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Time: Tuesday, October 20, <strong>2009</strong>, 8:00 am - 12:00 noon<br />
Program#/Poster#: 555.4/AA32<br />
Topic: D.01.d. Olfaction: Central circuits <strong>an</strong>d neurotr<strong>an</strong>smitters<br />
Support: NSERC<br />
OGS<br />
University of Ottawa<br />
Title: Elucidating <strong>the</strong> neural circuitry involved with sex pheromones signaling in male goldfish<br />
Authors: *W. E. LADO 1 , D. C. SPANSWICK 2 , J. E. LEWIS 1 , V. L. TRUDEAU 1 ;<br />
1 2<br />
Biol., Univ. of Ottawa, Ottawa, ON, C<strong>an</strong>ada; Warwick Med. Sch., Univ. of Warwick,<br />
COVENTRY, United Kingdom<br />
Abstract: The sex pheromones, 17 αλπηα, 20 βετα-dihydroxy-4-pregene-3-one <strong>an</strong>d<br />
prostagl<strong>an</strong>din-F2αλπηα, elicit specific reproductive behaviours in male goldfish. To better<br />
underst<strong>an</strong>d <strong>the</strong> neural circuitry involved with sex pheromones signalling in goldfish<br />
reproduction, we used male goldfish brain expl<strong>an</strong>ts. The adv<strong>an</strong>tage of working with <strong>the</strong> expl<strong>an</strong>ts<br />
is that <strong>the</strong> neural circuitry <strong>from</strong> <strong>the</strong> olfactory bulb (OB) to <strong>the</strong> preoptic area (POA) is preserved.<br />
We electrically stimulated <strong>the</strong> OB <strong>an</strong>d per<strong>for</strong>med whole-cell current clamp recordings <strong>from</strong><br />
neurons in <strong>the</strong> POA to discern <strong>the</strong> functional properties <strong>an</strong>d connections of this circuitry. These<br />
neurons fired action potentials spont<strong>an</strong>eously with some also displaying burst firing. We<br />
demonstrate evidence <strong>for</strong> a monosynaptic connection between <strong>the</strong> OB <strong>an</strong>d POA implying a role<br />
<strong>for</strong> sex pheromones signal tr<strong>an</strong>smission through <strong>the</strong> medial olfactory tract. A major component<br />
of <strong>the</strong> synaptic connection was blocked by DL-2-amino-5-phosphonopent<strong>an</strong>oic acid (AP5), <strong>an</strong><br />
N-Methyl-D-Aspartate (NMDA) receptor <strong>an</strong>tagonist. 6-cy<strong>an</strong>o-7-nitroquinoxaline-2, 3-dione<br />
(CNQX), a non NMDA receptor <strong>an</strong>tagonist, subsequently blocked <strong>the</strong> rest of <strong>the</strong> response.<br />
Overall, <strong>the</strong>se results indicate that <strong>the</strong> functional connection between <strong>the</strong> OB <strong>an</strong>d POA of male<br />
goldfish mediated by glutamatergic neurotr<strong>an</strong>smission is monosynaptic. This is consistent with<br />
<strong>the</strong> major role glutamate plays in <strong>the</strong> hormonal regulation of reproduction in male goldfish.<br />
Disclosures: W.E. Lado, None; D.C. Sp<strong>an</strong>swick, None; J.E. Lewis, None; V.L. Trudeau,<br />
None.<br />
Poster<br />
555. Olfactory Bulb: Synapses <strong>an</strong>d Circuits<br />
Location: South Hall A
Time: Tuesday, October 20, <strong>2009</strong>, 8:00 am - 12:00 noon Program#/Poster#: 555.4/AA32 Topic: D.01.d. Olfaction: Central circuits <strong>an</strong>d neurotr<strong>an</strong>smitters Support: NSERC OGS University of Ottawa Title: Elucidating <strong>the</strong> neural circuitry involved with sex pheromones signaling in male goldfish Authors: *W. E. LADO 1 , D. C. SPANSWICK 2 , J. E. LEWIS 1 , V. L. TRUDEAU 1 ; 1 2 Biol., Univ. of Ottawa, Ottawa, ON, C<strong>an</strong>ada; Warwick Med. Sch., Univ. of Warwick, COVENTRY, United Kingdom Abstract: The sex pheromones, 17 αλπηα, 20 βετα-dihydroxy-4-pregene-3-one <strong>an</strong>d prostagl<strong>an</strong>din-F2αλπηα, elicit specific reproductive behaviours in male goldfish. To better underst<strong>an</strong>d <strong>the</strong> neural circuitry involved with sex pheromones signalling in goldfish reproduction, we used male goldfish brain expl<strong>an</strong>ts. The adv<strong>an</strong>tage of working with <strong>the</strong> expl<strong>an</strong>ts is that <strong>the</strong> neural circuitry <strong>from</strong> <strong>the</strong> olfactory bulb (OB) to <strong>the</strong> preoptic area (POA) is preserved. We electrically stimulated <strong>the</strong> OB <strong>an</strong>d per<strong>for</strong>med whole-cell current clamp recordings <strong>from</strong> neurons in <strong>the</strong> POA to discern <strong>the</strong> functional properties <strong>an</strong>d connections of this circuitry. These neurons fired action potentials spont<strong>an</strong>eously with some also displaying burst firing. We demonstrate evidence <strong>for</strong> a monosynaptic connection between <strong>the</strong> OB <strong>an</strong>d POA implying a role <strong>for</strong> sex pheromones signal tr<strong>an</strong>smission through <strong>the</strong> medial olfactory tract. A major component of <strong>the</strong> synaptic connection was blocked by DL-2-amino-5-phosphonopent<strong>an</strong>oic acid (AP5), <strong>an</strong> N-Methyl-D-Aspartate (NMDA) receptor <strong>an</strong>tagonist. 6-cy<strong>an</strong>o-7-nitroquinoxaline-2, 3-dione (CNQX), a non NMDA receptor <strong>an</strong>tagonist, subsequently blocked <strong>the</strong> rest of <strong>the</strong> response. Overall, <strong>the</strong>se results indicate that <strong>the</strong> functional connection between <strong>the</strong> OB <strong>an</strong>d POA of male goldfish mediated by glutamatergic neurotr<strong>an</strong>smission is monosynaptic. This is consistent with <strong>the</strong> major role glutamate plays in <strong>the</strong> hormonal regulation of reproduction in male goldfish. Disclosures: W.E. Lado, None; D.C. Sp<strong>an</strong>swick, None; J.E. Lewis, None; V.L. Trudeau, None. Poster 555. Olfactory Bulb: Synapses <strong>an</strong>d Circuits Location: South Hall A
Time: Tuesday, October 20, <strong>2009</strong>, 8:00 am - 12:00 noon Program#/Poster#: 555.5/AA33 Topic: D.01.d. Olfaction: Central circuits <strong>an</strong>d neurotr<strong>an</strong>smitters Support: NIH Gr<strong>an</strong>t 1F30DC010323-01 NIH Gr<strong>an</strong>t RO1 DC000566 Title: Adrenergic receptor-mediated disinhibition of olfactory bulb mitral cells triggers longterm enh<strong>an</strong>cement of gamma oscillations Authors: *S. PANDIPATI 1 , D. H. GIRE 2 , N. E. SCHOPPA 2 ; 1 MSTP, 2 Physiol. & Biophysics, Univ. Colorado Denver - AMC, Aurora, CO Abstract: Norepinephrine (NE) may be essential <strong>for</strong> m<strong>an</strong>y <strong>for</strong>ms of olfactory learning but <strong>the</strong> underlying cellular mech<strong>an</strong>isms are not known. One potential mech<strong>an</strong>ism was revealed by a recent study (Gire <strong>an</strong>d Schoppa, 2008) that showed that tr<strong>an</strong>sient exposure of olfactory bulb (OB) slices to NE could elicit long-term enh<strong>an</strong>cement of gamma oscillations (30-70 Hz) in <strong>the</strong> local field potential (LFP) evoked by olfactory nerve stimulation. Increased gamma oscillations are linked with olfactory learning (Martin et al., 2004). Here we studied acute actions of NE that may be responsible <strong>for</strong> NE’s long-term effects using patch-clamp recordings in slices <strong>from</strong> rat OB. Initial studies were done in young pups (P9-13). One prominent acute effect of NE was disinhibition of mitral cells, seen as a 51±7% reduction (n=8, p=0.0023) in <strong>the</strong> amplitude of inhibitory postsynaptic currents (IPSCs) evoked by electrical stimulation in <strong>the</strong> gr<strong>an</strong>ule cell layer (50-200 µA, 100 µsec). This effect appeared to be mediated mainly by alpha2-adrenergic receptors (ARs), as 5µM clonidine also reduced IPSCs (by 31±13%, n=8, p=0.04). Disinhibition is a plausible mech<strong>an</strong>ism <strong>for</strong> long-term enh<strong>an</strong>cement of gamma oscillations, since it could lead to elevated intracellular calcium typically associated with long-term synaptic ch<strong>an</strong>ges. Consistent with disinhibition triggering enh<strong>an</strong>ced gamma oscillations, we found that tr<strong>an</strong>sient exposure of slices to a moderate concentration of gabazine (5µM), to directly block GABAA receptors, mimicked NE’s action in inducing long-term enh<strong>an</strong>cement of gamma LFP oscillations in <strong>the</strong> external plexi<strong>for</strong>m layer (128±37% increase in gamma power, measured 50-60 min following washout of gabazine, n=4, p=0.041; gabazine co-applied with 12.5µM NMDA). Also, activation of alpha2-ARs alone with clonidine was sufficient to induce long-term enh<strong>an</strong>cement of <strong>the</strong> oscillations (83±22% increase, n=15, p=0.001). We also examined <strong>the</strong> age-dependence of NE’s effects on OB circuit properties. Whereas NE effectively induced long-term enh<strong>an</strong>cement of gamma oscillations in young rat pups, NE was ineffective at doing so in older pups (P18-19; 25±21% decrease, n=5, p=0.25). The difference in NE’s long-term effects with age may be linked to NE’s acute effects on gr<strong>an</strong>ule-to-mitral cell inhibition. While NE induced disinhibition in young pups, NE (20 µM) increased inhibition in older pups, as measured by <strong>the</strong> frequency of spont<strong>an</strong>eous IPSCs in mitral cells (174±39% increase, n=4, p=0.021; see also Nai et al., <strong>2009</strong>). These results suggest that NE-mediated disinhibition leading to enh<strong>an</strong>ced gamma oscillations might only occur in a limited age-window in rat pups.
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specification. Supported by the NIH
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Poster 505. Cell Lineage and Cell F
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Location: South Hall A Time: Tuesda
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mammalian Suppressor of Hairless (R
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Abstract: In spite of the considera
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Abstract: The dorsal root ganglia (
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Genome Canada Title: Pannexin 2, a
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Authors: *T. ROITBAK, L. A. CUNNING
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never express mature neuronal genes
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NIH Neuroscience Blueprint Title: A
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1 Dept. of Anatomy, Ajou Univ. Sch.
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Poster 506. Neurogenesis II Locatio
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from ND7 cells, showed an increase
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functions of the NZF/MyTgene family
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NIH T32 MH018268-24 Solnit Integrat
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pathway and its transient transloca
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(82±12%) in the number of GABAergi
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constructs were tagged with or coin
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Title: How do GFAP-expressing neura
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Disclosures: A. Pignatelli, None; J
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Location: South Hall A Time: Tuesda
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Disclosures: J.H. Lim, None; S.D. M
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Poster 507. Stem Cells: Basic Biolo
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significant changes in gene express
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embryonic period of rat corticogene
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PRIN 2005 Title: Death resistant ne
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Topic: A.03.b. Stem cells: Basic bi
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during development as well as betwe
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fate of MAPCs within the CNS is not
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Torsten and Ragnar Söderberg’s F
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Support: FNRS - Belgium Title: Prob
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Inserm Osteoarticular research gran
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animals (p
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Abstract: Currently there are no ef
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Time: Tuesday, October 20, 2009, 8:
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Poster 508. Development and Organiz
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Poster 508. Development and Organiz
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Disclosures: M. Nebieridze , None;
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Disclosures: Y. Kim, None; R. Sincl
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Disclosures: A. Haessly, None; B. S
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the connection at the level of the
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due to a per- or post-synaptic func
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suggest that ambient temperature ma
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509. Molecular Mechanisms Regulatin
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stationary neurons, the migration s
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Ser473 and Thr308 in the null cereb
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maintained in culture in medium sup
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development, may alter the proper m
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Program#/Poster#: 510.2/B35 Topic:
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Poster 510. Regeneration: PNS Locat
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Disclosures: D. Wu , None; A. Raafa
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Disclosures: R.M. Grumbles, None; C
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ody response, but interfered with a
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properties of sensory nerve grafts.
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510. Regeneration: PNS Location: So
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domains that are known to promote c
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Support: CIHR AHFMR Title: Side-to-
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Disclosures: X. Jing, None; T. Wang
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development and has been implicated
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Abstract: Peripheral nerve gaps tha
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Program#/Poster#: 510.23/B56 Topic:
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Poster 510. Regeneration: PNS Locat
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promote the elongation of intact ne
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examined the consequences on axonal
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using co-immunoprecipitation and di
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Abstract: A hallmark feature of NMD
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not by AMPA stimulation. Importantl
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phosphorylation site. We have gener
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damage has been reported to be a co
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have not been found previously in c
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Abstract: In the barrel cortex, fee
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Authors: *H. MAEJIMA 1 , S. SAKANO
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Poster 511. Glutamate Receptors: Ge
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Time: Tuesday, October 20, 2009, 8:
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indicating the presence of the two
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significance of the structure of Gl
- Page 155 and 156:
elicited by kainate and glutamate,
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the GluRdelta2 receptor in the lurc
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mediated inhibition, generated by s
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Time: Tuesday, October 20, 2009, 8:
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Poster 513. GABA-A Receptors: Physi
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As etomidate concentrations increas
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Authors: *J. ADAMS, T. G. SMART; Ne
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Poster 513. GABA-A Receptors: Physi
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Topic: B.02.o. GABA(A) receptors: P
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Master scholarship CONACyT Title: M
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Location: South Hall A Time: Tuesda
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these cells. α3KO mice showed an e
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Authors: *M. L. MCCRACKEN 1 , L. M.
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514. Glycine Receptors Location: So
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Poster 514. Glycine Receptors Locat
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glycine induced chloride currents.
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Authors: F. WELTZIEN 1 , I. PAARMAN
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Program#/Poster#: 514.10/B117 Topic
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occurs by interaction with splicing
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Disclosures: Y. Kim, None; L.O. Tru
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forebrain regions and that the α2
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Abstract: The postnatal development
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Program#/Poster#: 515.1/C1 Topic: B
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Disclosures: C. Tai, None; B.A. Mac
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this is indicative of changes in tw
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NISWENDER 1 , C. D. WEAVER 3 , C. W
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Program#/Poster#: 515.8/C8 Topic: B
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Poster 515. Muscarinic Receptors Lo
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515. Muscarinic Receptors Location:
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(OxoM) was significantly greater in
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phosphorylation, microdialysis and
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516. Serotonin Receptors II Locatio
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5-HT1A signaling pathways and mecha
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produced a similar phenotype to tra
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1 2 Dept Woman Child Hlth., Karolin
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Poster 516. Serotonin Receptors II
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to be formed in order to allow Gi/o
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TPH1 & 2 knockout mice. Another imp
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several behaviors in rodents report
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NIH Grant DA025412 ACADIA Pharmaceu
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Poster 516. Serotonin Receptors II
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pattern congaing). Results were the
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Abstract: Serotonin receptors in pr
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Topic: B.04.a. Sodium channels: Phy
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persistent sodium current is engage
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Authors: J.-H. WANG 1 , *N. CHEN 2
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Given the fact that the AIS of moto
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517. Sodium Channels: Physiology II
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hyperpolarized resting membrane pot
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with longer pulses. Macroscopic ina
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Support: Brain Research Trust Medic
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Location: South Hall A Time: Tuesda
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Poster 517. Sodium Channels: Physio
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channels activity at 2 mM Ca 2+ rev
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Title: The effect of 1-octanol on s
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NIH Grant 1F31NS059190 NIH Grant T3
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change alters CaV3.2 gating and act
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secondary dendrites. Ratiometric im
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Program#/Poster#: 518.10/C64 Topic:
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AA016852 AA017048 Title: Acute effe
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tools capable of distinguishing amo
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the most common mechanisms of chann
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Program#/Poster#: 519.3/C72 Topic:
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Title: Neurofibromin, CRMP-2 and pr
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Poster 519. Voltage-Dependent Calci
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IHCs or OHCs but may rather be caus
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Abstract: Voltage-gated calcium (Ca
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Support: NS029967 Title: Isoform-sp
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Time: Tuesday, October 20, 2009, 8:
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cells. The most prominent RIM1 effe
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messengers. One is the chemically m
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Abstract: A dominant form of presyn
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CONACyT Title: Gating charges per c
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US-Israel Binational Sci Fnd #20053
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Disclosures: P.M. Paez, None; D.J.
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variants. Therefore, the alternativ
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the prediction is that a BK-like cu
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Abstract: Modulation of ion channel
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Authors: *E. PETROFF; Biol. and Mol
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DNASTAR, Inc Title: Differential tr
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520. Calcium-Activated Potassium Ch
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of SK channels and had little effec
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pathway, consisting of axons from l
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Title: Loss of dendritic Ih results
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Poster 521. Ion Channels and Diseas
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causes pure familial hemiplegic mig
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may involve spontaneously occuring
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Abstract: Mutations in voltage-gate
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Time: Tuesday, October 20, 2009, 8:
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facilitate efflux at a distance fro
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Abstract: Voltage gated calcium cha
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that this channel regulates the mor
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Time: Tuesday, October 20, 2009, 8:
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521. Ion Channels and Disease Locat
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These results indicate that neurona
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ise to a reduced number of Kv1.1 su
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Title: Cholesterol elevation impair
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Poster 521. Ion Channels and Diseas
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alterations in ion channel expressi
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Abstract: Over the past 5 years an
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Abstract: Glial-derived primary bra
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Location: South Hall A Time: Tuesda
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fluorescent sensor that responds to
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adjacent synapses and were subseque
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Title: Photodamaging the ribbon dis
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Program#/Poster#: 522.9/E34 Topic:
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assembly, creating an energetic bar
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dependent fusion of a SV. We optica
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type of exocytotic vesicle and cell
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Support: NIH Grant GM081809 NIH Gra
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522. Neurtransmitter Release: Docki
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labeling showed extensive co-locali
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protein which is also implicated in
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NINDS UO1-NS058213 NIDA P50DA005274
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523. Modulation: Mechanisms of Acti
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Poster 523. Modulation: Mechanisms
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effect of the secondly applied drug
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Abstract: Transient, non-catastroph
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Time: Tuesday, October 20, 2009, 8:
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523. Modulation: Mechanisms of Acti
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sites, as it decreased the amplitud
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Abstract: NMDA receptors are critic
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Support: AHAF NIH Grant NS055804 Ti
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524. LTP: Physiology and Behavior I
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Moreover, the expression of some fo
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mg/kg/day) or saline during 3 days
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control levels in the presence of p
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the novel object recognition task,
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524. LTP: Physiology and Behavior I
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stimulation of the contralateral CA
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effects on cognitive functions, par
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escaling and convergence to a commo
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Abstract: We demonstrate here for t
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Time: Tuesday, October 20, 2009, 8:
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input resistance (RN = 108.24 ± 20
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nerve conduction block phenomenon,
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Authors: *K. M. CRISP; St Olaf Col.
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correlations and defined electrical
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Authors: T. F. BECKHAUSER 1 , C. V.
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Topic: C.02.n. Animal and experimen
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Program#/Poster#: 526.4/G27 Topic:
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different ages. Authors thank Dr. C
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Abstract: The cholinergic neurotran
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Topic: C.02.n. Animal and experimen
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Support: Alzheimer's Association AP
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Time: Tuesday, October 20, 2009, 8:
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2. Doraiswamy, P.M., et al. J Geron
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excess of Aβ in the brain. We have
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Authors: *S. M. KRANTIC 1 , W. YU 2
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Disclosures: M. Lange, None; R. Sow
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Poster 526. Alzheimer's Disease: Ex
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sham and lesion groups were able to
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e phagocytically compromised during
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Alzheimer's Association IIRG-02-375
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Disclosures: C. Perez Cruz, Abbott,
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necessarily precede one to another.
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Title: γ-Secretase activity altera
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were elevated by treatment with the
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effects in the brain without any me
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Univ. of Maryland, College Park, MD
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membrane synthesis. For instance, d
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Program#/Poster#: 527.13/H26 Topic:
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Program#/Poster#: 527.15/H28 Topic:
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clarify its distribution in human t
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Topic: C.02.d. Beta and gamma secre
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Location: South Hall A Time: Tuesda
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Collectively, these findings, taken
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consolidated memories (remembering)
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plaque and tangle model (Bi-TAPP) w
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Location: South Hall A Time: Tuesda
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pattern reminiscent of our previous
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Authors: *N. W. SEEDS 1 , S. FABBRO
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Time: Tuesday, October 20, 2009, 8:
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learning performance in the Morris
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immunoprecipitation/Western blottin
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Authors: *L. F. YAMASHITA, A. A. BO
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AG10688 Title: Neuronal colocalizat
- Page 509 and 510:
Disclosures: M.A. King, None; M.L.
- Page 511 and 512:
in the compromised cerebral vascula
- Page 513 and 514:
cognition has come from transgenic
- Page 515 and 516:
Support: NIH Grant RO1 AG20159 Titl
- Page 517 and 518:
Location: South Hall A Time: Tuesda
- Page 519 and 520:
were down-regulated. In contrast, g
- Page 521 and 522:
Title: Nicotine treatment of mild c
- Page 523 and 524:
oth AD Tg mice and young adult/aged
- Page 525 and 526:
Poster 529. Treatments: Alzheimer's
- Page 527 and 528:
excised 30 minutes and 3 hours afte
- Page 529 and 530:
Authors: *C. HOLSCHER 1 , V. A. GAU
- Page 531 and 532:
Poster 529. Treatments: Alzheimer's
- Page 533 and 534:
inhibit the protective action of AP
- Page 535 and 536:
of connectivity among neurons resul
- Page 537 and 538:
Title: Addressing the challenge of
- Page 539 and 540:
Poster 529. Treatments: Alzheimer's
- Page 541 and 542:
Location: South Hall A Time: Tuesda
- Page 543 and 544:
Disclosures: L.J. Street, None; S.
- Page 545 and 546:
significantly. When the nitrites le
- Page 547 and 548:
absence of vision. The present stud
- Page 549 and 550:
Title: PIB binding in Parkinson dis
- Page 551 and 552:
Location: South Hall A Time: Tuesda
- Page 553 and 554:
cortex, pre-supplementary motor are
- Page 555 and 556:
aetiology of VH in PD is unknown .H
- Page 557 and 558:
Employment (full or part-time); U.
- Page 559 and 560:
neurons. These results suggest that
- Page 561 and 562:
long-term levodopa therapy. It has
- Page 563 and 564:
Time: Tuesday, October 20, 2009, 8:
- Page 565 and 566:
a 6 h period by a neurologist blind
- Page 567 and 568:
Program#/Poster#: 530.19/J29 Topic:
- Page 569 and 570:
eductions, respectively, in LID to
- Page 571 and 572:
Authors: *E. L. PRANSKI, N. V. DALA
- Page 573 and 574:
530. Parkinson's Disease: Human Rel
- Page 575 and 576:
console, CE was measured into 5 con
- Page 577 and 578:
Support: NIH Grant 5T32GM007507 NIH
- Page 579 and 580:
deficiency leads specifically to ta
- Page 581 and 582:
months of age, with no differences
- Page 583 and 584:
Title: Dietary selenium deficiency
- Page 585 and 586:
Time: Tuesday, October 20, 2009, 8:
- Page 587 and 588:
have greater autoreceptor inhibitio
- Page 589 and 590:
DFG Transregio SFB TR3 A11 and D12
- Page 591 and 592:
poorly ubiquitinated when compared
- Page 593 and 594:
using the “tet-off” system. Whe
- Page 595 and 596:
Topic: C.03.d. Transgenic and relat
- Page 597 and 598:
531. Parkinson's Disease: Models II
- Page 599 and 600:
Poster 531. Parkinson's Disease: Mo
- Page 601 and 602:
Disclosures: M. Herzig, None; P. Sc
- Page 603 and 604:
oxygen species in neurons is preven
- Page 605 and 606:
Perugia, Perugia, Italy; 4 Ctr. of
- Page 607 and 608:
Topic: C.03.f. Mechanisms and degen
- Page 609 and 610:
Time: Tuesday, October 20, 2009, 8:
- Page 611 and 612:
Poster 532. Parkinson's Disease: Ra
- Page 613 and 614:
(100µg/50µl) or cyRADfV (negative
- Page 615 and 616:
Abstract: The inferior colliculus (
- Page 617 and 618:
Program#/Poster#: 532.14/L2 Topic:
- Page 619 and 620:
Disclosures: K.B. Dupre, None; K.L.
- Page 621 and 622:
loss of DA neurons 10 months after
- Page 623 and 624:
enhancer synphillin. We are current
- Page 625 and 626:
Grad. Sch. of Science, Kyoto Univ.,
- Page 627 and 628:
Time: Tuesday, October 20, 2009, 8:
- Page 629 and 630:
Location: South Hall A Time: Tuesda
- Page 631 and 632:
transiently reversed in DA-depleted
- Page 633 and 634:
and by Filter-trap assays and FCS (
- Page 635 and 636:
members of the Bcl-2 family. In add
- Page 637 and 638:
Biomedicine and Dept. of Biochem.,
- Page 639 and 640:
Title: Pathogenic mechanism and sma
- Page 641 and 642:
Abstract: Huntington’s disease (H
- Page 643 and 644:
Authors: *M. SHIMOJO; Univ. Kentuck
- Page 645 and 646:
Program#/Poster#: 533.13/L28 Topic:
- Page 647 and 648:
Poster 533. Huntington's Disease an
- Page 649 and 650:
iochemical properties. To further v
- Page 651 and 652:
aberrant chromatin remodeling is a
- Page 653 and 654:
oligomeric or protofibrillar forms
- Page 655 and 656:
neurodegeneration in the striatum a
- Page 657 and 658:
study of HD is how this polyQ-expan
- Page 659 and 660:
Title: Androgen receptor antagonist
- Page 661 and 662:
Program#/Poster#: 533.28/M5 Topic:
- Page 663 and 664:
Disclosures: R. Schneider, None; A.
- Page 665 and 666:
Disclosures: S.J. Bissel, None; G.
- Page 667 and 668:
duodenal epithelium to the blood st
- Page 669 and 670:
Authors: *D. GRIS 1 , Z. YE 1 , H.
- Page 671 and 672:
1 2 3 Physiol., Univ. of Toronto, T
- Page 673 and 674:
Pioneer Fund Title: Induction of au
- Page 675 and 676:
Disclosures: B.A. Faucheux, None; J
- Page 677 and 678:
mTOR activation. Since STI1 has imp
- Page 679 and 680:
Authors: *A. BACHIS 1 , V. AVDOSHIN
- Page 681 and 682:
Authors: *S. G. KOHAMA 1 , S. G. KR
- Page 683 and 684:
Poster 535. Aging of the Nervous Sy
- Page 685 and 686:
Abstract: Oxidative stress is assoc
- Page 687 and 688:
Poster 535. Aging of the Nervous Sy
- Page 689 and 690:
Program#/Poster#: 535.8/M30 Topic:
- Page 691 and 692:
Title: 13C isotopic incorporation s
- Page 693 and 694:
Poster 535. Aging of the Nervous Sy
- Page 695 and 696:
patent or other intellectual proper
- Page 697 and 698:
Abstract: The serotonergic system i
- Page 699 and 700:
Disclosures: M.C. Mitschelen, None;
- Page 701 and 702:
ml water/day. Results: A multivaria
- Page 703 and 704:
Abstract: Neurodegenerative disorde
- Page 705 and 706:
Authors: *G. L. BECKER 1 , P. J. HU
- Page 707 and 708:
RESNICK 1 ; 1 Natl. Inst. On Aging/
- Page 709 and 710:
Disclosures: D.H. Salat, None; S.Y.
- Page 711 and 712:
Poster 535. Aging of the Nervous Sy
- Page 713 and 714:
Disclosures: B. Setlow, None; D.S.
- Page 715 and 716:
Disclosures: B. Levant, Friesland F
- Page 717 and 718:
Disclosures: K. Hashimoto-Torii, No
- Page 719 and 720:
Abstract: Methylphenidate (MPH) tre
- Page 721 and 722:
Location: South Hall A Time: Tuesda
- Page 723 and 724:
and examined the function of STRAD
- Page 725 and 726:
Fédération des Maladies Orpheline
- Page 727 and 728:
above are either absent or altered
- Page 729 and 730:
NSF predoctoral fellowship Title: L
- Page 731 and 732:
Topic: C.06.k. Animal models and me
- Page 733 and 734:
NARSAD, B. Research Grant (principa
- Page 735 and 736:
neuropathology in these human devel
- Page 737 and 738:
Abstract: Determining the timing of
- Page 739 and 740:
Topic: C.06.d. Developmental disord
- Page 741 and 742:
mTOR hyperactivity at the cellular
- Page 743 and 744:
Authors: *K. E. WATKINS 1 , N. A. B
- Page 745 and 746:
Program#/Poster#: 537.3/O3 Topic: C
- Page 747 and 748:
p=0.43) with converging values in t
- Page 749 and 750:
Topic: C.06.j. ADHD, SLI, dyslexia
- Page 751 and 752:
Dcdc2 in mice, behavioral features
- Page 753 and 754:
the role for this gene in the etiol
- Page 755 and 756:
Location: South Hall A Time: Tuesda
- Page 757 and 758:
examining functional-anatomic devel
- Page 759 and 760:
inhibit on 50% of stop-trials. Stop
- Page 761 and 762:
Support: Finnish Cultural Foundatio
- Page 763 and 764:
Poster 537. Developmental Disorders
- Page 765 and 766:
stimulus. In our fMRI design, prosa
- Page 767 and 768:
Killam scholarship NSERC scholarshi
- Page 769 and 770:
Topic: C.07.j. Animal models Suppor
- Page 771 and 772:
538. Epilepsy: Inflammation and Imm
- Page 773 and 774:
538. Epilepsy: Inflammation and Imm
- Page 775 and 776:
different brain regions. This study
- Page 777 and 778:
pilocarpine-induced SE leads to hip
- Page 779 and 780:
pilocarpine induces prolonged SE re
- Page 781 and 782:
NS051445-04 Title: Increased incide
- Page 783 and 784:
Poster 539. Epilepsy: Anticonvulsan
- Page 785 and 786:
(dentate gyrus subfield) hippocampu
- Page 787 and 788:
Authors: *T. M. WYCKHUYS 1 , P. BOO
- Page 789 and 790:
Poster 539. Epilepsy: Anticonvulsan
- Page 791 and 792:
Poster 539. Epilepsy: Anticonvulsan
- Page 793 and 794:
(saline, 0.2 mls, i.p.), LY379268 (
- Page 795 and 796:
Authors: *K. K. AKULA 1 , S. K. KUL
- Page 797 and 798:
Time: Tuesday, October 20, 2009, 8:
- Page 799 and 800:
ecto-ATPase inhibitor ARL 67156. In
- Page 801 and 802:
protected confirming the anticonvul
- Page 803 and 804:
NIH Grants R01NS048216 AHA Establis
- Page 805 and 806:
Time: Tuesday, October 20, 2009, 8:
- Page 807 and 808:
Poster 540. Ischemia: Glia Location
- Page 809 and 810:
dependent degradation of spectrin w
- Page 811 and 812:
Abstract: CD36, a multi-functional
- Page 813 and 814:
Title: Different mononuclear cell p
- Page 815 and 816:
Location: South Hall A Time: Tuesda
- Page 817 and 818:
Disclosures: C.C. Pegg, None; M.A.
- Page 819 and 820:
show that DHPG activates extracellu
- Page 821 and 822:
Abstract: Ethyl pyruvate (EP), a si
- Page 823 and 824:
Title: The relative roles of neuron
- Page 825 and 826:
Time: Tuesday, October 20, 2009, 8:
- Page 827 and 828:
2 Wilke et al., 2004, J Neuropathol
- Page 829 and 830:
attentional lapses, and depressed m
- Page 831 and 832:
Program#/Poster#: 541.1/R4 Topic: C
- Page 833 and 834:
performance, evolving white matter
- Page 835 and 836:
within these networks between healt
- Page 837 and 838:
Support: The Rockefeller University
- Page 839 and 840:
and ROI analyses revealed no areas
- Page 841 and 842:
Support: JIEDDO-001 Mid-Atlantic MI
- Page 843 and 844:
diminished overall capacity to inte
- Page 845 and 846:
DOD PT075675 Marshall Goldberg Fund
- Page 847 and 848:
Poster 542. Spinal Cord Injury: Fro
- Page 849 and 850:
indicate that acupuncture significa
- Page 851 and 852:
einnervate their distal targets. To
- Page 853 and 854:
Time: Tuesday, October 20, 2009, 8:
- Page 855 and 856:
Disclosures: S. Veiga, None; K. Irv
- Page 857 and 858:
Blood β-hydroxybutyrate levels of
- Page 859 and 860:
NIH Grant NS31193 New York State Co
- Page 861 and 862:
Poster 542. Spinal Cord Injury: Fro
- Page 863 and 864:
EMG, trains of motor unit potential
- Page 865 and 866:
the area of residual myelin in the
- Page 867 and 868:
upregulation of genes in the A-HX g
- Page 869 and 870:
carried out to confirm differences
- Page 871 and 872:
Program#/Poster#: 542.23/T2 Topic:
- Page 873 and 874:
of damage across spinal sections th
- Page 875 and 876:
physiologic characteristics they sh
- Page 877 and 878:
Location: South Hall A Time: Tuesda
- Page 879 and 880:
Poster 542. Spinal Cord Injury: Fro
- Page 881 and 882:
Disclosures: A. Jayaraman, None; J.
- Page 883 and 884:
plasticity, we also tested E2’s a
- Page 885 and 886:
Abstract: The 'Progesterone in Brai
- Page 887 and 888:
Topic: C.11.h. Neuroprotective mech
- Page 889 and 890:
543. Cell Death Mechanisms; Mitocho
- Page 891 and 892:
Disclosures: C.C. Aguirre, None; A.
- Page 893 and 894:
low doses (Ec50 less than 5nM), esp
- Page 895 and 896:
Abstract: We reported before that 1
- Page 897 and 898:
Authors: *K. D. YI, J. W. SIMPKINS;
- Page 899 and 900:
Authors: L. XIE, E. POTEET, W. LI,
- Page 901 and 902:
against cognitive decline and memor
- Page 903 and 904:
and mitochondrial function are esse
- Page 905 and 906:
Time: Tuesday, October 20, 2009, 8:
- Page 907 and 908:
vesicles, broken and disorganized c
- Page 909 and 910:
Abstract: Increasing evidence sugge
- Page 911 and 912:
Poster 544. Neurotoxicity: Toxins I
- Page 913 and 914:
ain after i.m. injection. The highl
- Page 915 and 916:
Support: FCT- Grant POCI/SAU-FCF/58
- Page 917 and 918:
Poster 544. Neurotoxicity: Toxins I
- Page 919 and 920:
Results revealed DAT complexes pres
- Page 921 and 922:
Title: D. melanogaster: A new model
- Page 923 and 924:
Support: NIH Grant P20 RR16454 USAM
- Page 925 and 926:
Support: Department of Chemistry WS
- Page 927 and 928:
Title: The striatal neurokinin-1 an
- Page 929 and 930:
visualized using fluorescent phallo
- Page 931 and 932:
Authors: *A. C. VALENCIA 1 , J. MOR
- Page 933 and 934:
Support: NIH/NIA/IRP FAPESP Brazil
- Page 935 and 936:
FONDECYT Grant 1090353 Title: Diffe
- Page 937 and 938:
Location: South Hall A Time: Tuesda
- Page 939 and 940:
endothelial interactions. This will
- Page 941 and 942:
of CD200 in immune-regulation and d
- Page 943 and 944:
temporal concentration increases of
- Page 945 and 946:
Alzheimer’s Association (KA) AG24
- Page 947 and 948:
Time: Tuesday, October 20, 2009, 8:
- Page 949 and 950:
Topic: C.11.m. Neuroinflammation: C
- Page 951 and 952:
Disclosures: R.F. Silva, None; S.L.
- Page 953 and 954:
vessels in the neonatal mouse brain
- Page 955 and 956:
death within 24 hours. This charact
- Page 957 and 958:
(bDC). These bDCs share a remarkabl
- Page 959 and 960:
proliferation. It is now evident th
- Page 961 and 962:
Abstract: Negative symptoms (avolit
- Page 963 and 964:
546. Schizophrenia and Bi-polar Dis
- Page 965 and 966:
Poster 546. Schizophrenia and Bi-po
- Page 967 and 968:
Authors: *M. S. MILELLA, F. PASSARE
- Page 969 and 970:
546. Schizophrenia and Bi-polar Dis
- Page 971 and 972:
mice. EGR-1 protein levels were ele
- Page 973 and 974:
Abstract: α2 norepinephrine (NE) r
- Page 975 and 976:
psychotic symptoms with PPI impairm
- Page 977 and 978:
startle response were examined betw
- Page 979 and 980:
Topic: C.15.d. Animal models Suppor
- Page 981 and 982:
546. Schizophrenia and Bi-polar Dis
- Page 983 and 984:
antagonist MLA (0.1 mM; 0.5µL), si
- Page 985 and 986:
that these Nf1+/- RGC phenotypes re
- Page 987 and 988:
cell-cell integrity, DNA fragmentat
- Page 989 and 990:
found a significant decrease in pro
- Page 991 and 992:
subcellular localization during a c
- Page 993 and 994:
Authors: *D. BUCHMAN, J. ILLES; Med
- Page 995 and 996:
Poster 548. Mood Disorders: Human B
- Page 997 and 998:
Authors: *A. J. HOLMES 1 , R. BOGDA
- Page 999 and 1000:
Support: KAKENHI (20790841) Title:
- Page 1001 and 1002:
Program#/Poster#: 548.8/W26 Topic:
- Page 1003 and 1004:
Location: South Hall A Time: Tuesda
- Page 1005 and 1006:
together, this study demonstrates t
- Page 1007 and 1008:
depressed compared to nondepressed
- Page 1009 and 1010:
1 Dept of Biol. Res., Lundbeck Res.
- Page 1011 and 1012:
Disclosures: C.H. Duman, None; M. B
- Page 1013 and 1014:
egulatory effects including glucose
- Page 1015 and 1016:
Topic: C.16.f. Mood disorders: Expe
- Page 1017 and 1018:
Location: South Hall A Time: Tuesda
- Page 1019 and 1020:
Disclosures: U.C. Campbell, None; S
- Page 1021 and 1022:
eward-related effects of the TRI, D
- Page 1023 and 1024:
Authors: E. ZHANG 1 , R. C. C. CHAN
- Page 1025 and 1026:
Title: Neuroplastic changes associa
- Page 1027 and 1028:
Poster 549. Mood Disorders: Experim
- Page 1029 and 1030:
fluoxetine. No significant changes
- Page 1031 and 1032:
Title: Peripheral infusion of the p
- Page 1033 and 1034:
Abstract: In recent years it has be
- Page 1035 and 1036:
Topic: C.17.bb. Neural plasticity,
- Page 1037 and 1038:
increased AMPA/NMDA ratio with prol
- Page 1039 and 1040:
nucleus accumbens (NAc) and the ext
- Page 1041 and 1042:
Disclosures: B.A. Grueter, None; R.
- Page 1043 and 1044:
electrophysiological experiments sh
- Page 1045 and 1046:
IL; 3 Psychiatry, Yale Univ. Sch. o
- Page 1047 and 1048:
550. Neural Plasticity, Dependence,
- Page 1049 and 1050:
Disclosures: Z.R. Daruwalla, None;
- Page 1051 and 1052:
development or expression of behavi
- Page 1053 and 1054:
Fondation pour la Recherche Medical
- Page 1055 and 1056:
550. Neural Plasticity, Dependence,
- Page 1057 and 1058:
Poster 550. Neural Plasticity, Depe
- Page 1059 and 1060:
persistence of these neuroadaptatio
- Page 1061 and 1062:
Title: Toluene intoxication: Struct
- Page 1063 and 1064:
Program#/Poster#: 551.1/Y4 Topic: C
- Page 1065 and 1066:
highest dose of cocaine and ampheta
- Page 1067 and 1068:
they had access to either a single
- Page 1069 and 1070:
Abstract: Background: We have previ
- Page 1071 and 1072:
Location: South Hall A Time: Tuesda
- Page 1073 and 1074:
Poster 551. Behavioral Pharmacology
- Page 1075 and 1076:
each group), and the respective sur
- Page 1077 and 1078:
adolescence with amphetamine demons
- Page 1079 and 1080:
of CART mRNA levels in relation to
- Page 1081 and 1082:
locomotor stimulation at low to mod
- Page 1083 and 1084:
Abstract: It is well known that the
- Page 1085 and 1086:
552. Alcohol: Neural Mechanisms II
- Page 1087 and 1088:
Disclosures: Y. Chen, None; S.F. Le
- Page 1089 and 1090:
educed basal glutamate levels (appr
- Page 1091 and 1092:
Abstract: Poly-drug abuse may be pr
- Page 1093 and 1094:
Title: Ethanol increases GAPDH-TIEG
- Page 1095 and 1096:
Location: South Hall A Time: Tuesda
- Page 1097 and 1098:
expressing microglia (OX6) observed
- Page 1099 and 1100:
consumption by C57Bl/6J mice. The r
- Page 1101 and 1102:
Abstract: Ethanol may be consumed f
- Page 1103 and 1104:
Location: South Hall A Time: Tuesda
- Page 1105 and 1106:
Poster 552. Alcohol: Neural Mechani
- Page 1107 and 1108:
ain tissues of different treated gr
- Page 1109 and 1110:
Authors: I. G. BARBOSA LUNA, J. M.
- Page 1111 and 1112:
Topic: C.17.e. Alcohol: Neural mech
- Page 1113 and 1114:
553. Cocaine, Methylphenidate, and
- Page 1115 and 1116:
Poster 553. Cocaine, Methylphenidat
- Page 1117 and 1118:
period rats were trained to self-ad
- Page 1119 and 1120:
sodium butyrate injected immediatel
- Page 1121 and 1122:
non-responders spent the majority o
- Page 1123 and 1124:
Title: The effects of adrenalectomy
- Page 1125 and 1126: Program#/Poster#: 553.12/Z25 Topic:
- Page 1127 and 1128: NIH Grant R01 MH49469 NIH Grant F31
- Page 1129 and 1130: Disclosures: D.R. Ramirez, None; X.
- Page 1131 and 1132: at the basolateral amygdala (BLA).
- Page 1133 and 1134: Title: Sex differences in cocaine p
- Page 1135 and 1136: 553. Cocaine, Methylphenidate, and
- Page 1137 and 1138: Disclosures: M.T. McCoy, Department
- Page 1139 and 1140: Abstract: Manganese enhanced magnet
- Page 1141 and 1142: Disclosures: T.Z. Ramsoy, None; K.S
- Page 1143 and 1144: and removal of the 22 N-terminal am
- Page 1145 and 1146: methamphetamine induced more extens
- Page 1147 and 1148: Location: South Hall A Time: Tuesda
- Page 1149 and 1150: Disclosures: J. Nickell, None; A. V
- Page 1151 and 1152: Poster 554. Methamphetamine and Rel
- Page 1153 and 1154: Disclosures: K.A. Horner, None; Y.E
- Page 1155 and 1156: male and female CRF-R2 knockout (KO
- Page 1157 and 1158: Time: Tuesday, October 20, 2009, 8:
- Page 1159 and 1160: Location: South Hall A Time: Tuesda
- Page 1161 and 1162: The findings support the idea that
- Page 1163 and 1164: T32HL076133 Title: The acute effect
- Page 1165 and 1166: Abstract: Methamphetamine (METH) ab
- Page 1167 and 1168: Authors: *N. CAI, B. LADENHEIM, M.
- Page 1169 and 1170: Royal Gloden Jubilee PhD Program Ti
- Page 1171 and 1172: mediated by vasoactive eicosanoids.
- Page 1173 and 1174: Title: Dendrodendritic transmission
- Page 1175: Location: South Hall A Time: Tuesda
- Page 1179 and 1180: synapses between ET cells and GABAe
- Page 1181 and 1182: we demonstrate that the activation
- Page 1183 and 1184: had no consistent effect on mIPSCs
- Page 1185 and 1186: Authors: *N. KANG 1 , M. J. BAUM 2
- Page 1187 and 1188: NIH Grant DC006972 Title: The locat
- Page 1189 and 1190: Poster 555. Olfactory Bulb: Synapse
- Page 1191 and 1192: excitatory to inhibitory shift betw
- Page 1193 and 1194: ange of preferred AM frequencies de
- Page 1195 and 1196: Authors: *D. P. KNUDSEN 1 , T. Q. G
- Page 1197 and 1198: Title: Laminar dependent representa
- Page 1199 and 1200: Abstract: The auditory cortex is in
- Page 1201 and 1202: Time: Tuesday, October 20, 2009, 8:
- Page 1203 and 1204: and savannah forest scenes (60 seco
- Page 1205 and 1206: consonant discriminations can be pe
- Page 1207 and 1208: Authors: *N. HIGGINS 1 , D. A. STOR
- Page 1209 and 1210: Title: Local field potentials and s
- Page 1211 and 1212: Title: Neuronal response latency an
- Page 1213 and 1214: Time: Tuesday, October 20, 2009, 8:
- Page 1215 and 1216: Disclosures: J.M. Bouskila, None; M
- Page 1217 and 1218: favored the hypothesis that eCBs fu
- Page 1219 and 1220: 1 2 3 Devers Eye Inst., Portland, O
- Page 1221 and 1222: Title: Tropisetron as a neuroprotec
- Page 1223 and 1224: Location: South Hall A Time: Tuesda
- Page 1225 and 1226: premature ganglion cells. These res
- Page 1227 and 1228:
Tectal EP amplitudes did not signif
- Page 1229 and 1230:
esponses over time. The initial lig
- Page 1231 and 1232:
Location: South Hall A Time: Tuesda
- Page 1233 and 1234:
amplitude is set by a balance of Ca
- Page 1235 and 1236:
Kv4.2 was determined by immunohisto
- Page 1237 and 1238:
Disclosures: H. Kim, None; J. Lee,
- Page 1239 and 1240:
We have previously identified the c
- Page 1241 and 1242:
Depolarizing a ‘donor’ cone eli
- Page 1243 and 1244:
Title: The impact of temporal frequ
- Page 1245 and 1246:
Poster 558. Visual Motion: Neural M
- Page 1247 and 1248:
motion alone to that evoked by the
- Page 1249 and 1250:
Support: NIH Grant AG17596 NIH Gran
- Page 1251 and 1252:
Location: South Hall A Time: Tuesda
- Page 1253 and 1254:
Further, the central CCG peak was n
- Page 1255 and 1256:
Authors: *Y. GU 1 , G. C. DEANGELIS
- Page 1257 and 1258:
Poster 558. Visual Motion: Neural M
- Page 1259 and 1260:
velocity signals are processed thro
- Page 1261 and 1262:
model shows how vector decompositio
- Page 1263 and 1264:
and whole-cell recordings. Tectal n
- Page 1265 and 1266:
effector and object in a retinal fr
- Page 1267 and 1268:
motion axis (George et al, 2002). I
- Page 1269 and 1270:
Abstract: Motion aftereffects (MAE)
- Page 1271 and 1272:
Topic: D.06.e. Pursuit Support: MRC
- Page 1273 and 1274:
these changes in the symmetry of th
- Page 1275 and 1276:
Authors: *C. J. COLLINS, R. ACKERLE
- Page 1277 and 1278:
Poster 559. Pursuit Eye Movements L
- Page 1279 and 1280:
task. While fixating a stationary s
- Page 1281 and 1282:
559. Pursuit Eye Movements Location
- Page 1283 and 1284:
suggest that NOT serves as an impor
- Page 1285 and 1286:
eye position at the end of the sacc
- Page 1287 and 1288:
To explicitly test the causal contr
- Page 1289 and 1290:
Authors: *J. MARUTA 1 , M. SUH 2 ,
- Page 1291 and 1292:
Location: South Hall A Time: Tuesda
- Page 1293 and 1294:
administration of BPN (100 ng/kg/2x
- Page 1295 and 1296:
alter morphine-induced CPP and/or a
- Page 1297 and 1298:
Topic: D.08.bb. Opioids Support: NI
- Page 1299 and 1300:
greater than morphine. Of note, the
- Page 1301 and 1302:
the possible relevance of the arach
- Page 1303 and 1304:
560. Opioids: Mechanism of Action L
- Page 1305 and 1306:
Poster 560. Opioids: Mechanism of A
- Page 1307 and 1308:
560. Opioids: Mechanism of Action L
- Page 1309 and 1310:
with either MOR (1 µg), FEN (1 ng)
- Page 1311 and 1312:
Authors: A. DOGRUL 1 , *M. H. OSSIP
- Page 1313 and 1314:
sensitive enough to demonstrate agi
- Page 1315 and 1316:
Poster 560. Opioids: Mechanism of A
- Page 1317 and 1318:
injected with CFA in the masseter a
- Page 1319 and 1320:
Title: Effect of interleukin-8 rece
- Page 1321 and 1322:
Time: Tuesday, October 20, 2009, 8:
- Page 1323 and 1324:
Poster 561. Neuropathic Pain: Infla
- Page 1325 and 1326:
Clark AK, Yip PK, Grist J, Gentry C
- Page 1327 and 1328:
all 10 baseline images before lamin
- Page 1329 and 1330:
dorsal horn in models of pain creat
- Page 1331 and 1332:
Authors: P. FELDMAN 1 , H. JUNG 2 ,
- Page 1333 and 1334:
Time: Tuesday, October 20, 2009, 8:
- Page 1335 and 1336:
Topic: D.08.t. Mechanisms of neurop
- Page 1337 and 1338:
Poster 561. Neuropathic Pain: Infla
- Page 1339 and 1340:
Disclosures: T. Berta, None; Y. Liu
- Page 1341 and 1342:
Disclosures: O. Rosenthal, Unilever
- Page 1343 and 1344:
staircase procedure based on a two-
- Page 1345 and 1346:
Abstract: The brain needs to encode
- Page 1347 and 1348:
Program#/Poster#: 562.8/DD25 Topic:
- Page 1349 and 1350:
562. Tactile Stimulation and Proces
- Page 1351 and 1352:
Time: Tuesday, October 20, 2009, 8:
- Page 1353 and 1354:
Time: Tuesday, October 20, 2009, 8:
- Page 1355 and 1356:
compared to the evoked response to
- Page 1357 and 1358:
Authors: *S. YEO 1,2 , I.-H. CHOE 3
- Page 1359 and 1360:
Program#/Poster#: 562.19/DD36 Topic
- Page 1361 and 1362:
week 1, 36±38% after week 2, 55±3
- Page 1363 and 1364:
Morton Cure Paralysis Fund Title: A
- Page 1365 and 1366:
Topic: D.10.a. Plasticity Support:
- Page 1367 and 1368:
Program#/Poster#: 563.7/DD43 Topic:
- Page 1369 and 1370:
of hyperreflexia after SCI and open
- Page 1371 and 1372:
Authors: *E. M. ANDREWS 1,2 , Q. F.
- Page 1373 and 1374:
Location: South Hall A Time: Tuesda
- Page 1375 and 1376:
NeuN, calbindin (CB), neuron specif
- Page 1377 and 1378:
and Synapsin-I proteins. The functi
- Page 1379 and 1380:
well as in decerebrated cats by spi
- Page 1381 and 1382:
Support: Canadian Institute of Heal
- Page 1383 and 1384:
564. Rhythmic Movements: Afferent C
- Page 1385 and 1386:
organization forms a potent and dur
- Page 1387 and 1388:
antagonists to the rostral bath had
- Page 1389 and 1390:
Time: Tuesday, October 20, 2009, 8:
- Page 1391 and 1392:
sensillae (CS). Two types of reacti
- Page 1393 and 1394:
flexion signals from the tibia (Bä
- Page 1395 and 1396:
Topic: D.11.d. Afferent control Sup
- Page 1397 and 1398:
Poster 564. Rhythmic Movements: Aff
- Page 1399 and 1400:
p0.05). To assess the CabPK influen
- Page 1401 and 1402:
Program#/Poster#: 564.21/DD72 Topic
- Page 1403 and 1404:
Program#/Poster#: 565.2/DD74 Topic:
- Page 1405 and 1406:
in behavioral experiments with inta
- Page 1407 and 1408:
Abstract: A fundamental problem of
- Page 1409 and 1410:
Location: South Hall A Time: Tuesda
- Page 1411 and 1412:
Topic: D.11.b. Connectivity Support
- Page 1413 and 1414:
sustained activity pattern was corr
- Page 1415 and 1416:
examine the organization of the ves
- Page 1417 and 1418:
Support: CIHR 79416 Will-to-Win Sch
- Page 1419 and 1420:
Poster 565. Rhythmic Motor Networks
- Page 1421 and 1422:
document modulation of MIo neuron a
- Page 1423 and 1424:
abuse also trigger the release of t
- Page 1425 and 1426:
1 2 Behavioral Neurosci Br., NIDA,
- Page 1427 and 1428:
Location: South Hall A Time: Tuesda
- Page 1429 and 1430:
566. Basal Ganglia: Transmitters an
- Page 1431 and 1432:
dopaminergic cells in the posterior
- Page 1433 and 1434:
Program#/Poster#: 566.11/EE26 Topic
- Page 1435 and 1436:
Poster 566. Basal Ganglia: Transmit
- Page 1437 and 1438:
Disclosures: T. Lerner, None; A.C.
- Page 1439 and 1440:
Abstract: Cbln1 (precerebellin) is
- Page 1441 and 1442:
Authors: S. TAI, *L. LEUNG; Univ. W
- Page 1443 and 1444:
Topic: D.15.a. Transmitters and neu
- Page 1445 and 1446:
Location: South Hall A Time: Tuesda
- Page 1447 and 1448:
Poster 567. Basal Ganglia: Electrop
- Page 1449 and 1450:
external pallidum are known to exhi
- Page 1451 and 1452:
nature of synchronous beta oscillat
- Page 1453 and 1454:
Location: South Hall A Time: Tuesda
- Page 1455 and 1456:
smaller subset entrained to theta-b
- Page 1457 and 1458:
Abstract: We have previously traine
- Page 1459 and 1460:
Support: DA 06886 DA 04551 T32 Trai
- Page 1461 and 1462:
Location: South Hall A Time: Tuesda
- Page 1463 and 1464:
and movement, using a paradigm desi
- Page 1465 and 1466:
mechanism thought to prevent the br
- Page 1467 and 1468:
A brain area that has been closely
- Page 1469 and 1470:
Abstract: It is now widely believed
- Page 1471 and 1472:
Authors: E. BRAZHNIK, I. AVILA, N.
- Page 1473 and 1474:
Poster 567. Basal Ganglia: Electrop
- Page 1475 and 1476:
chronic stroke. The present data su
- Page 1477 and 1478:
controls its own load in maintainin
- Page 1479 and 1480:
Topic: D.17.d. Stroke, damage, or d
- Page 1481 and 1482:
task (0.11). There was a positive c
- Page 1483 and 1484:
Res. Inst., Kyoto Univ., Inuyama, J
- Page 1485 and 1486:
Poster 568. Stroke: Damage or Disea
- Page 1487 and 1488:
glial (myoinositol, mIn), and gluta
- Page 1489 and 1490:
Topic: D.17.d. Stroke, damage, or d
- Page 1491 and 1492:
Poster 568. Stroke: Damage or Disea
- Page 1493 and 1494:
Disclosures: S. Churchill, None; D.
- Page 1495 and 1496:
daily life. Although studies in hea
- Page 1497 and 1498:
Abstract: Many activities of daily
- Page 1499 and 1500:
Location: South Hall A Time: Tuesda
- Page 1501 and 1502:
These preliminary data suggests tha
- Page 1503 and 1504:
568. Stroke: Damage or Disease - Me
- Page 1505 and 1506:
Poster 568. Stroke: Damage or Disea
- Page 1507 and 1508:
final position. In contrast, the PO
- Page 1509 and 1510:
Recently, the relationship between
- Page 1511 and 1512:
Authors: E. CHANG 1 , *J. T. KING 2
- Page 1513 and 1514:
Title: Retinoic acid stimulates est
- Page 1515 and 1516:
Program#/Poster#: 569.7/EE98 Topic:
- Page 1517 and 1518:
Disclosures: B.W. Bakkum, None; L.
- Page 1519 and 1520:
specific to E2. In support, pharmac
- Page 1521 and 1522:
not (reproductively-senescent). We
- Page 1523 and 1524:
Topic: E.01.d. Steroids and plastic
- Page 1525 and 1526:
Interestingly, none of these estrog
- Page 1527 and 1528:
spatio-temporal subcellular distrib
- Page 1529 and 1530:
Title: Maternal care and perinatal
- Page 1531 and 1532:
Disclosures: K.M. Olesen, None; N.
- Page 1533 and 1534:
Intriguingly, the autonomic respons
- Page 1535 and 1536:
measured plasma norepinephrine (NE)
- Page 1537 and 1538:
Authors: E. T. GILBREATH 1 , J. L.
- Page 1539 and 1540:
Authors: *R. P. GAYKEMA, G. C. THAC
- Page 1541 and 1542:
Support: NSERC Canadian Foundation
- Page 1543 and 1544:
Location: South Hall A Time: Tuesda
- Page 1545 and 1546:
associated with differences in both
- Page 1547 and 1548:
571. Parental Behavior Location: So
- Page 1549 and 1550:
571. Parental Behavior Location: So
- Page 1551 and 1552:
attained had over 10 times the numb
- Page 1553 and 1554:
Time: Tuesday, October 20, 2009, 8:
- Page 1555 and 1556:
that this average round-the-clock m
- Page 1557 and 1558:
maternal experience. Our preliminar
- Page 1559 and 1560:
divergent paternal responses. P. ca
- Page 1561 and 1562:
castration reduces the amount of hu
- Page 1563 and 1564:
e related. In this study, sexually
- Page 1565 and 1566:
Authors: *K. M. SEIP 1 , J. I. MORR
- Page 1567 and 1568:
Authors: *D. POPA, E. BREEN, L. DUG
- Page 1569 and 1570:
Topic: E.04.b. Respiratory regulati
- Page 1571 and 1572:
Authors: N. R. NELSON 1 , *M. BEHAN
- Page 1573 and 1574:
eceptor antagonists AP-5 and/or CNQ
- Page 1575 and 1576:
Program#/Poster#: 572.9/FF14 Topic:
- Page 1577 and 1578:
Location: South Hall A Time: Tuesda
- Page 1579 and 1580:
Disclosures: A.T. Takakura, None; M
- Page 1581 and 1582:
dye “DiI” into the carotid body
- Page 1583 and 1584:
Authors: J.-H. ZHANG 1,2 , S. J. FU
- Page 1585 and 1586:
Support: NSERC Grant Department of
- Page 1587 and 1588:
Location: South Hall A Time: Tuesda
- Page 1589 and 1590:
(WT) obtained from the same colony,
- Page 1591 and 1592:
the activity of npEW-Ucn1 system du
- Page 1593 and 1594:
defeated and instead exposed to emp
- Page 1595 and 1596:
Title: Pre-locus coeruleus neurons
- Page 1597 and 1598:
573. Stress-Modulated Brain Pathway
- Page 1599 and 1600:
Poster 573. Stress-Modulated Brain
- Page 1601 and 1602:
estraint stress starting one week p
- Page 1603 and 1604:
increases VTA BDNF, which may influ
- Page 1605 and 1606:
t=3.177, df=12). Early and delayed
- Page 1607 and 1608:
CORT with the antagonist of GR or M
- Page 1609 and 1610:
paradigm designed to induce variabl
- Page 1611 and 1612:
Abstract: Neurogenesis in the hippo
- Page 1613 and 1614:
Title: Chronic corticosterone expos
- Page 1615 and 1616:
Program#/Poster#: 574.1/FF51 Topic:
- Page 1617 and 1618:
574. Entrainment and Phase Shifts:
- Page 1619 and 1620:
induced c-FOS cells was significant
- Page 1621 and 1622:
Poster 574. Entrainment and Phase S
- Page 1623 and 1624:
Ca2+i leak rate through RyR in vivo
- Page 1625 and 1626:
neuroprotection or neuronal death.
- Page 1627 and 1628:
phase to one that is consistent wit
- Page 1629 and 1630:
Disclosures: N. Atkins, None; S. Re
- Page 1631 and 1632:
Disclosures: L.S. Zhang , None; C.
- Page 1633 and 1634:
of withdrawal from morphine, the bl
- Page 1635 and 1636:
Title: Preliminary study of the exp
- Page 1637 and 1638:
Poster 574. Entrainment and Phase S
- Page 1639 and 1640:
Poster 574. Entrainment and Phase S
- Page 1641 and 1642:
Similar to the results with clock g
- Page 1643 and 1644:
investigation is necessary to ident
- Page 1645 and 1646:
Poster 575. Maintenance and Executi
- Page 1647 and 1648:
(color judgment) while at the same
- Page 1649 and 1650:
Intelligence and Processing Speed c
- Page 1651 and 1652:
Abstract: How the brain maintains s
- Page 1653 and 1654:
MA; 2 The Picower Inst. for Learnin
- Page 1655 and 1656:
Time: Tuesday, October 20, 2009, 8:
- Page 1657 and 1658:
Poster 575. Maintenance and Executi
- Page 1659 and 1660:
The study proceeded in two stages.
- Page 1661 and 1662:
NIH Grant AG0925 NSF Graduate Resea
- Page 1663 and 1664:
Poster 575. Maintenance and Executi
- Page 1665 and 1666:
eak, a surprising recognition task
- Page 1667 and 1668:
Title: Behavioral and neural eviden
- Page 1669 and 1670:
Topic: F.01.f. Working memory Suppo
- Page 1671 and 1672:
Location: South Hall A Time: Tuesda
- Page 1673 and 1674:
perceived each odor contributed to
- Page 1675 and 1676:
Program#/Poster#: 576.3/FF105 Topic
- Page 1677 and 1678:
in the subliminal condition. These
- Page 1679 and 1680:
with rPMC, and rPMC with rPC. There
- Page 1681 and 1682:
premotor regions, but modulated mor
- Page 1683 and 1684:
did not notice the delay. From this
- Page 1685 and 1686:
Location: South Hall A Time: Tuesda
- Page 1687 and 1688:
evidence by influencing the represe
- Page 1689 and 1690:
Authors: *R. M. KALWANI, J. I. GOLD
- Page 1691 and 1692:
Results: RT for correct responses w
- Page 1693 and 1694:
Title: Dissociable components of ob
- Page 1695 and 1696:
Authors: *G. C. DE GUZMAN 1 , J. LA
- Page 1697 and 1698:
Poster 577. Communication and Self:
- Page 1699 and 1700:
esponse creation compared to contro
- Page 1701 and 1702:
A Grant-in-Aid for Scientific Resea
- Page 1703 and 1704:
Location: South Hall A Time: Tuesda
- Page 1705 and 1706:
egions previously implicated as the
- Page 1707 and 1708:
NINDS grant NS048229-04 ONR Contrac
- Page 1709 and 1710:
577. Communication and Self: Other
- Page 1711 and 1712:
compared to that in the familiar fa
- Page 1713 and 1714:
to make it possible to scan the bra
- Page 1715 and 1716:
phylogenetically highly conserved n
- Page 1717 and 1718:
Topic: F.01.l. Social cognition Sup
- Page 1719 and 1720:
Support: CREST, 17022035 KAKENHI, 2
- Page 1721 and 1722:
Poster 578. Executive Function: Ani
- Page 1723 and 1724:
Disclosures: C.T. Miller, None; X.
- Page 1725 and 1726:
Poster 578. Executive Function: Ani
- Page 1727 and 1728:
trials were match trials and half w
- Page 1729 and 1730:
Authors: *M. ISODA 1,2 , K. YAKO 1,
- Page 1731 and 1732:
Time: Tuesday, October 20, 2009, 8:
- Page 1733 and 1734:
neural coding perspective the funct
- Page 1735 and 1736:
induced cognitive impairments. Alth
- Page 1737 and 1738:
Program#/Poster#: 579.6/GG21 Topic:
- Page 1739 and 1740:
Poster 579. Executive Function: Rod
- Page 1741 and 1742:
ehavioral and temporal information
- Page 1743 and 1744:
ecause this ability in nonhuman ani
- Page 1745 and 1746:
few information are available regar
- Page 1747 and 1748:
Authors: *S. GARCIA, F. PAPALEO, L.
- Page 1749 and 1750:
and cognitive flexibility occurs in
- Page 1751 and 1752:
Title: Prenatal protein malnutritio
- Page 1753 and 1754:
Employment (full or part-time); R.
- Page 1755 and 1756:
correlates of behavioral performanc
- Page 1757 and 1758:
Abstract: Like the proverbial moth
- Page 1759 and 1760:
Support: Roche-Palo Alto Department
- Page 1761 and 1762:
Poster 580. Executive Function: Rod
- Page 1763 and 1764:
Poster 580. Executive Function: Rod
- Page 1765 and 1766:
eward sensitivity. Results: BMI imp
- Page 1767 and 1768:
1999). Here, we examined the time c
- Page 1769 and 1770:
Support: NIH Grant MH48404 Pittsbur
- Page 1771 and 1772:
Poster 580. Executive Function: Rod
- Page 1773 and 1774:
Time: Tuesday, October 20, 2009, 8:
- Page 1775 and 1776:
581. Adult Neurogenesis and Cogniti
- Page 1777 and 1778:
During neurogenesis, immature denta
- Page 1779 and 1780:
training with the post-US cue was n
- Page 1781 and 1782:
gross structural neurological chang
- Page 1783 and 1784:
Authors: R. M. ALEKSEJEV 1 , *J. AM
- Page 1785 and 1786:
Authors: *C. L. PICKENS 1 , T. ADAM
- Page 1787 and 1788:
582. Stress and Behavior Location:
- Page 1789 and 1790:
582. Stress and Behavior Location:
- Page 1791 and 1792:
Support: HHMI (AMS) NIH Grant DA201
- Page 1793 and 1794:
Program#/Poster#: 582.11/GG73 Topic
- Page 1795 and 1796:
Poster 582. Stress and Behavior Loc
- Page 1797 and 1798:
Poster 583. Reward: Motivated Behav
- Page 1799 and 1800:
system. Ten healthy, normal-weight
- Page 1801 and 1802:
medial shell amplify ‘liking’ r
- Page 1803 and 1804:
Authors: *S. E. ROSS 1 , J. W. ALDR
- Page 1805 and 1806:
Topic: F.03.a. Reward Support: NIH
- Page 1807 and 1808:
Title: Activation of nucleus accumb
- Page 1809 and 1810:
Poster 583. Reward: Motivated Behav
- Page 1811 and 1812:
Disclosures: R. Sharf, None; M. Sar
- Page 1813 and 1814:
Disclosures: M. Baudonnat, None; J.
- Page 1815 and 1816:
RD for a block of trials. In the re
- Page 1817 and 1818:
Abstract: Operant tasks have been u
- Page 1819 and 1820:
Topic: F.03.a. Reward Title: The di
- Page 1821 and 1822:
Poster 583. Reward: Motivated Behav
- Page 1823 and 1824:
levels stabilized (13 cycles), both
- Page 1825 and 1826:
during development in the Bengalese
- Page 1827 and 1828:
Authors: P. V. LOVELL, *C. V. MELLO
- Page 1829 and 1830:
Time: Tuesday, October 20, 2009, 8:
- Page 1831 and 1832:
Disclosures: L. Remage-Healey, None
- Page 1833 and 1834:
examined behavioral and neural resp
- Page 1835 and 1836:
tegmental area (VTA) cell activatio
- Page 1837 and 1838:
millisecond before initiation of si
- Page 1839 and 1840:
lateral song transmission from tuto
- Page 1841 and 1842:
Authors: *B. A. PAWLISCH 1,2 , S. A
- Page 1843 and 1844:
Location: South Hall A Time: Tuesda
- Page 1845 and 1846:
number of round DCX-ir cells (diffe
- Page 1847 and 1848:
Title: LC/MS/MS analysis of in vivo
- Page 1849 and 1850:
previously exposed to novel objects
- Page 1851 and 1852:
controlling the adhesion, growth an
- Page 1853 and 1854:
MS). Previously this approach had b
- Page 1855 and 1856:
Topic: G.01. Molecular, Biochemical
- Page 1857 and 1858:
585. Molecular Methods to Monitor a
- Page 1859 and 1860:
586. Imaging Techniques VI Location
- Page 1861 and 1862:
post injury as compared to that of
- Page 1863 and 1864:
apoptosis (1). In the last decade m
- Page 1865 and 1866:
586. Imaging Techniques VI Location
- Page 1867 and 1868:
such as axons. EdU signal was prese
- Page 1869 and 1870:
586. Imaging Techniques VI Location
- Page 1871 and 1872:
Aβ. Tissue sections co-stained wit
- Page 1873 and 1874:
Support: AEG: Natl. Defense Science
- Page 1875 and 1876:
Poster 586. Imaging Techniques VI L
- Page 1877 and 1878:
Disclosures: Y. Ogawa, None; K. Osa
- Page 1879 and 1880:
Authors: *Z. ZENG 1 , S. O'MALLEY 2
- Page 1881 and 1882:
activation, along with the morpholo
- Page 1883 and 1884:
vivo. Because co-infectivity of AAV
- Page 1885 and 1886:
Authors: *L. C. FLORES, R. GALVEZ,
- Page 1887 and 1888:
Authors: J. A. CURRY, A. MOSS, S. T
- Page 1889 and 1890:
Authors: *A. E. KALYUZHNY 1 , J. P.
- Page 1891 and 1892:
Agence Nationale de Recherche grant
- Page 1893 and 1894:
587. Electrophysiological Recording
- Page 1895 and 1896:
587. Electrophysiological Recording
- Page 1897 and 1898:
procedures allowed the reliable ide
- Page 1899 and 1900:
completion IA HA injections. Method
- Page 1901 and 1902:
Poster 587. Electrophysiological Re
- Page 1903 and 1904:
Time: Tuesday, October 20, 2009, 8:
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