PELONEWS Spring/Summer 2023

PELONews Spring/Summer2023
Overview Organoids & Organ-on-a-chip
Organoids, and organ-on-a-chip, have
transformed the landscape of biomedical research
and clinical applications.
Organ-on-a-chip platforms replicate the complex
microenvironment of organs, integrating multiple
cell types and physiological functions onto a single
chip.
These systems enable researchers to study organlevel
responses, drug interactions, and disease
mechanisms with high precision.
The combination of organoids and organ-on-achip
technology offers a powerful approach to
simulate human organ systems and bridge the
gap between traditional in vitro models and
animal testing.
This advancement not only enhances our understanding of human biology and disease but also
contributes to the development of safer and more effective treatments, while reducing reliance on
animal models. The FDA's recognition of these technologies by no longer requiring animal testing
reinforces the importance of embracing human-relevant models and ethical alternatives
for advancing healthcare and scientific discoveries.
Read our article by scanning/clicking the QR code to find out more.
Intestine-on-a-Chip for Personalized Medicine
Intestine-on-a-chip models also
facilitate the study of gastrointestinal
diseases, e.g. inflammatory bowel
disease, by mimicking the
inflammatory responses and barrier
dysfunction observed in these
conditions.
Organoid products for R&D or GMP
• Organoid kits with cytokines, media and cells included for culture of organoids
• PhenoDrive
• ECM Mixtures
• Scilia ExtraGel ECM equivalent to the gold-standard in the industry.
• Apricell 3-in-1 plate for high throughput drug testing.
• Collagen (I, II, III, IV)
• Fibronectin
• Laminin
• Vitronectin
Scan/click the QR code to learn about out ECM for 2D & 3D cell culture.
6 I www.pelobiotech.com