirphysical troubles. These results, united to those obtained byothers in the treatment of epilepsy by atropine, merit seriousattention.Maresch has carefully noted the therapeutic phenomenawhich have arisen during the administration of this remedy.One-fiftieth of a grain of atropine, gave rise, in every case, toeffects which habitually follow the administration of this agent,such as dryness of the throat, difficulty in articulating, visualaberration, dilatation of the pupils, etc.; phenomena to whichby degrees the patients become habituated, which, however, donot cease during the entire treatment. In every case the pulselost eight or twelve pulsations during the first hour after takingthe remedy, but the pulse resumed its normal frequency so soonas the other therapeutic phenomena manifested themselves.There did not occur, in any case, a marked <strong>and</strong> permanent accelerationof the pulse, under the influence of the dose aboveindicated. As special phenomena, Maresch observed in thosecases while under the influence of atropine, an exanthem analogousto roseola, which soon disappeared under the influence ofwarm baths <strong>and</strong> the discontinuance of the remedy. It is, besides,worthy of remark, that atropine did not give rise, in any
——1859.] Diarrhoea of Infants at the Breast. 765case, to digestive derangement, or any other unfavorable symptom.The administration of this remedy has not proved beneficialin the other forms of mental diseases. Dr. Maresch administersatropine as follows: he dissolves a grain of it in five hundreddrops of rectified alcohol, <strong>and</strong> of this solution he gives from fiveto ten drops, (from ong-hundredth. to one thirtieth of a grain.)This dose is administered once, in the morning before breakfast,from which coffee, tea, <strong>and</strong> chocolate must be excluded, as thesesubstances interfere with its action. This is continued from sixtyto ninety days, without interruption, then is to be resumedafter an interval of from thirty to forty-five days. With women,there is no need to suspend its administration during menstruation,as it favors <strong>and</strong> augments this discharge. Barely doesatropine give rise to constipation, more frequently to diarrhoea,which necessitates, when it becomes severe, a suspension of itsadministration for some days. Translated from L Union Medicate,by s. E. c. American Med. Monti dy.Reflections upon the Use ofRaw Meat in the Colliquative Diarrhozaof Infants at the Breast. By Dr. J. ¥. Weisse, Director ofthe Hospital for Children, at St. Petersburg.JL period of seventeen years has elapsed since the attention ofmy confreres was called to the great value of this remedy inthis disease, but it did not come into general use until five yearslater, <strong>and</strong> after the publication of more extensive works upon thesubject. About this time, Dr. Behrend, of Berlin, addressed mea letter which contained the following passage: "You cannotimagine how much interest your communication upon the treatmentof the colliquative diarrhoea of infants at the breast, byraw meat, has excited ;we now use it exclusively in this disease."Soon after, Dr. Behrend inserted in the sixth volume of hisjournal, a letter from M. Marotte, Physician of the Central Officeof the Hospitals of Paris, addressed to Professor Trousseau, inwhich the author gave a theory to account for the results which.I had obtained. From this latter time, the treatment by rawmeat has been generally admitted everywhere, <strong>and</strong> its utility hasbecome incontestable.Among the numerous favorable reports recently published, Iwill cite that of Dr. Eichelberg: "In consequence of the shorttime which has passed since this treatment was recommended, Ihave by me only a limited number of observations, (twenty,)but all prove its efficiency. The cases in which infants refuseraw meat are very rare ; the majority swallow it with avidity.I have observed two cases which were very striking ; in these
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