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Acute Hepatitis Including Acute Liver Failure

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Case 2<br />

• 67 year old Caucasian male<br />

• 1 to 2 week history of jaundice and abdominal distension<br />

• ALT 1011, bilirubin 220, INR 2.0<br />

• viral serology negative<br />

• autoantibodies negative, immunoglobulins normal<br />

• US scan<br />

‣ small liver<br />

‣ ascites ++<br />

‣ spleen not enlarged<br />

• Diagnosis: aetiology and severity<br />

‣ acute seronegative hepatitis<br />

‣ severe (small liver with ascites)<br />

‣ poor prognosis for recovery<br />

• <strong>Liver</strong> biopsy

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