Acute Hepatitis Including Acute Liver Failure

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Autoimmune Hepatitis - Acute Presentation Histological Features Acute hepatitis (with no signs of chronic liver disease) (Hofer 2006, Te 1997, Singh 2002, Hofer 2006, Ichai 2007, Miyake 2010, Fujiwara 2011, Stravitz 2011, Susuki 2011, Yasui 2011) – Classical features of acute lobular hepatitis – Mainly centrilobular distribution (central perivenulitis) • Often associated with centrilobular necrosis – Some cases initially have little or no portal inflammation, before subsequently progressing to more classical features of chronic AIH
Case 1- outcome • Treatment with corticosteroids and azathioprine • Prompt resolution of liver dysfunction • Negativity of autoantibodies • Reduction of immunosuppression ‣ mild biochemical relapse ‣ reappearance of autoantibodies
Page 1 and 2: Acute Hepatitis Including Acute Liv
Page 3 and 4: Acute Liver Failure (ALF) FHF and L
Page 5 and 6: Acute Liver Failure Admissions Birm
Page 7 and 8: Acute Liver Injury Establishing the
Page 9 and 10: Acute Liver Injury Establishing the
Page 11 and 12: Case 1
Page 13 and 14: Liver Biopsy in Acute Hepatitis His
Page 17 and 18: Case 1 - ductular reaction CK7 immu
Page 21 and 22: Case 1 (PAS-diastase)
Page 23 and 24: Acute Hepatitis Hepatocyte Prolifer
Page 25 and 26: Case 1 (HVG)
Page 27 and 28: Case 1 Diagnosis • Acute hepatiti
Page 29: Autoimmune Hepatitis - Acute Presen
Page 33: Case 2 LIVER BIOPSY
Page 39 and 40: Case 2 - outcome • Mild encephalo
Page 41 and 42: Case 2. Macroscopic Appearances Shr
Page 46 and 47: Could this be cirrhotic?
Page 51 and 52: Other Changes Seen in Areas of Pare
Page 53 and 54: Hepatectomy Specimen - Case 2 Histo
Page 55 and 56: Role of Liver Biopsy in Acute Hepat
Page 57 and 58: Acute versus Chronic Damage Severe
Page 59 and 60: Liver Cell Death in Acute Hepatitis
Page 61 and 62: Acute Hepatitis - Common Causes 1.
Page 63 and 64: Acute Hepatitis - Aetiological Cons

Acute Hepatitis Including Acute Liver Failure

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