NIH Research Festival 2012 Program - Research Festival - National ...

Concurrent Symposia Session I
Natcher Conference Center
Conference Room D
Quantitative biology at the single-cell level
Co-Chairs: Eric Batchelor, NCI; and Myong-Hee Sung, NCI
Advances in numerous areas of the biological and medical sciences will continue to
require a quantitative understanding of the complex network of biochemical interactions
underlying biological phenomena. Accurate analysis of such a network often requires
probing interactions at the level of individual cells. Emerging single-cell technologies and
methodologies are providing unprecedented opportunities to better understand a wide
variety of biological processes. Such insight is important not only for a basic understanding
of cell biology, but also for providing new therapeutic avenues for treating a wide range of
diseases, including cancer, immune disorders, and neurological diseases. This symposium
will highlight the research of experts from the intramural program who develop and use
various cutting-edge single-cell technologies including super-resolution microscopy,
high-content imaging, and dynamical network analysis. Their research illustrates how
these new quantitative approaches are being used to tackle a diverse range of
biomedical questions.
Iain Fraser, NIAID
High-content imaging analysis of pathogen-sensing systems
Hari Shroff, NIBIB
Sharper and faster: new imaging technologies for cells and embryos
Myong-Hee Sung, NCI
NF-kappaB dynamics on multiple timescales by live cell imaging
Sohyoung Kim, NCI
Testing in silico predictions of p53 dynamics by direct measurements of
transcription kinetics
Dylan Burnette, NIGMS
A role for actin arcs in the advance of migrating cells
Natalie Porat Shilom, NIDCR
Coordination of mitochondrial activity across the rat salivary glands epithelium imaged
by intravital two-photon microscopy
FARE Award Winner
22
Tuesday, October 9, 2012
3:00 p.m.–5:00 p.m.