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Acute Hepatitis Including Acute Liver Failure

Acute Hepatitis Including Acute Liver Failure - Virtual Pathology at ...

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Autoimmune <strong>Hepatitis</strong> - <strong>Acute</strong> Presentation<br />

Histological Features<br />

<strong>Acute</strong> hepatitis (with no signs of chronic liver disease)<br />

(Hofer 2006, Te 1997, Singh 2002, Hofer 2006, Ichai 2007, Miyake 2010, Fujiwara 2011,<br />

Stravitz 2011, Susuki 2011, Yasui 2011)<br />

– Classical features of acute lobular hepatitis<br />

– Mainly centrilobular distribution (central perivenulitis)<br />

• Often associated with centrilobular necrosis<br />

– Some cases initially have little or no portal inflammation, before<br />

subsequently progressing to more classical features of chronic AIH

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