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140 EvolDir December 1, 2012<br />

*Target Audience* Everybody using Bioinformatics<br />

methods is implicitly using statistical methods. Most<br />

people have had one or more semester courses in Statistics<br />

in their graduate education. For many, Statistics<br />

happened in their lives a long a time ago, and that<br />

makes it difficult to go back and manipulate the concepts<br />

with full confidence. Moreover, proper judgement<br />

of the results often calls for a deeper level of understanding<br />

than what is required to solve scholarly exercises.<br />

Attending this course is a chance of revisiting subjects<br />

like experimental design, hypothesis testing, inference<br />

and prediction in an intensive and systematic way. We<br />

will look into particular areas such as Bayesian Inference,<br />

Hidden Markov Chains and Multivariate methods<br />

with the attitude, eyes and brains of a statistician that<br />

/<br />

This message has been arbitrarily truncated at 5000 characters.<br />

To read the entire message look it up at http://life.biology.-<br />

mcmaster.ca/˜brian/evoldir.html<br />

Oeiras Portugal<br />

PopulationStructure Dec17-19<br />

IGC, Oeiras, Portugal<br />

Course Announcement<br />

IPSI12 Introduction to Population Structure Inference<br />

with Lounès Chikhi and Vitor Sousa<br />

IMPORTANT DATES for this Course Deadline for applications:<br />

November 30th 2012 Latest notification of<br />

acceptance: December 5th 2012 Course date: December<br />

17th - 19th 2012<br />

Candidates with adequate profile will be accepted in<br />

the next 72 hours after the application until we reach<br />

20 participants.<br />

http://gtpb.igc.gulbenkian.pt/bicourses/IPSI12/<br />

Overview<br />

Genetic data are increasingly used by ecologists and<br />

evolutionary biologists in general. It has thus become<br />

important for many biologists with different levels of experience<br />

to produce and analyse genetic data. In this<br />

short course we shall try to take a practical approach<br />

to the analysis of genetic data, but we will also provide<br />

some of the theoretical background required to under-<br />

stand the outputs of the software used. This course<br />

will be organised so as to mix sessions where important<br />

notions are introduced with practicals where freely<br />

available software will be used. While this will not be<br />

the focus of the course, we will also discuss genealogical<br />

(coalescent-based) simulation methods and those based<br />

on forward-in-time simulations. Altogether this will allow<br />

to discuss the potentialities and limitations of the<br />

tools available to the community.<br />

In this three-day course we will introduce the main concepts<br />

that underlie many of the population structured<br />

models that are frequently used in population genetics.<br />

We will focus on the importance of demographic history<br />

(e.g. effective sizes and migration patterns) in shaping<br />

genetic data. We will go through the basic notions that<br />

are central to population genetics, insisting particularly<br />

on the statistics used to measure genetic diversity and<br />

population differentiation. The course will also cover<br />

a short introduction to coalescent theory, Bayesian inference<br />

in population genetics and data simulation, as<br />

they are connected to what makes landscape genetics<br />

today on the basis of multilocus data.<br />

Most theory will be put into practice in practical sessions,<br />

analyzing real and/or simulated datasets. In<br />

these sessions, we will<br />

(i) look at measures of genetic diversity and differentiation<br />

using GENETIX; (ii) use methods to detect<br />

population structure as implemented in the programs<br />

GENECLASS2 and STRUCTURE; (iii) use geneland<br />

to detect genetic clusters using spatial information on<br />

the sampling locations of individuals, and (iv) learn<br />

how to perform coalescent simulations of genetic data<br />

(using SPAms and ms).<br />

Thank you for your interest! (deadline for applications<br />

Nov 30th)<br />

–<br />

Upcoming Training Courses in GTPB: http://gtpb.igc.gulbenkian.pt/bicourses/BFB12<br />

http:/-<br />

/gtpb.igc.gulbenkian.pt/bicourses/IB12A http:/-<br />

/gtpb.igc.gulbenkian.pt/bicourses/IPSI12 – Pedro<br />

Fernandes Instituto Gulbenkian de Ciência<br />

Apartado 14 2781-901 OEIRAS Tel +351 21 4407912<br />

http://gtpb.igc.gulbenkian.pt Pedro Fernandes<br />

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