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SAS/STAT 922 User's Guide: The MIXED Procedure (Book Excerpt)

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4530 ✦ Chapter 56: <strong>The</strong> <strong>MIXED</strong> <strong>Procedure</strong><br />

If H k is singular, then PROC <strong>MIXED</strong> uses the following relative criterion:<br />

g 0<br />

k g k<br />

jf kj<br />

number<br />

To prevent the division by jf kj, use the ABSOLUTE option. <strong>The</strong> default convergence criterion<br />

is CONVH, and the default tolerance is 1E 8.<br />

COVTEST<br />

produces asymptotic standard errors and Wald Z-tests for the covariance parameter estimates.<br />

DATA=<strong>SAS</strong>-data-set<br />

names the <strong>SAS</strong> data set to be used by PROC <strong>MIXED</strong>. <strong>The</strong> default is the most recently created<br />

data set.<br />

DFBW<br />

has the same effect as the DDFM=BW option in the MODEL statement.<br />

EMPIRICAL<br />

computes the estimated variance-covariance matrix of the fixed-effects parameters by using<br />

the asymptotically consistent estimator described in Huber (1967), White (1980), Liang and<br />

Zeger (1986), and Diggle, Liang, and Zeger (1994). This estimator is commonly referred to as<br />

the “sandwich” estimator, and it is computed as follows:<br />

IC<br />

.X 0bV 1 X/<br />

SX<br />

iD1<br />

X 0 i cVi 1 bi bi 0cVi 1 Xi<br />

!<br />

.X 0bV 1 X/<br />

Here, bi D yi Xi bˇ, S is the number of subjects, and matrices with an i subscript are<br />

those for the ith subject. You must include the SUBJECT= option in either a RANDOM or<br />

REPEATED statement for this option to take effect.<br />

When you specify the EMPIRICAL option, PROC <strong>MIXED</strong> adjusts all standard errors and test<br />

statistics involving the fixed-effects parameters. This changes output in the following tables<br />

(listed in Table 56.22): Contrast, CorrB, CovB, Diffs, Estimates, InvCovB, LSMeans, Slices,<br />

SolutionF, Tests1–Tests3. <strong>The</strong> OUTP= and OUTPM= data sets are also affected. Finally, the<br />

Satterthwaite and Kenward-Roger degrees of freedom methods are not available if you specify<br />

the EMPIRICAL option.<br />

displays a table of various information criteria. <strong>The</strong> criteria are all in smaller-is-better form,<br />

and are described in Table 56.3.<br />

Table 56.3 Information Criteria<br />

Criterion Formula Reference<br />

AIC 2` C 2d Akaike (1974)<br />

AICC 2` C 2dn =.n d 1/ Hurvich and Tsai (1989)<br />

Burnham and Anderson (1998)<br />

HQIC 2` C 2d log log n Hannan and Quinn (1979)<br />

BIC 2` C d log n Schwarz (1978)<br />

CAIC 2` C d.log n C 1/ Bozdogan (1987)

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