2011-2012 Catalogue - PeproTech, Inc.

www.peprotech.com2011-2012 CatalogueTGF-β SuperfamilyNatural Antagonists/Name Synonyms Main Function Binding ProteinsINFORMATION & TECHNICAL SUPPORTTGF-β 1Differentiation inhibiting Regulates cell proliferation, growth, differentiation Follistatin, Follistatinfactor, cartilage-inducing and motility. Involved in adipogenesis, -like related genefactor chondrogenesis, embryogenesis, tissue remodeling, (FLRG), Decorin,wound healing and tumor formation.alpha-2macroglobulinTGF-β 2Glioblastoma-derived Regulates cell proliferation, growth, differentiation Decorin, alpha-2T-cell suppressor factor, and motility. Involved in adipogenesis, macroglobulinBSC-1, Cetermin,chondrogenesis, embryogenesis, tissue remodeling,Polyerginwound healing and tumor formation.TGF-β 3None Regulates cell proliferation, growth, differentiationand motility. Involved in adipogenesis,chondrogenesis, embryogenesis, tissue remodeling,wound healing and tumor formation.TGF-β 4Endometrial bleeding asso- Essential for left-right (L-R) asymmetryciated factor beta-4, (EBAF) determination of organ systems. Possible role inLefty preproprotein, LEFTA endometrial bleeding.Inhibin A Inhibin alpha & beta A Inhibits secretion of follitropin by the pituitarygland, regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic,pituitary and gonadal glands.Inhibin B Inhibin alpha & beta B Inhibits secretion of follitropin by the pituitarygland, regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic,pituitary and gonadal glands.Activin A Activin beta-A, Inhibin Regulates embryogenesis, osteogenesis, Follistatin,beta-1, FRP, (Follicle- hematopoiesis, reproductive physiology and Follistatin-likestimulating hormone- hormone secretion from the hypothalamic, pituitary related gene (FLRG),releasing protein),FSH- and gonadal glands. GASP-1, Cerberus,releasing protein, FSH-DAN, alpha2releasing factor, EDFmacroglobulin.(Erythroid differentiation factor)Activin AB Activin beta A & beta B Regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin B Activin beta-B, Inhibin Regulates embryogenesis, osteogenesis,beta-2hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin C Activin beta-C, Inhibin Regulates embryogenesis, osteogenesis,beta-C, blastocyst B1 hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin E Activin beta-E, Regulates embryogenesis, osteogenesis,inhibin-beta Ehematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.BMP-2 BMP-2A Induces cartilage and bone formation, plays a Noggin, Chordin,role in cardiac morphogenesis.Follistatin,Follistatin-like relatedgene (FLRG), DAN,Cerberus, GremlinBMP-3 Osteogenin Induces cartilage and bone formation.146To Order: EC: Tel: +44 (0)20 7610 3062 • email: info@peprotech.co.ukBestellungen: AUSTRIA: Tel: +43 (0)1 405 9696 • email: info@peprotech.atObjednávky: Česká Rep.: Tel: +420 225 992 284 • email: info@peprotech.cz