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BT August 2019

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<strong>BT</strong> Buzz<br />

Boy or girl? It’s in the father’s genes<br />

A Newcastle University study involving thousands of families<br />

is helping prospective parents work out whether they are<br />

likely to have sons or daughters. The work by Corry Gellatly, a<br />

research scientist at the university, has shown that men inherit<br />

a tendency to have more sons or more daughters from their<br />

parents. This means that a man with many brothers is more<br />

likely to have sons, while a man with many sisters is more<br />

likely to have daughters.<br />

The research involved a study of 927 family trees containing<br />

information on 556,387 people from North America and<br />

Europe going back to 1600. “The family tree study showed<br />

that whether you’re likely to have a boy or a girl is inherited.<br />

We now know that men are more likely to have sons if they<br />

have more brothers but are more likely to have daughters if<br />

they have more sisters. However, in women, you just can’t<br />

predict it,” Mr Gellatly explains.<br />

Low vitamin D at birth raises risk<br />

of higher blood pressure in kids<br />

Vitamin D deficiency from birth to early childhood was<br />

associated with an increased risk of elevated blood pressure in<br />

later childhood and adolescence, according to new research in<br />

the American Heart Association journal Hypertension.<br />

Researchers followed 775 children from birth to age<br />

18 at the Boston Medical Center. Most lived in a lowincome,<br />

urban area and 68% of the children were African<br />

American. Low vitamin D levels were defined as less<br />

than 11 ng/ml (nanograms per millimeter) in cord blood<br />

at birth and less than 25 ng/ml in a child’s blood during<br />

early childhood. Compared to children who were born<br />

with adequate vitamin D levels, those born with low levels<br />

of vitamin D had an approximately 60% higher risk of<br />

elevated systolic blood pressure between ages 6 and 18.<br />

Both mother and baby genes affect<br />

birth weight<br />

The largest study of its kind has led to new insights into the<br />

complex relationships surrounding how mothers’ and babies’<br />

genes influence birth weight. The research, published in<br />

Nature Genetics, identifies 190 links between our genetic<br />

code and birth weight, two-thirds of which are identified<br />

for the first time. It is the result of a large scale international<br />

collaboration, led by the universities of Exeter, Queensland,<br />

Oxford and Cambridge.<br />

Scientists have long known that babies who are particularly<br />

small at birth have a higher risk of birth complications, and also<br />

tend to be more prone than average weight babies to high<br />

blood pressure in adulthood. To understand the relationships<br />

between birth weight and such risks to health, it is necessary to understand the contributions of both genetics and the<br />

environment. But until now, these have been unclear. This study casts new light in this area by allowing scientists to clearly<br />

separate the effects of a mother’s genetics on birth weight from the baby’s own genetics for the first time.<br />

8 BabyTalk | <strong>August</strong> <strong>2019</strong>

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