E v o l D i r
E v o l D i r
E v o l D i r
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December 1, 2012 EvolDir 33<br />
Elizabeth Derryberry, Ph.D. Assistant Professor Department<br />
of Ecology & Evolutionary Biology Tulane<br />
University New Orleans, LA 70118 504-862-8285 (office)<br />
504-862-8706 (fax) elizabethderryberry.tulane.edu<br />
ederrybe@tulane.edu<br />
UBerne BacterialGenomeEvolution<br />
PhD position in bacterial genomic evolution<br />
A PhD position will be available for 3 years at the University<br />
of Berne to investigate the effect of range expansions<br />
on the genomic diversity of bacteria.<br />
Theoretical and simulation results suggest that spatially<br />
expanding populations should accumulate nonneutral<br />
mutations at a higher rate than stationary populations<br />
through the mechanism of gene surfing. The<br />
present research project aims at verifying these predictions<br />
in bacteria.<br />
We are looking for a very motivated PhD student to<br />
perform and analyse the output of a series of experiments<br />
with bacteria, measure their fitness at various<br />
stages of their expansions, analyse the evolution of their<br />
genome by Next Generation Sequencing, and study the<br />
effects of the accumulated mutations. These analyses<br />
will be done in close collaboration with Prof. Martin<br />
Ackermann in ETH Zurich. The candidate is expected<br />
to have a strong background in microbiology and a good<br />
exposure to evolutionary concepts. Additional knowledge<br />
in population genetics, bioinformatics and statistics<br />
will be a plus.<br />
The successful candidate will be able to further her/his<br />
education by following courses organized by Swiss inter-<br />
University doctoral programs in Population Genomics<br />
and Bioinformatics. The gross starting salary is about<br />
3,000 CHF per month (plus an additional 13th month)<br />
and will follow the Swiss NSF progression scale. The<br />
CMPG lab offers an international and very stimulating<br />
research environment and it is affiliated to the Swiss<br />
Institute of Bioinformatics. Berne is ideally located in<br />
the middle of Switzerland and Europe, and provides<br />
rich cultural and outdoor activities.<br />
Please send before December 1 2012, an application<br />
letter stating your motivation for the position, a CV,<br />
and contact information of two references to laurent.excoffier@iee.unibe.ch.<br />
Position start is expected<br />
to be February 2013. People who have already applied<br />
to a previous version of this announcement are discour-<br />
aged to re-apply<br />
Prof. Laurent Excoffier<br />
– Laurent Excoffier<br />
Computational and Molecular Population Genetics<br />
(CMPG) Institute of Ecology and Evolution, University<br />
of Bern 6, Baltzerstrasse, CH-3012 Bern,<br />
Switzerland Tel: +41 31 631 30 31 Fax: +41<br />
31 631 48 88 Email:laurent.excoffier@iee.unibe.ch<br />
http://cmpg.iee.unibe.ch Computational Population<br />
Genetics Swiss Institute of Bioinformatics<br />
(SIB) http://www.isb-sib.ch/groups/-<br />
Computational Population Genetics.htm Laurent<br />
Excoffier <br />
UBerne HumanGenomics<br />
PhD positions in human genomics<br />
A PhD positions will be available for 3 years at the<br />
University of Berne to investigate the effect of range<br />
expansions on human non-neutral genomic diversity.<br />
Theoretical and simulation results suggest that spatially<br />
expanding populations should accumulate nonneutral<br />
mutations at a higher rate than stationary populations<br />
through the mechanism of gene surfing. The<br />
present research project aims at verifying these predictions<br />
in humans.<br />
We are looking for a motivated PhD student to be involved<br />
in the analysis of full exomes of human individuals<br />
from a region of Québec known to have been<br />
recently colonized and where gene surfing has been evidenced<br />
(see http://www.sciencemag.org/content/334/-<br />
6059/1148.abstract). He/she should be also involved in<br />
the modeling and simulation of genomic regions under<br />
selection, and thus have a good background in population<br />
genomics or bioinformatics, and in statistics. Programming<br />
abilities (e.g. R, C++) will be a plus for this<br />
position.<br />
The successful candidate will be able to further her/his<br />
education by following courses organized by Swiss inter-<br />
University doctoral programs in Population Genomics<br />
and Bioinformatics. The gross starting salary is about<br />
3,000 CHF per month (plus an additional 13th month)<br />
and will follow the Swiss NSF progression scale. The<br />
CMPG lab offers an international and very stimulating<br />
research environment and it is affiliated to the Swiss<br />
Institute of Bioinformatics. Berne is ideally located in<br />
the middle of Switzerland and Europe, and provides