2011-2012 Catalogue - PeproTech, Inc.

PEPROTECH ®www.peprotech.comAntagonists of TGF-β LigandsNatural TGF-β Antagonists Structural Features Contained in the Known TGF-β BindingAntagonist Polypeptide (M.W.)PartnersNoggin unique Noggin cysteine knot (26 kDa) BMP-2,-4,-5,-6,-7,-13/GDF-6,-14/GDF-5Chordin 4 CR/VWCC (Chordin) domains, BMP-2,-4,-73 SOG repeats (102 kDa)Chordin-like/Neuralin/Ventroptin 3 Chordin domains (51 kDa) BMP-4,-5,-6Follistatindomains (38 kDa)3 cysteine-rich Follistain (FS) and 3 kazal activin, BMP-2,-4,-6,-7, myostatin/GDF-8,GDF-11, TGFβ-1Follistatin-like related gene 2 FS and 2 kazal domains (28 kDa) activin, myostatin/GDF-8, GDF-11, TGFβ-1(FLRG)GASP-1 1 Wap, 1 FS, 1 kazal, 1 IG-like, myostatin/GDF-8, GDF-112 kunitz, 1 netrin domains (63 kDa)Follistatin-related protein 1 FS, 1 CR/VWRC, activin, BMP-2,-6,-7(FSRP)2 EF-hand domains (35 kDa)DAN unique DAN cysteine knot (19 kDa) BMP-2,-4,-7, -14/GDF-5Cerberus DAN-like cysteine knot (30 kDa) BMP-2,-4,-7, activin, nodalGremlin DAN-like cysteine knot (21 kDa) BMP-2,-4,-7Sclerostin/SOST unique Sclerostin cysteine knot (24 kDa) BMP-5, -6Decorin multiple leucine-rich repeats (40 kDa) TGFβ-1, -2alpha-2 macroglobulin multiple proteinase inhibitor domains TGFβ-1, -2 , activin, inhibin(163 kDa)Note: This table is reflective of the current knowledge.INFORMATION & TECHNICAL SUPPORTBestellungen: Deutschland: Tel: 0800 436 99 10 • email: info@peprotech.dePour commander: France: Tel: +33 (0)1 46 24 58 20 • email: info@peprotechfr.comTo Order: NORDIC: Tel: +46 (0)8 640 41 07 • email: info@peprotech.se149