Database on medicinal plants used in ayurveda - AYUSH Research ...

epoxy-2-hydroxy-3, 7(11)-guaiadien-12, 8-olide, (-)-clusin, (-)-yatein,
ethoxyclusin, and (-)-dihydroclusin (Usia et al., 2005).
Fruits: (–)Cubebin (Prabhu and Mulchandani, 1985; Batterbee et al.,
1969a), (–)clusin, (–)hinokinin, asaronaldehyde, (–)deoxypodorhizon
(Koul et al., , 1983), (–) dihydrocubebin (Dwuma-Badu et al., 1975),
(2R, 3R) -2-(3�, 4�, 5�-trimethoxy benzyl)-3-(3�, 4�-methylenedioxybenzyl)-1,
4-butanediol (–)-dihydroclusin, (3R, 4R)-3, 4-bis-(3, 4,
5-trimethoxybenzyl)tetrahydro-2-furanol [(–)-cubebinin], (–)-yatein (Prabhu
and Mulchandani, 1985), �-O-ethyl cubebin, �-ethylcubenin,
dihydrocubenin monoacetate, 5�-methoxythiokinin (Badheka et al., 1987),
cubebin (Chatterjee et al., 1968; Batterbee et al., 1969b), (–)cubebininolide
(cordigerine), (–)-2-(3”, 4”-methylenedioxybenzyl)-3-(3‟,
4‟-dimethoxybenzyl)butyrolactone, (–)-isoyatein, (–)-cubebinone and (–)di-O-methyl
thujaplicatin methyl ether (Badheka et al., 1986), bisasarin
(Yuan et al., 1982), cubebinic ether, cubebinol, isocubebinic ether,
hibalactone, dehydrocubebin, isohinokinin, (+) – hinokinin (Batterbee et
al., 1969b).
Essential oil: Sesquiterpene hydrocarbons-bicyclosesquiphellandrene, 1epibicyclosesquiphellandrene,
zonarene, calamenene, epizonarene, �cadinene,
cubenene, �-muurolene (Terhune et al., 1974).
Seed oil: Palmitic, linolic, oleic, linolenic, stearic, arachidic, behenic
and hexadecenoic acids (Bedi et al., 1971), cubebol, cubebic acid,
piperidine, sesamin (Prabhu and Mulchandani, 1985).
PHARMACOLOGICAL ACTIVITIES
Plant was reported to have antibacterial (Kar and Jain, 1971; Jain et al.,
1974), anti-inflammatory, antinociceptive (Choi and Hwang, 2003),
antifungal (Rao and Nigam, 1976), anthelmintic (Sharma et al., 1979),
antidysenteric, antiasthmatic, diuretic, carminative, sedative, antiseptic,
activity against hepatitis crisus (Hussein et al., 2000) and antioxidants
(Karthikeyan and Rani, 2003) activities.
The essential oil of P. cubeba showed antibacterial activity against B.
subtilis, V. cholerae, etc. The oil had no appreciable effect on E. coli, S.
aureus, S. lutea and Micrococcus sp (Kar and Jain 1971; Jain et al., 1974;
Rao and Nigam, 1976).
The oil of P. cubeba also showed significant antifungal activity against
Aspergillus flavus, A. fumigatus, Trichoderma virid, Curvularia lunata,
Alternaria tenuis, Penicillium sp, P. javanicum, P. striatum and Fusarium
solani (Rao and Nigam, 1976).
175