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High-Yield Neuroanatomy 5e

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18 Chapter 3<br />

Sensory (receptor) neurons<br />

Motor neuron<br />

Olfactory<br />

Auditory<br />

Cutaneous<br />

Dendrites<br />

Dendritic zone<br />

Axon hillock<br />

Initial segment<br />

Node<br />

of Ranvier<br />

Myelin sheath<br />

Axon<br />

Axon collaterals<br />

Schwann cell<br />

Telaxon<br />

Synaptic endings (terminal boutons)<br />

Neuromuscular junction<br />

Figure 3-1 Types of nerve cells. Olfactory neurons are bipolar and unmyelinated. Auditory neurons are bipolar and<br />

myelinated. Spinal (posterior root) ganglion cells (cutaneous) are pseudounipolar and myelinated. Motor neurons are<br />

multipolar and myelinated. Arrows indicate input through the axons of other neurons. (Modified from Carpenter MB,<br />

Sutin J. Human <strong>Neuroanatomy</strong>. Baltimore, MD: Williams & Wilkins; 1983:92, with permission.)<br />

B. Slow Anterograde Transport—responsible for transporting fibrillar cytoskeletal and protoplasmic<br />

elements. This process occurs at the rate of 1 to 5 mm/day.<br />

C. Fast Retrograde Transport—returns used materials from the axon terminal to the cell body<br />

for degradation and recycling at a rate of 100 to 200 mm/day. It transports nerve growth factor,<br />

neurotropic viruses, and toxins, such as herpes simplex, rabies, poliovirus, and tetanus toxin. It<br />

is mediated by neurotubules and dynein.<br />

IV<br />

Anterograde (Wallerian) Degeneration—characterized by the<br />

disappearance of axons and myelin sheaths and the secondary proliferation of Schwann cells. It<br />

occurs in the central nervous system (CNS) and the peripheral nervous system (PNS).<br />

V<br />

Chromatolysis—the result of retrograde degeneration in the neurons of the CNS and<br />

PNS. There is a loss of Nissl substance after axotomy.<br />

VI<br />

Regeneration of Nerve Cells

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