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Table 1: Review of training studies with a focus on tremor<br />
Study Design Sample Resistance based training group Result<br />
Bilodeau et al.<br />
(2000)<br />
Ranganathan et al.<br />
(2001)<br />
Kornatz et al.<br />
(2005)<br />
RCT<br />
RCT<br />
Keogh et al. (2007) RCT<br />
Keogh, et al (2010) RCT<br />
� 13 ET (6M |7F)<br />
� 8 training<br />
� 5 control<br />
� 28 OA<br />
� 14 training<br />
� 14 control<br />
Crossover � 10 OA (5M | 5F)<br />
� 11 OA (M)<br />
� 7 training<br />
� 4 control<br />
� 19 OA (M)<br />
� 7 Strength<br />
� 7 co-ordination<br />
� 5 control<br />
� Index finger abduction/adduction<br />
� 3 d/w x 4 wks<br />
� 6 sets x 10 reps<br />
� Load - 80% 1RM vs 20% 1RM (C)<br />
� ‘Weighted ball’ hand rolling task<br />
� 6 d/w x 8 wks<br />
� 2 x 10 min/d<br />
� Load – 150g<br />
� Index finger abduction<br />
� 3 d/w x 6 wks<br />
� 6 sets x 10 reps<br />
� Load – 10% 1RM (2 wks)<br />
� 70% 1RM (4 wks)<br />
� D/B Elbow flexion, wrist flexion & wrist<br />
extension<br />
� 2 d/w x 6wks<br />
� 3 sets x 8-10 reps<br />
� D/B Elbow flexion, wrist flexion & wrist<br />
extension<br />
� 2 d/w x 6 wks<br />
� 3 sets x 8-10 reps<br />
Chapter 2 – Literature Review<br />
� ↓ Force fluctuations<br />
� ↑ Strength<br />
� ↔ Peak tremor power/amplitude<br />
� ↔ Functional tasks<br />
� ↔ Control<br />
� ↑Finger pinch force<br />
� ↓Force fluctuations<br />
� ↑ Dexterity<br />
� ↔ Hand grip strength<br />
� ↔ Control<br />
� ↑ Strength<br />
� ↑ Dexterity<br />
� ↓Force fluctuations<br />
� ↓ Motor unit firing rate variability<br />
� ↑ Strength<br />
� ↓Finger pinch force variability<br />
� ↓Targeting error<br />
� ↑ Strength in untrained limb (crossover)<br />
� ↔ Control<br />
� ↓ Tremor amplitude<br />
� ↓ Tremor peak<br />
� ↓ Tremor power<br />
� ↑ Strength<br />
� ↓Muscle co-activation<br />
� Similar effects for co-ordination<br />
� ↔Control<br />
RCT = randomised controlled trial, ET = Essential tremor, OA = older adult, d/w = days per week, wks = weeks, reps = repetition, RM = repetition max, min/d = minutes per<br />
day, D/B = dumb bells, ↑ = increase, ↓ = decrease, ↔ = no change.<br />
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