North Canterbury News: September 16, 2021
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ANIMAL HEALTH<br />
The <strong>North</strong> <strong>Canterbury</strong> <strong>News</strong>, <strong>September</strong> <strong>16</strong>, <strong>2021</strong><br />
21<br />
Local vet supports horse gel studies<br />
By SHELLEY TOPP<br />
A<strong>North</strong> <strong>Canterbury</strong>veterinarianis<br />
working withaUniversity of<br />
<strong>Canterbury</strong> academic to develop a<br />
woundhealinggel forhorses.<br />
Thegel,which is abreakthrough<br />
discovery in tissue regeneration, was<br />
developedfor humans by an<br />
internationalpartnershipled by<br />
ProfessorRudi Marquez,who is head<br />
of theuniversity’s School of Physical<br />
andChemical Sciences andadirector<br />
andcofounderofTissue Repair<br />
Technologies (TRT), acompany which<br />
originated from the University of<br />
DundeeinScotland.<br />
ProfessorMarquez worked with two<br />
otheracademics, Dr AnaSchor and Dr<br />
DavidNorman,todevelopthe gel,<br />
whichisasmallmolecule<br />
pharmaceuticalthatkickstarts<br />
healinginwoundsthatfail to heal<br />
quickly or properly.<br />
‘‘The TRT treatment, applied to a<br />
woundasagel, hasbeen shown to<br />
accelerate healing of aslowhealing<br />
leg woundand appears to regulate the<br />
overgrowth of tissue,’’ Professor<br />
Marquez says.<br />
‘‘The molecule in the gel could be<br />
particularlyusefulinthe treatment of<br />
diabetics withfoot ulcers.’’<br />
Nonhealing(chronic) skinulcers<br />
arealso acommon occurrencein<br />
elderly patients.<br />
Althoughthe gel was initially<br />
formulatedfor human patients, TRT<br />
hasrecently extended its woundhealingstudies<br />
to include horses.<br />
Thecompany is workingwithLoburn<br />
veterinarian Becky Sutorius,of<br />
Rangiora Equine Services, to trial the<br />
effectiveness of the gel.<br />
Becky Sutorius<br />
‘‘Horsesare alot like diabetic<br />
human patientsinthat if theyget an<br />
injuryatthe bottom of theirleg,it<br />
doesn't heal verywell,’’ Professor<br />
Marquezsays.<br />
‘‘When they do heal, the process can<br />
lead to an overgrowth of tissue causing<br />
further problems.<br />
‘‘So extending ourstudy to horses<br />
offersusthe chance to make a<br />
significantcontributiontothe New<br />
Zealand horseindustry and at the<br />
sametimecontinue the development<br />
of human treatments.’’<br />
Becky saysthe overgrowth of tissue<br />
prevents wounds fromhealing, which<br />
increasesthe riskofbleedingand<br />
infectionand alsoincreases theriskof<br />
tumourformation.<br />
She began workingwithProfessor<br />
Marquez on theprojecttwo years ago<br />
and says theresults of her trial so far<br />
are ‘‘promising’’ in terms of reduced<br />
scartissue, faster healing, less<br />
downtime fromcompetition,improved<br />
welfare and lessstress on thehorses,<br />
Tissue repair ... Agel developed for humans could speed up the healing process for<br />
horse wounds.<br />
PHOTOS: FILE<br />
as well as reduced costs to the owners.<br />
Professor Marquez says theproduct<br />
is in theadvanceddevelopment stages,<br />
but still some wayfrom being approved<br />
for sale.<br />
‘‘Wewould like to carry out alarger<br />
trial, andthentoapplyfor<br />
registration,’’hesays.<br />
‘‘Weexpect this to take place in the<br />
next612 months.<br />
‘‘Atthe moment, we areexploring<br />
the possibility of using it in New<br />
Zealandinasimilarway as the<br />
cascade processinthe United<br />
Kingdom,whereby experimental<br />
drugs can be administered by a<br />
veterinarian on anoncommercial<br />
basis.’’<br />
Twosimilarproductswill be<br />
developed, onefor humansand one for<br />
horses.<br />
‘‘Thedosage will havetobe<br />
optimised, and will requirefurther<br />
regulatoryapproval,’’Professor<br />
Marquez says. ‘‘We want to make sure<br />
that we have aproduct that is effective<br />
andeasily affordable, althoughweare<br />
acompany, our main drive is to<br />
improvehumanand animal health.<br />
‘‘Ideally,wewould liketobeableto<br />
produceitand manufacture it locally<br />
in <strong>Canterbury</strong>’’’<br />
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