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Database on medicinal plants used in ayurveda - AYUSH Research ...

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methylcholesta–5-trans-22-diene-3�-ol), dehydrocompesterol (24�-methyl<br />

cholestas-trans-22-diene-3�-o1), campesterol (24�-methyl cholest-5-en-3�ol),<br />

sitosterol and 5-dehydro-avenasterol (Matsumoto et al., 1983).<br />

Seed epidermis: Arab<strong>in</strong>ose, rhamnose, glucose, mannose, galactose, �-Dgalactopyranosyl-(1�6)-O-�-D-galactopyranosyl-(1�1)-L-myo<strong>in</strong>ositol<br />

arab<strong>in</strong>an (Siddiqui et al., 1973), S-1-methoxy-1- (3,5-dimethoxy-4hydroxyphenyl)<br />

ethane, <strong>in</strong>dolacet<strong>on</strong>itrite, 4-hydroxy <strong>in</strong>doleacet<strong>on</strong>itrile, 4hydroxyphenyl<br />

acet<strong>on</strong>itrile (Nagatsu et al., 2004), rut<strong>in</strong> (Francois, 1960) and<br />

epi-progoitr<strong>in</strong> (Aust<strong>in</strong> et al., 1968), brassicasterol, 22-dehydrocampesterol<br />

(Matsumoto et al., 1983), (S)-3-Hydroxypent-4-enethi<strong>on</strong>amide and (R)-3-<br />

Hydroxypent-4-enethi<strong>on</strong>amide (Aust<strong>in</strong> et al., 1968).<br />

PHARMACOLOGICAL ACTIVITIES<br />

Plant was found to be have rubifacient (Agarwal, 1997), anti-<strong>in</strong>flamatory,<br />

antiscorbutic, antibacterial, antifungal, fungitoxic and antioxidative (Nagastu<br />

et al., 2004) activities.<br />

TOXICOLOGY<br />

The glucos<strong>in</strong>olates and its derivatives are resp<strong>on</strong>sible for the toxicity. The<br />

glucos<strong>in</strong>olates split up<strong>on</strong> enzymatic hydrolysis to produce sulphur c<strong>on</strong>ta<strong>in</strong><strong>in</strong>g<br />

compounds. After <strong>in</strong>tramolecular rearrangement they give rise to<br />

isothiocyanates, thiocyanates, nitriles which are more toxic (An<strong>on</strong>ymous,<br />

1988).<br />

THERAPEUTIC EVALUATION<br />

50 known patients of br<strong>on</strong>chial asthma were tested for resp<strong>on</strong>se to comm<strong>on</strong><br />

allergens like, pollen, fungi, dust, mites by sk<strong>in</strong> test. The most comm<strong>on</strong><br />

pollen allergens were found to be Holoptelia <strong>in</strong>tegrifolia (36%), Carica<br />

papaya (36%), Brassica campestris (32%) (Dabaniya et al., 1999).<br />

FORMULATIONS AND PREPARATIONS<br />

Asava and Arista – Ayaskriti.<br />

Guggulu – Maha Yogaraja Guggulu.<br />

Taila – Maricadya taila, Kumkumadi taila, Somaraji taila, Dashmoola taila,<br />

H<strong>in</strong>gvadi taila, Karpasathydi taila, Prabhanyana vimardana taila.<br />

Lepa – Sarsapadi Pralepa (An<strong>on</strong>ymous, 1978; 2000).<br />

TRADE AND COMMERCE<br />

Retail market price: Seed Rs. 40 /kg. Seed oil – Rs. 65 per litre.(2006).<br />

314

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