Non-pharmacological interventions for caregivers ... - Update Software

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D A T A A N D A N A L Y S E S Comparison 1. Experimental versus control Outcome or subgroup title No. of studies No. of participants Statistical method Effect size 1 Informal caregiver stress and strain 5 Mean Difference (IV, Random, 95% CI) Subtotals only 1.1 Teaching procedural knowledge 1 255 Mean Difference (IV, Random, 95% CI) -8.67 [-11.30, -6.04] 1.2 Support and information 2 219 Mean Difference (IV, Random, 95% CI) -4.63 [-15.44, 6.18] 1.3 Psycho-educational 2 125 Mean Difference (IV, Random, 95% CI) -0.34 [-3.27, 2.59] 2 Global measures of stress or distress 2 Mean Difference (IV, Fixed, 95% CI) Subtotals only 2.1 Support and information 1 183 Mean Difference (IV, Fixed, 95% CI) -0.34 [-1.64, 0.96] 2.2 Psycho-educational 1 28 Mean Difference (IV, Fixed, 95% CI) -2.02 [-6.58, 2.54] 3 Anxiety (lying above the recommended clinical cut-point for symptoms and signs of anxiety) 1 Risk Ratio (M-H, Fixed, 95% CI) Subtotals only 3.1 Teaching procedural knowledge 1 271 Risk Ratio (M-H, Fixed, 95% CI) 0.42 [0.13, 1.29] 4 Depression (continuous outcome) 5 Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only 4.1 Teaching procedural knowledge 1 273 Std. Mean Difference (IV, Fixed, 95% CI) -0.61 [-0.85, -0.37] 4.2 Support and information 2 256 Std. Mean Difference (IV, Fixed, 95% CI) -0.06 [-0.31, 0.18] 4.3 Psycho-educational 2 116 Std. Mean Difference (IV, Fixed, 95% CI) 0.20 [-0.17, 0.57] 5 Health-related quality of life 2 Mean Difference (IV, Random, 95% CI) Subtotals only 5.1 Teaching procedural 1 250 Mean Difference (IV, Random, 95% CI) -11.97 [-15.59, - knowledge 8.35] 5.2 Support and information 1 91 Mean Difference (IV, Random, 95% CI) 3.64 [-3.51, 10.79] Non-pharmacological interventions for caregivers of stroke survivors (Review) Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. 48
Analysis 1.1. Comparison 1 Experimental versus control, Outcome 1 Informal caregiver stress and strain. Review: Non-pharmacological interventions for caregivers of stroke survivors Comparison: 1 Experimental versus control Outcome: 1 Informal caregiver stress and strain Study or subgroup Experimental Control Mean Difference Weight Mean Difference 1 Teaching procedural knowledge N Mean(SD) N Mean(SD) IV,Random,95% CI IV,Random,95% CI Kalra 2004 125 33.99 (9.52) 130 42.66 (11.79) 100.0 % -8.67 [ -11.30, -6.04 ] Subtotal (95% CI) 125 130 100.0 % -8.67 [ -11.30, -6.04 ] Heterogeneity: not applicable Test for overall effect: Z = 6.47 (P < 0.00001) 2 Support and information Mant 2000 93 3.66 (4.29) 90 4 (4.68) 62.3 % -0.34 [ -1.64, 0.96 ] Yoo 2007 18 82.44 (14.54) 18 94.16 (19.24) 37.7 % -11.72 [ -22.86, -0.58 ] Subtotal (95% CI) 111 108 100.0 % -4.63 [ -15.44, 6.18 ] Heterogeneity: Tau 2 = 48.38; Chi 2 = 3.95, df = 1 (P = 0.05); I 2 =75% Test for overall effect: Z = 0.84 (P = 0.40) 3 Psycho-educational Draper 2007 17 10.71 (6.47) 20 11.6 (3.28) 74.5 % -0.89 [ -4.28, 2.50 ] Hartke 2003 43 31.04 (15.39) 45 29.78 (12.09) 25.5 % 1.26 [ -4.54, 7.06 ] Subtotal (95% CI) 60 65 100.0 % -0.34 [ -3.27, 2.59 ] Heterogeneity: Tau 2 = 0.0; Chi 2 = 0.39, df = 1 (P = 0.53); I 2 =0.0% Test for overall effect: Z = 0.23 (P = 0.82) Non-pharmacological interventions for caregivers of stroke survivors (Review) Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. -20 -10 0 10 20 Favours experimental Favours control 49
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