Matrix metalloproteinases (MMPs): Chemical–biological functions ...
Matrix metalloproteinases (MMPs): Chemical–biological functions ...
Matrix metalloproteinases (MMPs): Chemical–biological functions ...
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Rajeshwar P. Verma was born in 1966 in Barh<br />
(India). He received his M.Sc. (1988) and<br />
Ph.D. (1992) degrees in chemistry from<br />
Magadh University, Bodh-Gaya. He spent a<br />
year at the same university as a postdoctoral<br />
fellow with Professor K. S. Sinha. He joined<br />
Roorkee University (now IIT Roorkee) as a<br />
research associate and worked with Professor<br />
S.M. Sondhi (1993–1997). He also worked as<br />
a Lecturer of Chemistry at Gurukula Kangri<br />
University, Hardwar (1994–1995). He won a<br />
Research Associateship Award in December<br />
1994 from the Council of Scientific and<br />
Industrial Research, New Delhi (India). In<br />
1997, he moved to Pomona College to join the renowned QSAR<br />
research group of Professor Corwin Hansch and Cynthia Selassie,<br />
working as a postdoctoral research associate. Dr. Verma’s research<br />
interests include the following: isolation, characterization, and synthesis<br />
of natural products derived from medicinal plants; chemistry of<br />
isothiocyanates; synthesis of biologically important heterocycles and<br />
phenolic compounds; quantitative structure–activity relationships<br />
(QSAR) and computer-assisted drug design.<br />
Corwin Hansch received his undergraduate<br />
education at the University of Illinois and his<br />
Ph.D. degree in organic chemistry from New<br />
York University in 1944. After working with<br />
the Du Pont Co., first on the Manhattan<br />
Project and then in Wilmington, DE, he<br />
joined the Pomona College faculty in 1946. He<br />
has remained at Pomona except for two sabbaticals:<br />
one at the Federal Institute of<br />
Technology in Zurich, Switzerland, with<br />
Professor Prelog and the other at the University<br />
of Munich with Professor Huisgen.<br />
The Pomona group published the first paper<br />
on the QSAR approach relating chemical<br />
structure with biological activity in 1962. Since then, QSAR has<br />
received widespread attention. He is an honorary fellow of the Royal<br />
Society of Chemistry and recently received the ACS Award for<br />
Computers in Chemical and Pharmaceutical Research for 1999.