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Acute Hepatitis Including Acute Liver Failure

Acute Hepatitis Including Acute Liver Failure - Virtual Pathology at ...

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<strong>Acute</strong> versus Chronic Damage<br />

Severe <strong>Acute</strong> <strong>Hepatitis</strong> (e.g. case 2)<br />

• Areas of bridging necrosis & nodular regeneration can resemble changes occurring<br />

in cirrhosis<br />

• Areas of multiacinar necrosis can resemble inflamed fibrous septa in cirrhosis<br />

<strong>Acute</strong> versus Chronic Damage - Helpful pointers<br />

• Clinical context<br />

• Identification of normal vascular relationships<br />

• Use of connective tissue stains to determine age of lesions

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