15.12.2012 Views

When citing an abstract from the 2009 Annual - Society for ...

When citing an abstract from the 2009 Annual - Society for ...

When citing an abstract from the 2009 Annual - Society for ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

trials were match trials <strong>an</strong>d half were nonmatch trials. The eight sound stimuli <strong>for</strong> each recording<br />

day were chosen <strong>from</strong> a larger sound set with each sound stimulus repeated 8-12 times on both<br />

match <strong>an</strong>d nonmatch trials within a recording session. Sound stimuli included pure tones,<br />

frequency sweeps, m<strong>an</strong>-made environmental sounds, monkey vocalizations, hum<strong>an</strong><br />

vocalizations, natural sounds, syn<strong>the</strong>sized sounds, <strong>an</strong>d o<strong>the</strong>r <strong>an</strong>imal sounds. Assessment of<br />

neuronal firing rates <strong>an</strong>d wave<strong>for</strong>ms were completed <strong>for</strong> task related activity, as well as <strong>for</strong> <strong>the</strong><br />

same sound stimuli during passive listening. Preliminary results <strong>from</strong> two monkeys indicate that<br />

neurons in this area are responsive to complex auditory stimuli in a selective m<strong>an</strong>ner during <strong>the</strong><br />

memory task. Single-units also signific<strong>an</strong>tly increase or decrease <strong>the</strong>ir firing rate compared to<br />

baseline <strong>for</strong> individual events during <strong>the</strong> behavioral per<strong>for</strong>m<strong>an</strong>ce, such as <strong>the</strong> delay period, <strong>the</strong><br />

waiting to behaviorally respond period, <strong>an</strong>d/or during <strong>the</strong> response period. Comparing single-unit<br />

activity <strong>for</strong> correct match trials versus incorrect nonmatch trials, wherein behavioral responses<br />

are made on both trial types, revealed specific increases in firing rate during trials with correct<br />

match per<strong>for</strong>m<strong>an</strong>ce. Neurons in this prefrontal region, area 46, encode complex auditory signals<br />

<strong>an</strong>d also have firing patterns correlated with specific portions of <strong>the</strong> task in addition to its<br />

auditory-related encoding.<br />

Disclosures: B. Plakke, None; C. Ng, None; R. Opheim, None; A. Poremba, None.<br />

Poster<br />

578. Executive Function: Animal Models of Audition, Vocalization, <strong>an</strong>d Social Interaction<br />

Location: South Hall A<br />

Time: Tuesday, October 20, <strong>2009</strong>, 8:00 am - 12:00 noon<br />

Program#/Poster#: 578.8/GG13<br />

Topic: F.02.b. Executive function<br />

Support: NIH DC007172<br />

NIH DC009224<br />

Title: Context-dependent neural representation of vocalizations in primate ventrolateral<br />

prefrontal cortex<br />

Authors: *A. E. BAKER 1 , J. TSUNADA 2 , S. J. DAVIS 2 , Y. E. COHEN 2 , A. A.<br />

GHAZANFAR 3 ;<br />

1 Psychological <strong>an</strong>d Brain Sci., Dartmouth Coll, H<strong>an</strong>over, NH; 2 Dept. of Otorhinolaryngology,<br />

Univ. of Pennsylv<strong>an</strong>ia Sch. of Med., Philadelphia, PA; 3 Neurosci. Institute, Dept. of Psychology,<br />

Princeton Univ., Princeton, NJ

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!