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North Canterbury News: September 16, 2021

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ANIMAL HEALTH<br />

The <strong>North</strong> <strong>Canterbury</strong> <strong>News</strong>, <strong>September</strong> <strong>16</strong>, <strong>2021</strong><br />

21<br />

Local vet supports horse gel studies<br />

By SHELLEY TOPP<br />

A<strong>North</strong> <strong>Canterbury</strong>veterinarianis<br />

working withaUniversity of<br />

<strong>Canterbury</strong> academic to develop a<br />

wound­healinggel forhorses.<br />

Thegel,which is abreakthrough<br />

discovery in tissue regeneration, was<br />

developedfor humans by an<br />

internationalpartnershipled by<br />

ProfessorRudi Marquez,who is head<br />

of theuniversity’s School of Physical<br />

andChemical Sciences andadirector<br />

andco­founderofTissue Repair<br />

Technologies (TRT), acompany which<br />

originated from the University of<br />

DundeeinScotland.<br />

ProfessorMarquez worked with two<br />

otheracademics, Dr AnaSchor and Dr<br />

DavidNorman,todevelopthe gel,<br />

whichisasmall­molecule<br />

pharmaceuticalthatkick­starts<br />

healinginwoundsthatfail to heal<br />

quickly or properly.<br />

‘‘The TRT treatment, applied to a<br />

woundasagel, hasbeen shown to<br />

accelerate healing of aslow­healing<br />

leg woundand appears to regulate the<br />

overgrowth of tissue,’’ Professor<br />

Marquez says.<br />

‘‘The molecule in the gel could be<br />

particularlyusefulinthe treatment of<br />

diabetics withfoot ulcers.’’<br />

Non­healing(chronic) skinulcers<br />

arealso acommon occurrencein<br />

elderly patients.<br />

Althoughthe gel was initially<br />

formulatedfor human patients, TRT<br />

hasrecently extended its woundhealingstudies<br />

to include horses.<br />

Thecompany is workingwithLoburn<br />

veterinarian Becky Sutorius,of<br />

Rangiora Equine Services, to trial the<br />

effectiveness of the gel.<br />

Becky Sutorius<br />

‘‘Horsesare alot like diabetic<br />

human patientsinthat if theyget an<br />

injuryatthe bottom of theirleg,it<br />

doesn't heal verywell,’’ Professor<br />

Marquezsays.<br />

‘‘When they do heal, the process can<br />

lead to an overgrowth of tissue causing<br />

further problems.<br />

‘‘So extending ourstudy to horses<br />

offersusthe chance to make a<br />

significantcontributiontothe New<br />

Zealand horseindustry and at the<br />

sametimecontinue the development<br />

of human treatments.’’<br />

Becky saysthe overgrowth of tissue<br />

prevents wounds fromhealing, which<br />

increasesthe riskofbleedingand<br />

infectionand alsoincreases theriskof<br />

tumourformation.<br />

She began workingwithProfessor<br />

Marquez on theprojecttwo years ago<br />

and says theresults of her trial so far<br />

are ‘‘promising’’ in terms of reduced<br />

scartissue, faster healing, less<br />

downtime fromcompetition,improved<br />

welfare and lessstress on thehorses,<br />

Tissue repair ... Agel developed for humans could speed up the healing process for<br />

horse wounds.<br />

PHOTOS: FILE<br />

as well as reduced costs to the owners.<br />

Professor Marquez says theproduct<br />

is in theadvanceddevelopment stages,<br />

but still some wayfrom being approved<br />

for sale.<br />

‘‘Wewould like to carry out alarger<br />

trial, andthentoapplyfor<br />

registration,’’hesays.<br />

‘‘Weexpect this to take place in the<br />

next6­12 months.<br />

‘‘Atthe moment, we areexploring<br />

the possibility of using it in New<br />

Zealandinasimilarway as the<br />

cascade processinthe United<br />

Kingdom,whereby experimental<br />

drugs can be administered by a<br />

veterinarian on anon­commercial<br />

basis.’’<br />

Twosimilarproductswill be<br />

developed, onefor humansand one for<br />

horses.<br />

‘‘Thedosage will havetobe<br />

optimised, and will requirefurther<br />

regulatoryapproval,’’Professor<br />

Marquez says. ‘‘We want to make sure<br />

that we have aproduct that is effective<br />

andeasily affordable, althoughweare<br />

acompany, our main drive is to<br />

improvehumanand animal health.<br />

‘‘Ideally,wewould liketobeableto<br />

produceitand manufacture it locally<br />

in <strong>Canterbury</strong>’’’<br />

IT’S ABOUT TIME SOMEONE<br />

STARTED THINKING LIKE AFARMER.<br />

You have enough to do without worrying about the perfect drench programme. To help, we<br />

went back to basics to create the Turbo ® 3-stage parasite control programme for growing cattle.<br />

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innovative, reliable and available exclusively through leading veterinary practices nationwide.<br />

TURBO ® CATTLE DRENCH PROGRAMMEME<br />

STAGE1<br />

TURBO ® Initial<br />

Oral Drench<br />

First oral drenchtreatment for weaned calves.<br />

Protect against worm parasites and bridge<br />

the gap between removal of coccidiostat meal<br />

and natural coccidiosis immunity.<br />

STAGE2<br />

TURBO ® Advance<br />

Oral Drench<br />

Routinetreatment of growing<br />

cattle that canbedrenched orally.<br />

Can<br />

be used in cattle under 120kg.<br />

PROUDLY<br />

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OWNED<br />

Available exclusively through veterinary practices nationwide.<br />

Visit www.alleva.co.nz for more information.<br />

TURBO ® is aregistered trademark of Alleva Animal Health Ltd.TURBO Pour-on<br />

(A011722), TURBO Injection(A011742), TURBOInitial(A011703) and<br />

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See www.foodsafety.govt.nz for registration conditions.<br />

STAGE3<br />

TURBO ® Pour On<br />

or Injection<br />

Routine treatment for growing cattle that<br />

are too big to be drenched orally.Rain<br />

resistant pour-on and injectable options<br />

withthe added benefit of lice control.

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